Optimized enzymatic synthesis of methyl benzoate in organic medium. Operating conditions and impact of different factors on kinetics

Biotechnology and Bioengineering

Volumn 60, Issue 3, 1998, Pages 356-361

  Leszczak, Jean Pierre ^a   Tran Minh, Canh ^a  

^a CENTRE SPIN   (France)

Author keywords

Enzymatic synthesis; Enzyme hydration; Methanol inhibition; Methyl benzoate; Solvent effects

Indexed keywords

AROMATIC COMPOUNDS; CARBOXYLIC ACIDS; CATALYSIS; CATALYST ACTIVITY; ENZYME INHIBITION; ESTERIFICATION; HYDRATION; METHANOL; ORGANIC SOLVENTS; REACTION KINETICS;

BENZOIC ACID; METHYL BENZOATE;

BIOSYNTHESIS;

BENZOIC ACID DERIVATIVE; ORGANIC COMPOUND; SOLVENT; TOLUENE; TRIACYLGLYCEROL LIPASE;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; ENZYME INHIBITION; ENZYME MECHANISM; ESTERIFICATION; HYDRATION; SYNTHESIS; WATER CONTENT;

CANDIDA RUGOSA;

EID: 0032487757     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19981105)60:3<356::AID-BIT12>3.0.CO;2-K     Document Type: Article

References (17)

1. Borzeix, F., Monot, F., Vandecasteele, J.-P. 1992. Strategies for enzymatic esterification in organic solvents: Comparison of microaqueous, biphasic, and micellar systems. Enzyme Microb. Technol. 14: 791-797.
2. Carta, G., Gainer, J. L., Benton, A. M. 1991. Enzymatic synthesis of esters using an immobilized lipase. Biotechnol. Bioeng. 37: 1004-1009.
3. Chulalaksananukul, W., Condoret, J.-S., Combes, D. 1993. Geranyl acetate synthesis by lipase-catalysed transesterification in supercritical carbon dioxide. Enzyme Microb. Technol. 15: 691-698.
4. Dordick, J. S. 1989. Enzymatic catalysis in monophasic organic solvents. Enzyme Microb. Technol. 11: 194-211.
5. Gillies, B., Yamazaki, H., Armstrong, D. W. 1987. Production of flavor esters by immobilized lipase. Biotechnol. Lett. 9(10): 709-714.
6. Goldberg, M., Thomas, D., Legoy, M.-D. 1990. The control of lipase-catalysed transesterification and esterification reaction rates. Eur. J. Biochem. 190: 603-609.
7. Gorman, L. A. S., Dordick, J. S. 1992. Organic solvents strip water off enzymes. Biotechnol. Bioeng. 39: 392-397.
8. Halling, P. J. 1990. Solvent selection for biocatalysis in mainly organic systems: Predictions of effects on equilibrium position. Biotechnol. Bioeng. 35: 691-701.
9. Klibanov, A. M. 1989. Enzymatic catalysis in anhydrous organic solvents. Trends Biochem. Sci. 14: 141-144.
10. Kodera, Y., Takahashi, K., Nishimura, H., Matshushima, A., Saito, Y., Inada, Y. 1986. Ester synthesis from α-substituted carboxylic acid catalysed by polyethyleneglycol-modified lipase from Candida cylindracea in benzene. Biotechnol. Lett. 8(12): 881-884.
11. Langrand, G., Rondot, N., Triantaphylides, C., Baratti, J. 1990. Short chain flavor esters synthesis by microbial lipases. Biotechnol. Lett. 12(8): 581-586.
12. Perraud, R., Moreau, L., Krahe, E. 1995. Optimierung der enzymkatalysierten Synthese von Methylacetat. Deut. Lebensm.-Rundsch. 91(7): 219-221.
13. Svensson, I., Wehtje, E., Adlercreutz, P., Mattiasson, B. 1994. Effect of water activity on reaction rates and equilibrium positions in enzymatic esterifications. Biotechnol. Bioeng. 44: 549-566.
14. Takahashi, K., Yoshimoto, T., Ajima, A., Tamaura, Y., Inada, Y. 1984. Modified lipoproteine lipase catalyses ester synthesis in benzene. Enzyme. 32: 235-240.
15. Tsujisaka, Y., Okumura, S., Iwai, M. 1977. Glyceride synthesis by four kinds of microbial lipase. Biochim. Biophys. Acta. 489: 415-422.
16. Yamane, T., Kojima, Y., Ichiryu, T., Nagata, M., Shimizu, S. 1989. Intramolecular esterification by lipase powder in microaqueous benzene: effect of moisture content. Biotechnol. Bioeng. 34: 838-843.
17. Zaks, A., Klibanov, A. M. 1988. Enzymatic catalysis in nonaqueous solvent. J. Biol. Chem. 263(7): 3194-3201.