Effects of sodium restriction on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride: A meta-analysis

JAMA

Volumn 279, Issue 17, 1998, Pages 1383-1391

  Graudal, Niels A ^a,b   Galløe, Anders M ^a   Garred, Peter ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Department of Clinical Immunology   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ALDOSTERONE; CATECHOLAMINE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NORADRENALIN; RENIN; SODIUM; TRIACYLGLYCEROL;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; HUMAN; HYPERTENSION; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; SODIUM RESTRICTION; SODIUM URINE LEVEL; SYSTOLIC BLOOD PRESSURE;

EID: 0032490150     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.279.17.1383     Document Type: Review

References (107)

1. Intersalt Cooperative Research Group. Intersalt: an international study of electrolyte excretion and blood pressure: results for 24 hour urinary sodium and potassium excretion. BMJ. 1988;297:319-328.
2. Smith WCS, Crombie IK, Tavendale RT, Gulland SK, Tunstall-Pedoe HD. Urinary electrolyte excretion, alcohol consumption, and blood pressure in the Scottish Heart Health Study. BMJ. 1988;297:329-330.
3. Grobbee DE, Hofman A. Does sodium restriction lower blood pressure? BMJ. 1986;293:27-29.
4. Cutler JA, Follmann D, Elliot P, Suh I. An overview of randomised trials of sodium reduction and blood pressure. Hypertension. 1991;17(suppl 1):I27-I33.
5. Law MR, Frost CD, Wald NJ III. Analysis of data from trials of salt reduction. BMJ. 1991;302: 819-824.
6. Midgley JP, Matthew AG, Greenwood CMT, Logan AG. Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials. JAMA. 1996;275:1590-1597.
7. Parijs J, Joossens JV, Van der Linden L, Verstreken G, Amery AKPC. Moderate sodium restriction and diuretics in the treatment of hypertension. Am Heart J. 1973;85:22-34.
8. Mark AL, Lawton WJ, Abboud FM, Fitz AE, Connor WE, Heistad DD. Effects of high and low sodium intake on arterial pressure and forearm vascular resistance in borderline hypertension. Circ Res. 1975;36-37(suppl 1):I194-I198.
9. Morgan T, Gillies A, Morgan G, Adam W, Wilson M, Carney S. Hypertension treated by salt restriction. Lancet. 1978;1:227-230.
10. Sullivan JM, Ratts TE, Taylor JC, et al. Hemodynamic effects of dietary sodium in man. Hypertension. 1980;2:506-514.
11. Morgan TO, Myers JB. Hypertension treated by sodium restriction. Med J Aust. 1981;2:396-397.
12. Ambrosioni E, Costa FV, Borghi C, Montebugnoli L, Giordani MF, Magnani B. Effects of moderate salt restriction on intralymphocytic sodium and pressor response to stress in borderline hypertension. Hypertension. 1982;4:789-794.
13. MacGregor GA, Markandu ND, Best FE, et al. Double-blind randomised crossover trial of moderate sodium restriction in essential hypertension. Lancet. 1982;1:351-355.
14. Beard TC, Gray WR, Cooke HM, Barge R. Randomised controlled trial of a no-added-sodium diet for mild hypertension. Lancet. 1982;2:455-458.
15. Watt GCM, Edwards C, Hart JT, Hart M, Walton P, Foy CJW. Dietary sodium restriction for mild hypertension in general practice. BMJ. 1983;286: 432-436.
16. Silman AJ, Locke C, Mitchell P, Humpherson P. Evaluation of the effectiveness of a low sodium diet in the treatment of mild to moderate hypertension. Lancet. 1983;1:1179-1182.
17. Puska P, Nissinen A, Vartiainen E, et al. Controlled, randomised trial of the effect of dietary fat on blood pressure. Lancet 1983;1:1-5.
18. Koolen MI, Brummelen P. Sodium sensitivity in essential hypertension: role of the renin-angiotensin-aldosterone system and the predictive value of an intravenous frusemide test. J Hypertens. 1984; 2:55-59.
19. Richards AM, Espiner EA, Maslowski AH, et al. Blood pressure response to moderate sodium restriction and to potassium supplementation in mild essential hypertension. Lancet. 1984;1:757-761.
20. Erwteman TM, Nagelkerke N, Lubsen J, Koster M, Dunning AJ. β Blockade, diuretics and salt restriction for the management of mild hypertension: a randomised double blind trial. BMJ. 1984; 289:406-409.
