Enantiospecific nucleophilic substitution of the dimethylamino group in (R)-tricarbonyl[-{(1-dimethylamino)ethyl}-η6benzene]chromium

Tetrahedron Asymmetry

Volumn 9, Issue 11, 1998, Pages 1867-1870

  Englert, Ulli ^a   Salzer, Albrecht ^a   Vasen, Daniela ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROFORMIC ACID ETHYL ESTER; PHENETHYLAMINE DERIVATIVE; TRICARBONYL[[(1 DIMETHYLAMINO)ETHYL] ETA6 BENZENE]CHROMIUM; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENANTIOMER; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS;

EID: 0032486293     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(98)00192-X     Document Type: Article

References (25)

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11. 3).
12. 12. For a review see: Cooley, J. H.; Evain, E. J. Synthesis 1989, 1-7.
13. 13. Column: CHIRALCEL OD; eluent: hexane:i-propanol (9:1).
14. 14. Intensity data were collected at -70°C on a CAD4 diffractometer with the ω/2θ mode using graphite monochromated CuKα radiation, λ=1.54184 Å. Further details on the structure determination are available from the Cambridge Crystallographic Data Center, CSD-xxxxxx.
15. w=0.050, GOF=1.100.
16. w=0.099.
17. 6, 202 MHz) δ +10.39.
18. 31P-NMR data of the (R,S)-diastereomer: +50.16 ppm.
19. 19. Intensity data were collected at -70°C on a CAD4 diffractometer with the ω mode using graphite monochromated MoKα radiation, λ=0.71073 Å. Further details on the structure determination are available from the Cambridge Crystallographic Data Center, CSD-xxxxxx.
20. w=0.031, GOF=0.801.
21. 25 obtained was 0.006(16).
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