Association of the insertion/deletion gene polymorphism of the apolipoprotein B signal peptide with myocardial infarction

Atherosclerosis

Volumn 141, Issue 1, 1998, Pages 167-175

  Gardemann, Andreas ^a   Ohly, Dorothea ^a   Fink, Monika ^a   Katz, Norbert ^a   Tillmanns, Harald ^a   Hehrlein, Friedrich Wilhelm ^b   Haberbosch, Werner ^c  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b Klin fur Herz und G   (Germany)

^c KERCKHOFF HEART CENTER   (Germany)

Author keywords

Apolipoprotein B; Apolipoprotein B signal peptide insertion deletion gene polymorphism; Cardiovascular disease; Myocardial infarction; Risk factors

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL; LIPOPROTEIN; SIGNAL PEPTIDE;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CORONARY ARTERY DISEASE; DNA POLYMORPHISM; GENE DELETION; GENE INSERTION; GENETIC VARIABILITY; GENOTYPE; HEART INFARCTION; HUMAN; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PEPTIDE ANALYSIS; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR;

ALLELES; APOLIPOPROTEINS B; CHOLESTEROL; CORONARY DISEASE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, GENETIC; PROTEIN SORTING SIGNALS; RISK FACTORS;

EID: 0032487604     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(98)00161-0     Document Type: Article

References (42)

