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1
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0010349622
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Formerly Arris Pharmaceuticals
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1. Formerly Arris Pharmaceuticals
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2
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0000074870
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2. For reviews see: Gordon, E.M.; Gallop, MA.; Patel, D.V. Acc. Chem. Res. 1996, 29, 144. Thompson, L.A.; Ellman, J.A. Chem. Rev. 1996, 95, 555. Fruchtel, J.S.; Jung, G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Terrett, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron, 1995, 51, 8135.
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Gordon, E.M.1
Gallop, M.A.2
Patel, D.V.3
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3
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7044263277
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2. For reviews see: Gordon, E.M.; Gallop, MA.; Patel, D.V. Acc. Chem. Res. 1996, 29, 144. Thompson, L.A.; Ellman, J.A. Chem. Rev. 1996, 95, 555. Fruchtel, J.S.; Jung, G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Terrett, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron, 1995, 51, 8135.
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Chem. Rev.
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Thompson, L.A.1
Ellman, J.A.2
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4
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33748237769
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2. For reviews see: Gordon, E.M.; Gallop, MA.; Patel, D.V. Acc. Chem. Res. 1996, 29, 144. Thompson, L.A.; Ellman, J.A. Chem. Rev. 1996, 95, 555. Fruchtel, J.S.; Jung, G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Terrett, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron, 1995, 51, 8135.
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(1996)
Angew. Chem. Int. Ed. Engl.
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Fruchtel, J.S.1
Jung, G.2
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5
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0029065615
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2. For reviews see: Gordon, E.M.; Gallop, MA.; Patel, D.V. Acc. Chem. Res. 1996, 29, 144. Thompson, L.A.; Ellman, J.A. Chem. Rev. 1996, 95, 555. Fruchtel, J.S.; Jung, G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Terrett, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron, 1995, 51, 8135.
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(1995)
Tetrahedron
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Terrett, N.K.1
Gardner, M.2
Gordon, D.W.3
Kobylecki, R.J.4
Steele, J.5
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6
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0001176887
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3. a) Backes, B.J.; Virgilio, A.A.; Ellman, J.A. J. Am. Chem. Soc. 1996, 118, 3055.
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Backes, B.J.1
Virgilio, A.A.2
Ellman, J.A.3
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f) Voyer, N.; Lavoie, A; Pinette, M.; Bernier, J. Tetrahedron Lett. 1994, 35, 355.
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Voyer, N.1
Lavoie, A.2
Pinette, M.3
Bernier4
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12
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0032510277
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4. a) Breitenbucher, J.G.; Johnson, C.R.; Haight, M.; Phelan, J.C. Tetrahedron Lett. 1998, 39, 1295.
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Breitenbucher, J.G.1
Johnson, C.R.2
Haight, M.3
Phelan, J.C.4
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15
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0010351619
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5. Mattson, R.J.; Pham, K.M.; Leuck, D.J.; Cowen, K.A. J. Org. Chem. 1990, 55, 2553.
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Mattson, R.J.1
Pham, K.M.2
Leuck, D.J.3
Cowen, K.A.4
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16
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0010305393
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3 reductive amination on solid support was reported in a poster presentation Org. Div. Poster #91
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3 reductive amination on solid support was reported in a poster presentation by: DiCesare, J.C.; McComas, C.B.; Thomas, J.; Carrol, F.I. 211th National ACS Meeting, 1996, Org. Div. Poster #91.
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(1996)
211th National Acs Meeting
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DiCesare, J.C.1
McComas, C.B.2
Thomas, J.3
Carrol, F.I.4
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17
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0023030013
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7. Ashwood, V.A.; Buckingham, R.E.; Cassidy, F.; Evans, J.M.; Faruk, E.A.; Hamilton, T.C.; Nash, D.J.; Stemp, G.; Willcocks, K. J. Med. Chem. 1986, 29, 2194. Lipinski, C.A.; Aldinger, C.E.; Beyer, T.A.; Bordner, J.; Burdi, D.F.; Bussolotti, D.L.; Inskeep, P.B. J. Med. Chem. 1992, 35, 2169. Gadwood, R.C.; Kamdar, B.V.; Dubray, L.A.C.; Wolfe, M.L.; Smith, M.P.; Watt, W.; Mizsak, S.A.; Groppi, V.E. J. Med. Chem. 1993, 36, 1480. Atwal, K.S.; Grover, G.J.; Ahmed, S.Z.; Sleph, P.G.; Dzwonczyk, S.; Baird, A.J.; Normandin, D.E. J. Med. Chem. 1995, 38, 3236.
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Ashwood, V.A.1
Buckingham, R.E.2
Cassidy, F.3
Evans, J.M.4
Faruk, E.A.5
Hamilton, T.C.6
Nash, D.J.7
Stemp, G.8
Willcocks, K.9
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0026652442
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7. Ashwood, V.A.; Buckingham, R.E.; Cassidy, F.; Evans, J.M.; Faruk, E.A.; Hamilton, T.C.; Nash, D.J.; Stemp, G.; Willcocks, K. J. Med. Chem. 1986, 29, 2194. Lipinski, C.A.; Aldinger, C.E.; Beyer, T.A.; Bordner, J.; Burdi, D.F.; Bussolotti, D.L.; Inskeep, P.B. J. Med. Chem. 1992, 35, 2169. Gadwood, R.C.; Kamdar, B.V.; Dubray, L.A.C.; Wolfe, M.L.; Smith, M.P.; Watt, W.; Mizsak, S.A.; Groppi, V.E. J. Med. Chem. 1993, 36, 1480. Atwal, K.S.; Grover, G.J.; Ahmed, S.Z.; Sleph, P.G.; Dzwonczyk, S.; Baird, A.J.; Normandin, D.E. J. Med. Chem. 1995, 38, 3236.