21. Maxwell MH, Kushiro T, Dornfeld LP, Tuck ML, Waks AU. Blood pressure changes in obese hypertensive subjects during rapid weight loss: comparison of restricted vs unchanged salt intake. Arch Intern Med. 1984;144:1581-1584.
22. Fagerberg B, Anderson OK, Isakson B, Björntop P. Blood pressure control during weight reduction in obese hypertensive men: separate effects of sodium and energy restriction. BMJ. 1984;288: 11-14.
23. Resnick LM, Nicholson JP, Laragh JH. Alterations in calcium metabolism mediate dietary salt sensitivity in essential hypertension. Trans Assoc Am Physicians. 1985;98:313-321.
24. Logan AG. Sodium manipulation in the management of hypertension: the view against its general use. Can J Physiol Pharmacol. 1986;64:793-802.
25. Chalmers J, Morgan T, Doyle A, et al. Australian National Health and Medical Research Council dietary salt study in mild hypertension. J Hypertens. 1986;4(suppl 6):S629-S637.
26. Grobbee DE, Hofman A, Roelandt JT, Boomsma F, Schalekamp MA, Valkenburg HA. Sodium restriction and potassium supplementation in young people with mildly elevated blood pressure. J Hypertens. 1987;5:115-119.
27. MacGregor GA, Markandu ND, Singer DRJ, Cappucio FP, Shore AC, Sagnella GA. Moderate sodium restriction with angiotensin converting enzyme inhibitor in essential hypertension: a double blind study. BMJ. 1987;294:531-534.
28. Kurtz TW, Al-Bander H, Morris RC. "Salt sensitive" essential hypertension in men: is the sodium ion alone important ? N Engl J Med. 1987;317:1043-1048.
29. Morgan F, Anderson A. Sodium restriction can delay the return of hypertension in patients previously well-controlled on drug therapy. Can J Physiol Pharmacol. 1987;65:1752-1755.
30. Morgan T, Anderson A. Interaction in hypertensive men between sodium intake, converting enzyme inhibitor (enalapril), plasma renin and blood pressure control. J Hum Hypertens. 1988;1: 311-315.
31. Lawton WJ, Sinkey CA, Fitz AE, Mark AL. Dietary salt produces abnormal renal vasoconstrictor responses to upright posture in borderline hypertensive subjects. Hypertension. 1988;11:529-536.
32. Shore AC, Markandu ND, MacGregor GA. A randomised cross-over study to compare the blood pressure response to sodium loading with and without chloride in patients with essential hypertension. J Hypertens. 1988;6:613-617.
33. Australian National Health and Medical Research Council Dietary Salt Study Management Committee. Fall in blood pressure with modest reduction in dietary salt intake in mild hypertension. Lancet. 1989;1-399-402.
34. MacGregor GA, Markandu ND, Sagnella GA, Singer DRJ, Cappucio FP. Double-blind study of three sodium intakes and long-term effects of sodium restriction in essential hypertension. Lancet. 1989;2:1244-1247.
35. Dodson PM, Beevers M, Hallworth R, Webberly MJ, Fletscher RF, Taylor KG. Sodium restriction and blood pressure in hypertensive type II diabetics: randomised blind controlled and crossover studies of moderate sodium restriction and sodium supplementation. BMJ. 1989;298:227-230.
36. Dimsdale JE, Ziegler M, Mills P, Berry C. Prediction of salt sensitivity. Am J Hypertens. 1990;3: 429-435.
37. Parker M, Puddey IB, Beilin LJ, Vandongen R. Two-way factorial study of alcohol and salt restriction in treated hypertensive men. Hypertension. 1990;16:398-406.
38. Schmid M, Mann FE, Stein G, et al. Natriuresis-pressure relationship in polycystic kidney disease. J Hypertens. 1990;8:277-283.
39. Bruun NE, Skøtt P, Nielsen MD, et al. Normal renal tubular response to changes of sodium intake in hypertensive man. J Hypertens. 1990;8:219-227.
40. Egan BM, Weder AB, Petrin J, Hoffman RG. Neurohumoral and metabolic effects of short-term dietary NaCl restriction in men: relationship to salt-sensitivity status. Am J Hypertens. 1991;4:416-421.
41. Carney SL, Gillies AH, Smith AJ, Smitham S. Increased dietary sodium chloride in patients treated with antihypertensive drugs. Clin Exp Hypertens. 1991;A13:401-407.
