Benzylic C-glycosides via the Ramberg-Backlund reaction

Tetrahedron Letters

Volumn 39, Issue 45, 1998, Pages 8225-8228

  Belica, Peter S ^a   Franck, Richard W ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSIDE;

ARTICLE; DRUG SYNTHESIS; HYDROGENATION; OXIDATION; REACTION ANALYSIS;

EID: 0032487986     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01881-4     Document Type: Article

References (24)

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19. 2), 3.74-3.62 (4H,m, H-3,H-2,H-1,H-1′),3.49 (1H,dt, J=2,9 Hz, H-6), 3.36-3.33 (2H,m,H-4,H-5), 3.15(1H,dd, J=1.8,14.2 Hz, H7, 2.73(1H,dd,J=8.8,14.2 Hz, H-7′). These conditions afford low yields of Ramberg-Backlund products in non-benzylic sulfones. Our modified method for achieving good yields in non-benzylic carbohydrate sulfones will be described in a future publication.
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24. 14 These results are taken from the Ph.D. thesis of PSB to be submitted to CUNY Graduate School in 1998. The authors thank HLR for support of this project; and thank Drs. Coffen, Manchand, and Wolff for their advice and encouragement.