Non-linear elution effects in split-peak chromatography II. Role of ligand heterogeneity in solute binding to columns with adsorption-limited kinetics

Journal of Chromatography A

Volumn 795, Issue 2, 1998, Pages 185-198

  Rollag, John G ^a   Hage, David S ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

Adsorption; Kinetics; Ligand heterogeneity; Proteins; Split peak effect; Stationary phases, LC

Indexed keywords

PROTEIN A; PROTEIN G;

ADSORPTION CHROMATOGRAPHY; AFFINITY CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL MODEL; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION;

ADSORPTION; CHROMATOGRAPHY, AFFINITY; COMPUTER SIMULATION; INDICATORS AND REAGENTS; KINETICS; LIGANDS; NONLINEAR DYNAMICS; PROTEINS; SOLUTIONS;

EID: 0032488944     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(97)00975-8     Document Type: Article

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