42. Singer DR, Markandu ND, Sugden AL, Miller MA, MacGregor GA. Sodium restriction in hypertensive patients treated with a converting enzyme inhibitor and a thiazide. Hypertension. 1991;17:798-803.
43. Sciarrone SEG, Beilin LJ, Rouse IL, Rogers PB. A factorial study of salt restriction and a low-fat/ high-fibre diet in hypertensive subjects. J Hypertens. 1992;10:287-298.
44. Benetos A, Xiao YY, Cuche JL, Hannaert P, Safar M. Arterial effects of salt restriction in hypertensive patients: a 9-week, randomized, double-blind, crossover study. J Hypertens. 1992;10:355-360.
45. Del Rio A, Rodriguez Villamil JL. Metabolic effects of strict salt restriction in essential hypertensive patients. J Intern Med. 1993;233:409-414.
46. Ruilope LM, Lahera V. Influence of salt intake on the antihypertensive effect of carvedilol. J Hypertens. 1993;11(suppl 4):S17-S19.
47. Redon-Mas J, Abellan Aleman J, Aranda Lara P, et al. Antihypertensive activity of verapamil: impact of dietary sodium. J Hypertens. 1993;11:665-671.
48. Fotherby MD, Potter JF. Effects of moderate sodium restriction on clinic and twenty-four-hour ambulatory blood pressure in elderly hypertensive subjects. J Hypertens. 1993;11:657-663.
49. Buckley MG, Markandu ND, Sagnella GA, MacGregor GA. Brain and atrial natriuretic peptides: a dual peptide system of potential importance in sodium balance and blood pressure regulation in patients with essential hypertension. J Hypertens. 1994;12:809-813.
50. Jula AM, Karanko HM. Effects on left ventricular hypertrophy of long-term nonpharmacological treatment with sodium restriction in mild to moderate essential hypertension. Circulation. 1994;89: 1023-1031.
51. Zoccali C, Mallamaci F, Parlongo S. The influence of salt intake on plasma calcitonin gene-related peptide in subjects with mild essential hypertension. J Hypertens. 1994;12:1249-1253.
52. Weir MR, Dengel DR, Behrens MT, Goldberg AP. Salt-induced increases in systolic blood pressure affect renal hemodynamics and proteinuria. Hypertension. 1995;25:1339-1344.
53. Overlack A, Ruppert M, Kolloch R, Kraft K, Stumpe KO. Age is a major determinant of the divergent blood pressure responses to varying salt intake in essential hypertension. Am J Hypertens. 1995;8:829-836.
54. Ferri C, Bellini C, Carlomagno A, Desideri G, Santucci A. Active kallikrein response to changes in sodium-chloride intake in essential hypertensive patients. Am Soc Nephrol 1996;7:443-453.
55. Feldmann RD, Logan AG, Schmidt ND. Dietary salt restriction increases vascular insulin resistance. Clin Pharmacol Ther. 1996;60:444-451.
56. Mühlhauser I, Prange K, Sawicki PT, et al. Effects of dietary sodium on blood pressure in IDDM patients with nephropathy. Diabetologia. 1996;39: 212-219.
57. McCarron DA, Weder AB, Egan BE, et al. Blood pressure and metabolic responses to moderate sodium restriction in isradipine treated hypertensive patients. Am J Hypertens. 1997;10:68-76.
58. Cappuccio FP, Markandu ND, Carney C, Sagnella CA, MacGregor GA. Double-blind randomised trial of modest salt restriction in older people. Lancet. 1997;350:850-854.
59. Skrabal F, Auböck J, Hörtnagel H. Low sodium/ high potassium diet for prevention of hypertension: probable mechanisms of action. Lancet. 1981;2:895-900.
60. Myers J, Morgan T, Waga S, Manley K. The effect of sodium intake on blood pressure related to the age of the patients. Clin Exp Pharmacol Physiol. 1982;9:287-289.
61. Cooper R, Van Horn L, Liu K, et al. A randomised trial of the effect of decreased dietary sodium intake on blood pressure in adolescents. J Hypertens. 1984;2:361-366.
62. Skrabal F, Herholz H, Neumayr M, et al. Salt sensitivity in humans is linked to enhanced sympathetic responsiveness and to enhanced proximal tubular reabsorption. Hypertension. 1984;6:152-158.
