Catalysis by phospholipase C δ1 requires that Ca2+ bind to the catalytic domain, but not the C2 domain

Biochemistry

Volumn 37, Issue 14, 1998, Pages 5020-5028

  Grobler, Jay A ^a,b   Hurley, James H ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C;

ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BINDING SITE; CALORIMETRY; CATALYSIS; ENZYME ACTIVITY; GEL FILTRATION; HYDROLYSIS; MICELLE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALORIMETRY; CATALYSIS; CHROMATOGRAPHY, GEL; HYDROLYSIS; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHOSPHOLIPASE C; PROTEIN BINDING; RATS; RECOMBINANT PROTEINS;

EID: 0032492721     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972952w     Document Type: Article

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