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Lipinski, C.A.1
Aldinger, C.E.2
Beyer, T.A.3
Bordner, J.4
Burdi, D.F.5
Bussolotti, D.L.6
Inskeep, P.B.7
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19
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0027230173
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7. Ashwood, V.A.; Buckingham, R.E.; Cassidy, F.; Evans, J.M.; Faruk, E.A.; Hamilton, T.C.; Nash, D.J.; Stemp, G.; Willcocks, K. J. Med. Chem. 1986, 29, 2194. Lipinski, C.A.; Aldinger, C.E.; Beyer, T.A.; Bordner, J.; Burdi, D.F.; Bussolotti, D.L.; Inskeep, P.B. J. Med. Chem. 1992, 35, 2169. Gadwood, R.C.; Kamdar, B.V.; Dubray, L.A.C.; Wolfe, M.L.; Smith, M.P.; Watt, W.; Mizsak, S.A.; Groppi, V.E. J. Med. Chem. 1993, 36, 1480. Atwal, K.S.; Grover, G.J.; Ahmed, S.Z.; Sleph, P.G.; Dzwonczyk, S.; Baird, A.J.; Normandin, D.E. J. Med. Chem. 1995, 38, 3236.
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(1993)
J. Med. Chem.
, vol.36
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Gadwood, R.C.1
Kamdar, B.V.2
Dubray, L.A.C.3
Wolfe, M.L.4
Smith, M.P.5
Watt, W.6
Mizsak, S.A.7
Groppi, V.E.8
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0029166716
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7. Ashwood, V.A.; Buckingham, R.E.; Cassidy, F.; Evans, J.M.; Faruk, E.A.; Hamilton, T.C.; Nash, D.J.; Stemp, G.; Willcocks, K. J. Med. Chem. 1986, 29, 2194. Lipinski, C.A.; Aldinger, C.E.; Beyer, T.A.; Bordner, J.; Burdi, D.F.; Bussolotti, D.L.; Inskeep, P.B. J. Med. Chem. 1992, 35, 2169. Gadwood, R.C.; Kamdar, B.V.; Dubray, L.A.C.; Wolfe, M.L.; Smith, M.P.; Watt, W.; Mizsak, S.A.; Groppi, V.E. J. Med. Chem. 1993, 36, 1480. Atwal, K.S.; Grover, G.J.; Ahmed, S.Z.; Sleph, P.G.; Dzwonczyk, S.; Baird, A.J.; Normandin, D.E. J. Med. Chem. 1995, 38, 3236.
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J. Med. Chem.
, vol.38
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Atwal, K.S.1
Grover, G.J.2
Ahmed, S.Z.3
Sleph, P.G.4
Dzwonczyk, S.5
Baird, A.J.6
Normandin, D.E.7
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0030252582
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8. For previous reports of a benzopyran library synthesis see: Baldwin, J.J. Molecular Diversity, 1996, 2, 81.
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(1996)
Molecular Diversity
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Baldwin, J.J.1
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9544238081
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9. Cho, H.; Katoh, S.; Sayama, S.; Murakami, K.; Nakanishi, H.; Kajimoto, Y.; Ueno, H.; Kawasaki, H.; Aisaka, K.; Uchida, I. J. Med. Chem. 1996, 39, 3797.
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Cho, H.1
Katoh, S.2
Sayama, S.3
Murakami, K.4
Nakanishi, H.5
Kajimoto, Y.6
Ueno, H.7
Kawasaki, H.8
Aisaka, K.9
Uchida, I.10
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0010353070
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All compounds were characterized by ESIMS, NMR, and HPLC.
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10. All compounds were characterized by ESIMS, NMR, and HPLC.
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0028907801
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11. a) Look, G.C.; Murphy, M.M.; Campbell, D.A.; Gallop, M.A. Tetrahedron Lett. 1995, 36, 2937.
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Tetrahedron Lett.
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Look, G.C.1
Murphy, M.M.2
Campbell, D.A.3
Gallop, M.A.4
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85047670016
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b) Bray, A.M.; Chiefari, D.S.; Valerio, R.M.; Maeji, N.J. Tertrahedron Lett. 1995, 36, 5081.
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Tertrahedron Lett.
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Bray, A.M.1
Chiefari, D.S.2
Valerio, R.M.3
Maeji, N.J.4
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0029128552
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d) Boojamra, C.G.; Burow, K.M.; Ellman, J.A. J. Org. Chem. 1995, 60, 5742.
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Boojamra, C.G.1
Burow, K.M.2
Ellman, J.A.3
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0030200350
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12. Khan, N.M.; Arumugam, V.; Balasubramanian, S.; Tetrahedron Lett. 1996, 37, 4819.
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(1996)
Tetrahedron Lett.
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Khan, N.M.1
Arumugam, V.2
Balasubramanian, S.3
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0010306588
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note
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2 (4 eq) in pyridine for 24 h, followed by collection and concentration of the effluent.
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14. Johnson, C.R.; Zhang, B.; Fantauzzi, P.; Hocker, M.; Yager, K.M. Tetrahedron, 1998, 54, 4097.
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Tetrahedron
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Johnson, C.R.1
Zhang, B.2
Fantauzzi, P.3
Hocker, M.4
Yager, K.M.5
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