Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34

Biochemistry

Volumn 37, Issue 14, 1998, Pages 4722-4730

  Guan, Yue ^a   Hickey, Michael J ^a   Borgstahl, Gloria E O ^a   Hallewell, Robert A ^b   Lepock, James R ^c   O'Connor, Don ^d   Hsieh, Yunsheng ^e   Nick, Harry S ^e   Silverman, David N ^e   Tainer, John A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF WATERLOO   (Canada)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; TYROSINE;

ARTICLE; CELL SURVIVAL; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STABILITY; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTON TRANSPORT; STRUCTURE ACTIVITY RELATION; THERMOSTABILITY;

BINDING SITES; CALORIMETRY, DIFFERENTIAL SCANNING; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; SUPEROXIDE DISMUTASE; THERMODYNAMICS; TYROSINE;

EID: 0032492710     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972394l     Document Type: Article

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