1. Martin M.J., Hulley S.B., Browner W.S., Kuller L.H., Wentworth D. Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361662 men. Lancet. 2:1986;933-936.
2. Castelli W.P., Garrison R.J., Wilson P.W.F., Abbott R.D., Kalousdian S., Kannel W.B. Incidence of coronary heart disease and lipoprotein cholesterol levels: the Framingham Study. J. Am. Med. Assoc. 265:1986;2835-2838.
3. Cambien F., Warnet J.-M., Jacqueson A., Ducimetiere P., Richard J.L., Claude J.R. Relation of parental history of early myocardial infarction to the level of apolipoprotein B in man. Circulation. 76:1987;266-271.
4. Grundy S.M., Denke M.A. Dietary influences on serum lipids and lipoproteins. J. Lipid. Res. 31:1990;1149-1172.
5. Ornish D., Brown S.E., Scherwitz L.W., Billings J.H., Armstrong W.T., Ports T.A., McLanahan S.M., Kirkeeide R.L., Brans R.J., Gould G.L. Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial. Lancet. 336:1990;129-133.
6. Berg K. Steinberg A.G., Bearn A.G., Motulsky A.G., Childs B. Progress in medical genetics. 1983;35-90 Saunders, Philadelphia, PA.
7. Innerarity T.L., Mahley R.W., Weisgraber K.H., Bersot T.P., Krauss R.M., Vega G.L., Grundy S.M., Friedl W., Davignon J., McCarthy B.J. Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hyperlipoproteinemia. J. Lipid. Res. 31:1990;1337-1349.
8. Checovich W.J., Fitch W.L., Krauss R.M., Smith M.P., Rapacz J., Smith C.L., Attie A.D. Defective catabolism and abnormal composition of low-density lipoproteins from mutant pigs with hypercholesterolemia. Biochemistry. 27:1988;1934-1941.
9. Lowe S.W., Checovich W.J., Rapacz J., Attie A.D. Defective receptor binding of low density lipoprotein from pigs possessing mutant apolipoprotein B alleles. J. Biol. Chem. 263:1988;15467-15473.
10. Kesaniemi Y.A., Grundy S.M. Overproduction of low density lipoproteins associated with coronary heart disease. Arteriosclerosis. 3:1983;40-46.
11. Checovich W.J., Aiello R.J., Attie A.D. Overproduction of a buoyant low density lipoprotein subspecies in spontaneously hypercholesterolemic mutant pigs. Arterioscler. Thromb. 11:1991;351-361.
12. Boerwinkle E., Chan L. A three codon insertion/deletion polymorphism in the signal peptide region of the human apolipoprotein B (APOB) gene directly typed by the polymerase chain reaction. Nucleic. Acid. Res. 17:1989;4003.
13. Turner P.R., Talmud P.J., Visvikis S., Ehnholm C., Tiret L. DNA polymorphisms of the apoprotein B gene are associated with altered plasma lipoprotein concentrations but not with perceived risk of cardiovascular disease: European Atherosclerosis Research Study. Atherosclerosis. 116:1995;221-234.
14. Corbo R.M., Vilardo T., Mantuano E., Ruggeri M., Gemma A.T., Scacchi R. Apolipoproteins B and E, and angiotensin I-converting enzyme (ACE) genetic polymorphisms in Italian women with coronary artery disease (CAD) and their relationships with plasma lipid and apolipoprotein levels. Clin. Genet. 52:1997;77-82.
15. Zaman M.M., Ikemoto S., Yoshiike N., Date C., Yokoyama T., Tanaka H. Association of apolipoprotein genetic polymorphisms with plasma cholesterol in a Japanes rural population. The Shibata Study. Arterioscler. Thopmb. Vasc. Biol. 17:1997;3495-3504.
16. Glisic S., Prljic J., Radovanovic N., Alavantic D. Study of apoB gene signal peptide insertion/deletion polymorphism in a healthy Serbian population: no association with serum lipid levels. Clin. Chim. Acta. 263:1997;57-65.
17. Hixson J.E., McMahan A., McGill H.C. Jr., Strong J.P. ApoB insertion/deletion polymorphisms are associated with atherosclerosis in young black but not young white males. Arterioscler. Thromb. 12:1992;1023-1029.
18. Peacock R., Dunning A., Hamsten A., Tornvall P., Humphries S., Talmud P. Apolipoprotein B gene polymorphisms, lipoproteins and coronary atherosclerosis: a study of young myocardial infarction survivors and healthy population-based individuals. Atherosclerosis. 92:1992;151-164.
19. Shadrina M.I., Slonimskii P.A., Oganov R.G., Perova N.V., Limborskaia S.A. Analysis of polymorphism of the 5′-terminal region of apolipoprotein B gene in patients with ischemic heart disease. Genetika. 32:1996;1041-1044.
20. Ye P, Chen BS, Wang SW. Apolipoprotein B signal peptide insertion/deletion polymorphism in Chines patients with coronary heart disease. Chung Hua I Hsueh Tsa Chih 1994;341-344.
21. Hong S.H., Lee C.C., Kim J.Q. Genetic variation of the apolipoprotein B gene in Korean patients with coronary artery disease. Mol. Cells. 7:1997;521-525.
22. Marshall H.W., Morrison L.C., Wu L.L., Anderson J.L., Corneli P.S., Stauffer D.M., Allen A., Karagounis L.A., Ward R.H. Apolipoprotein polymorphisms fail to define risk of coronary artery disease. Results of a prospective, angiographically controlled study. Circulation. 89:1994;567-577.
23. Visvikis S., Cambou J.P., Arveiler D., Evans A.E., Parra H.J., Aguillon D., Fruchart J.C., Siest G., Cambien F. Apolipoprotein B signal peptide polymorphism in patients with myocardial infarction and controls. Hum. Genet. 90:1993;561-565.
24. Bohn M., Bakken A., Eriksson J., Berg K. The apolipoprotein B signal peptide insertion/deletion polymorphism is not associated with myocardial infarction in Norway. Clin. Genet. 45:1994;255-259.
25. Gensini G.G. Coronary arteriography. Braunwald E. Heart disease. 1980;352-353 Saunders, Philadelphia, PA.
26. Gensini G.G. A more meaningful scoring system for determining the severity of coronary heart disease. Am. J. Cardiol. 51:1983;606.
27. Fossati P., Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin. Chem. 82:1982;2077-2080.
28. Kattermann R., Jaworek D., Moller G., Assmann G., Bjorkhem I., Svensson L., Borner K., Boerma G., Leijnse B., Desager J.P. Multicenter study of a new enzymatic method of cholesterol determination. Clin. Chem. Clin. Biochem. 22:1984;245-251.
29. Fink P.C., Romer M., Haeckel R., Fateh-Moghadam A., Delanghe J., Gressner A.M., Dubs R.W. Measurement of proteins with the Behring nephelometer. A multicenter evaluation. J. Clin. Chem. Clin. Biochem. 27:1989;261.
30. Clauss A. Rapid physiological coagulation method in determination of fibrinogen. Acta. Haematol. (Basel). 17:1957;237.
31. Kawasaki E.S. Sample preparation from blood, cells, and other fluids. Innis M.A., Gelfand D.H., Sninsky J.J., White T.J. PCR protocols: A guide to methods and applications. 1990;146-152 Academic Press, San Diego, CA.
32. Visvikis S., Chan L., Siest G., Drouin P., Boerwinkle E. An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene. Hum. Genet. 84:1990;373-375.
33. Rigat B., Hubert C., Alhenc-Gelas F., Cambien F., Corvol P., Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J. Clin. Invest. 86:1990;1343-1346.
34. Lindpaintner K., Pfeffer M.A., Kreutz R., Stampfer M., Grodstein F., La Motte F., Buring J., Hennekens C.H. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N. Engl. J. Med. 332:1995;706-711.
35. Sturley S.L., Talmud P.J., Brasseur R., Culbertson M.R., Humphries S.E., Attie A.D. Human apolipoprotein B signal sequence variants confer a secretion-defective phenotype when expressed in yeast. J. Biol. Chem. 34:1994;21670-21675.
36. Xu C.F., Tikkanen M.J., Huttunen J.K., Pietinen P., Butler R., Humphries S., Talmud P. Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels. J. Lipid. Res. 31:1990;1255-1261.
37. Boerwinkle E., Chen S.-H., Visvikis S., Hanis C.L., Siest G., Chan L. Signal peptide length variation in human apolipoprotein B gene: Molecular characteristics and association with plasma glucose levels. Diabetes. 40:1991;1539-1544.
38. Cambien F., Poirier O., Lecerf L., Evans A., Cambou J.P., Arveiler D., Luc G., Bard J.M., Bara L., Ricard S., Tiret L., Amouyel P., Alhenc-Gelas F., Soubrier F. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature. 359:1992;641-644.
39. Gardemann A., Schwartz O., Weiß T., Katz N., Eberbach A., Hehrlein W., Tillmanns G., Waas W., Haberbosch W. Gene polymorphism but not catalytic activity of angiotensin I-converting enzyme is associated to coronary artery disease and myocardial infarction in low risk patients. Circulation. 92:1995;2796-2799.
40. Agerholm-Larsen B., Nordestgaard B.G., Steffensen R., Sorensen T.I.A., Jensen G., Tybjaerg-Hansen A. ACE gene polymorphism: Ischemic heart disease and longevity in 10150 individuals. A case-referent and retrospective cohort study based on the Copenhagen City Heart Study. Circulation. 95:1997;2358-2367.
41. Singer D.R.J., Missouris C.G., Jeffery S. Angiotensin-converting enzyme gene polymorphism. What to do about all the confusion? Circulation. 94:1996;236-239.
42. Samani N.J., Thompson J.R., O'Toole L., Channer K., Woods K.L. A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme with myocardial infarction. Circulation. 94:1996;708-712.