63. Skrabal F, Hamberger L, Cerny E. Salt sensitivity in normotensives with and salt resistance in normotensives without heredity of hypertension. Scand J Clin Lab Invest. 1985;176(suppl):47-57.
64. Watt GCM, Foy CJW, Hart JT, et al. Dietary sodium and arterial blood pressure: evidence against genetic susceptibility. BMJ. 1985;291:1525-1528.
65. Teow BH, Nicolantonio RD, Morgan TO. Sodium chloride preference and recognition threshold in normotensive subjects on high and low salt diet. Clin Exp Hypertens. 1986;A7:1681-1695.
66. Richards AM, Tonolo G, Cleland JG, et al. Plasma atrial natriuretic peptide: responses to modest and severe sodium restriction. J Hypertens. 1986;4(suppl):S559-S563.
67. Fuchs FD, Wannmacher CMD, Wannmacher L, et al. Effect of sodium intake on blood pressure, serum levels and renal excretion of sodium and potassium in normotensives with and without familial predisposition to hypertension. Braz J Med Biol Res. 1987;20:25-34.
68. El Ashry A, Heagerty AM, Alton SM, Bing RF, Swales JD, Thurston H. Effects of manipulation of sodium balance on erythrocyte sodium transport. J Hum Hypertens. 1987;1:105-111.
69. Hargreaves M, Morgan TO, Snow R, Guerin M. Exercise tolerance in the heat on low and normal salt intake. Clin Sci. 1989;76:553-557.
70. Mtabaji JP, Nara Y, Yamori Y. The cardiac study in Tanzania: salt intake in the causation and treatment of hypertension. J Hum Hypertens. 1990; 4:80-81.
71. Friberg P, Meredith I, Jennings G, Lambert G, Fazio V, Esler M. Evidence for increased renal norepinephrine overflow during sodium restriction in humans. Hypertension. 1990;16:121-130.
72. Hypertension Prevention Trial Research Group. The Hypertension Prevention Trial: three-year effects of dietary changes on blood pressure. Arch Intern Med. 1990;150:153-162.
73. Sharma AM, Arntz HR, Kribben A, Schattenfroh S, Distler A. Dietary sodium restriction: adverse effects on plasma lipids. Klin Wochenschr. 1990;68:664-668.
74. Ruppert M, Diehl J, Kolloch R, et al. Short term dietary sodium restriction increases serum lipids and insulin in salt-sensitive and salt-resistant normotensive adults. Klin Wochenschr. 1991;69(suppl 25):51-57.
75. Sharma AM, Ruland K, Spies KP, Distler A. Salt sensitivity in young normotensive subjects is associated with a hyperinsulinemic response to oral glucose. J Hypertens. 1991;9:329-335.
76. Mascioli S, Grimm R Jr, Launer C, et al. Sodium chloride raises blood pressure in normotensive subjects: the study of sodium and blood pressure. Hypertension. 1991;17(suppl 1):I21-I26.
77. Steegers EAP, Van Lakwijk HP, Jongsma HW, et al. (Patho)physiological implications of chronic dietary sodium restriction during pregnancy: a longitudinal prospective randomised study. Br J Obstet Gynaecol. 1991;98:980-987.
78. Cobiac L, Nestel PJ, Wing LMH, Howe PRC. A low sodium diet supplemented with fish oil lowers blood pressure in the elderly. J Hypertens. 1992;10: 87-92.
79. The Trials of Hypertension Prevention Collaborative Group. The effects of nonpharmacologic interventions on blood pressure of persons with high normal levels: results of the Trials of Hypertension Prevention, phase I. JAMA. 1992;267:1213-1220.
80. Burnier M, Rutschmann B, Nussberger J, et al. Salt dependent renal effects of an angiotensin II antagonist in healthy subjects. Hypertension. 1993; 22:339-347.
81. Ruppert M, Overlack A, Kolloch R, Kraft K, Göbel B, Stumpe KO. Neurohormonal and metabolic effects of severe and moderate salt restriction in non-obese normotensive adults. J Hypertens. 1993;11:743-749.
82. Sharma AM, Schorr U, Thiede HM, Distler A. Effect of dietary salt restriction on urinary serotonin and 5-hydroxyindolacetic acid excretion in man. J Hypertens. 1993;11:1381-1386.
83. Fliser D, Nowack R, Allendorf-Ostwald N, Kohl B, Hubinger A, Ritz E. Serum lipid changes on low salt diet: effects of alpha 1-adrenergic blockade. Am J Hypertens. 1993;6:320-324.
