1. Endothelin antagonists: Search for surrogates of methylendioxyphenyl by means of a kohonen neural network

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 1, 1998, Pages 11-16

  Anzali, Soheila ^a   Mederski, Werner W K R ^a   Osswald, Mathias ^a   Dorsch, Dieter ^a  

^a MERCK KGAA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BENZODIOXOLE DERIVATIVE; BENZOTHIADIAZINE DERIVATIVE; BENZOTHIAPYRAZOLE; CYTOCHROME P450; ENDOTHELIN; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; METHYLENDIOXYPHENYL;

ARTICLE; ARTIFICIAL NEURAL NETWORK; CHEMICAL STRUCTURE; DRUG DESIGN; NONHUMAN; SURFACE PROPERTY; VASOCONSTRICTION; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; METABOLISM; STRUCTURE ACTIVITY RELATION;

CYTOCHROME P-450 ENZYME SYSTEM; DIOXOLES; ENDOTHELINS; NEURAL NETWORKS (COMPUTER); STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0032488450     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10150-0     Document Type: Article

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