Hippocampal lesions disrupt navigation based on cognitive maps but not heading vectors

Nature

Volumn 396, Issue 6706, 1998, Pages 75-77

  Pearce, John M ^a   Roberts, Amanda D L ^a   Good, Mark ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; COGNITION; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; COGNITION; HIPPOCAMPUS; MALE; MAZE LEARNING; ORIENTATION; RATS; SWIMMING;

EID: 0032487871     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/23941     Document Type: Article

References (8)

1. O'Keefe, J. & Nadel, L. The Hippocampus as a Cognitive Map (Clarendon, Oxford, 1978).
2. Collett, T. S., Cartwright, B. A. & Smith, B. A. Landmark learning and visuo-spatial memories in gerbils. J. Comp. Physiol. A 158, 835-851 (1986).
3. Morris, R. G. M., Garrud, P., Rawlins, J. N. P. & O'Keefe, J. Place navigation impaired in rats with hippocampal lesions. Nature 297, 681-683 (1982).
4. Roberts, A. D. L. & Pearce, J. M. Control of spatial behavior by an unstable landmark. J. Exp. Psychol. Anim. Behav. Proc. 24, 172-184 (1998).
5. Jarrard, L. E. On the use of ibotenic acid to lesion selectively different components of the hippocampal formation. J. Neurosci. Methods 29, 251-259 (1989).
6. Morris, R. G. M. Spatial localization does not require the presence of local cue. Learning Motiv. 12, 239-260 (1981).
7. Galistel, C. R. The Organization of Learning (MIT Press, Cambridge, MA, 1990).
8. Rescorla, R. A. & Wagner, A. R. in Classical Conditioning II: Current Research and Theory (eds Black, A. H. & Prokasy, W. F.) 64-99 (Appleton-Century-Crofts, New York, 1972).