84. Nestel PJ, Clifton PM, Noakes M, McArthur R, Howe PR. Enhanced blood pressure response to dietary salt in elderly women, especially those with small waist:hip ratio. J Hypertens. 1993;11:1387-1394.
85. Donovan DS, Solomon CG, Seely EW, Williams GH, Simonson DC. Effect of sodium intake on insulin sensitivity. Am J Physiol. 1993;264:E730-E734.
86. Grey A, Braatvedt G, Holdaway I. Moderate dietary salt restriction does not alter insulin resistance or serum lipids in normal men. Am J Hypertens. 1996;9:317-322.
87. Schorr U, Distler A, Sharma AM. Effect of sodium chloride-and sodium bicarbonate-rich mineral water on blood pressure and metabolic parameters in elderly normotensive individuals: a randomized double-blind crossover trial. J Hypertens. 1996;14: 131-135.
88. Miller JA. Renal responses to sodium restriction in patients with early diabetes mellitus. J Am Soc Nephrol. 1997;8:749-755.
89. Schorr U, Beige J, Ringel J, et al. Hpa II polymorphism of the atrial natriuretic peptide gene and the blood pressure response to salt intake in normotensive men. J Hypertens. 1997;15:715-718.
90. Rosenthal R. Meta-analytic Procedures for Social Research. Beverly Hills, Calif: Sage; 1984.
91. National Bureau of Standards. Tables of normal probability functions. In: Applied Mathematics Series 23. Washington, DC: National Bureau of Standards; 1953.
92. Koolen MI, Brummelen P. Adrenergic activity and peripheral hemodynamics in relation to sodium sensitivity in patients with essential hypertension. Hypertension. 1984;6:820-825.
93. Overlack A, Ruppert M, Kolloch R, et al. Divergent hemodynamic and hormonal responses to varying salt intake in normotensive subjects. Hypertension. 1993;22:331-338.
94. Jula AM, Rönnemaa T, Tikkanen I, Karanko HM. Responses of atrial natriuretic factor to long-term sodium restriction in mild to moderate hypertension. J Intern Med. 1992;231:521-529.
95. Jula AM, Rönnemaa T, Piha SJ, Måki JP. Response of diastolic blood pressure to long-term sodium restriction is posture related. Scand J Clin Lab Invest. 1992;52:159-167.
96. Ruppert M, Overlack A, Kolloch R, Kraft K, Lennarz M, Stumpe KO. Effects of severe and moderate salt restriction on serum lipids in nonobese normotensive adults. Am J Med Sci. 1994;307(suppl 1):S87-S90.
97. Cutler JA, Follmann D, Allender PS. Randomized trials of sodium reduction: an overview. Am J Clin Nutr. 1997:65(suppl):643S-651S.
98. Oliver JW, Cohen EL, Neel JV. Blood pressure, sodium intake, and sodium related hormones in the Yanomamo Indians, a "no-salt" culture. Circulation. 1975;52:146-151.
99. Warren SE, Vieweg WVR, O'Connor DT. Sympathetic nervous system activity during sodium restriction in essential hypertension. Clin Cardiol. 1980;3:348-351.
100. Elliot P, Stamler J, Nichols R, et al. Intersalt revisited: further analyses of 24 hour sodium excretion and blood pressure within and across populations. BMJ. 1996;312:1249-1253.
101. Stamler R. Implications of the Intersalt study. Hypertension. 1991;17(suppl 1):I16-I20.
102. Counsell CE, Clarke MJ, Slattery J, Sandercock PAG. The miracle of DICE therapy for acute stroke: fact or fictional product of subgroup analysis. BMJ. 1994;309:1677-1681.
103. Alderman MH, Madhavan S, Ooi WL, Cohen H, Sealey JE, Laragh JH. Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension. N Engl J Med. 1991; 324:1098-1104.
104. Alderman MH, Madhavan S, Cohen H, Sealey JE, Laragh JH. Low urinary sodium is associated with greater risk of myocardial infarction among treated hypertensive men. Hypertension. 1995;25: 1144-1152.
105. Meade TW, Cooper JA, Peart WS. Plasma renin activity and ischemic heart disease. N Engl J Med. 1993;332:616-619.
106. Meltzer JI. Low urinary sodium and myocardial infarction. Hypertension. 1996;27:156.
107. MacGregor G. Low urinary sodium and myocardial infarction. Hypertension. 1996;27:156.