Cytotoxicity of a series of mono- and di-substituted thiourea in freshly isolated rat hepatocytes: A preliminary structure-toxicity relationship study

Toxicology

Volumn 125, Issue 2-3, 1998, Pages 117-129

  Onderwater, Rob C A ^a   Commandeur, Jan N M ^a   Groot, Ed J ^a   Sitters, Astrid ^a   Menge, Wiro M P B ^a   Vermeulen, Nico P E ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Hepatocytes; Structure toxicity relationships; Thiourea

Indexed keywords

BENZYLTHIOURACIL; PHENYLTHIOUREA;

ANIMAL EXPERIMENT; ARTICLE; CYTOPATHOGENIC EFFECT; ENZYME ACTIVITY; LIVER MICROSOME METABOLISM; LIVER TOXICITY; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ANIMALS; CELL SEPARATION; CELL SURVIVAL; DRUG EVALUATION, PRECLINICAL; GLUTATHIONE; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; LIVER; MALE; OXIDATION-REDUCTION; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP; THIOCHOLINE; THIOUREA;

EID: 0032489059     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(97)00169-8     Document Type: Article

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