Irreversible inhibition of zinc-containing protease by oxazolidinone derivatives. Novel inactivation chemistry

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 7, 1998, Pages 859-864

  Kim, Dong H ^a   Chung, Sang Jeon ^a   Kim, Eun Jung ^a   Tian, Guan Rong ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

OXAZOLIDINONE DERIVATIVE; PROTEINASE;

ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; REACTION ANALYSIS; STEREOISOMERISM;

CARBOXYPEPTIDASES; CARBOXYPEPTIDASES A; DRUG DESIGN; KINETICS; MOLECULAR STRUCTURE; OXAZOLES; PHENYLPROPIONATES; PROTEASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC;

EID: 0032492702     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00123-1     Document Type: Article

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