Prognostic value of mutations and a germ line polymorphism of the p53 gene in non-small cell lung carcinoma: Association with clinicopathological features

Cancer Letters

Volumn 128, Issue 1, 1998, Pages 93-99

  Tagawa, Masatoshi ^a   Murata, Motoi ^a   Kimura, Hideki ^a  

^a CHIBA CANCER CENTER   (Japan)

Author keywords

Non small cell lung carcinoma; p53; Polymorphism; Prognosis; Single strand conformation polymorphism

Indexed keywords

ARGININE; DNA; PROLINE; PROTEIN P53;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE MUTATION; GERM LINE; HETEROZYGOTE; HISTOPATHOLOGY; HOMOZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CARCINOMA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; SMOKING; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; AGED; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; FEMALE; GENES, P53; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROGNOSIS; SMOKING;

EID: 0032486222     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00056-1     Document Type: Article

References (27)

1. Hollstein M., Sidransky D., Vogelstein B., Harris C.C. p53 mutations in human cancers. Science. 253:1991;49-53.
2. Fontanini G., Vignati S., Bigini D., Merlo G.R., Ribecchini A., Angeletti C.A., Basolo F., Pingitore R., Bevilacqua G. Human non-small cell lung cancer: p53 protein accumulation is an early event and persists during metastatic progression. J. Pathol. 174:1994;23-31.
3. Lowe S.W., Ruley H.E., Jacks T., Housman D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74:1993;957-967.
4. O'Connor P.M., Jackman J., Jondle D., Bhatia K., Magrath I., Kohn K.W. Role of p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res. 53:1993;4776-4780.
5. Suzuki H., Takahashi T., Kuroishi T., Suyama M., Ariyoshi Y., Takahashi T., Ueda R. p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. Cancer Res. 52:1992;734-736.
6. Chiba I., Takahashi T., Nau M.M., D'Amico D., Curiel D.T., Mitsudomi T., Buchhagen D.L., Carbone D., Piantadori S., Koga H., Reissman P.T., Slamon D.J., Holmes E.C., Minna J.D. Mutations in the p53 gene are frequent in primary, resectable non-small cell lung cancer. Oncogene. 5:1990;1603-1610.
7. Kishimoto Y., Murakami Y., Shiraishi M., Hayashi K., Sekiya T. Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung. Cancer Res. 52:1992;4799-4804.
8. McLaren R., Kuzu I., Dunnill M., Harris A., Lane D., Gatter K.C. The relationship of p53 immunostaining to survival in carcinoma of the lung. Br. J. Cancer. 66:1992;735-738.
9. Horio Y., Takahashi T., Kuroishi T., Hibi K., Suyama M., Niimi T., Shimokata K., Yamakawa K., Nakamura Y., Ueda R., Takahashi T. Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer. Cancer Res. 53:1993;1-4.
10. Marchetti A., Buttitta F., Merlo G., Diella F., Pellegrini S., Pepe S., Macchiarini P., Chella A., Angeletti C.A., Callahan R., Bistocchi M., Squartini F. p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. Cancer Res. 53:1993;2846-2851.
11. Mitsudomi T., Oyama T., Kusano T., Osaki T., Nakanishi R., Shirakusa T. Mutation of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer. J. Natl. Cancer Inst. 85:1993;2018-2023.
12. Ebina M., Steinberg S.M., Mulshine J.L., Linnoila R.I. Relationship of p53 overexpression and up-regulation of proliferative cell nuclear antigen with the clinical course of non-small cell lung cancer. Cancer Res. 54:1994;2496-2503.
13. Passlick B., Izbicki J.R., Riethmüller G., Pantel K. p53 in non-small-cell lung cancer. J. Natl. Cancer Inst. 86:1994;801-802.
14. Xu H.-J., Quinlan D.C., Davidson A.G., Hu S.-X., Summers C.L., Li J., Benedict W.F. Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma. J. Natl. Cancer Inst. 86:1994;695-699.
15. Fong K.M., Kida Y., Zimmerman P.V., Ikenaga M., Smith P.J. Loss of heterozygosity frequently affects chromosome 17q in non-small cell lung cancer. Cancer Res. 55:1995;4268-4272.
16. Fontanini G., Vignati S., Bigini D., Mussi A., Lucchi M., Angeletti C.A., Basolo F., Bevilacqua G. Bcl-2 protein: a prognostic factor inversely correlated to p53 in non-small-cell lung cancer. Br. J. Cancer. 71:1995;1003-1007.
17. Kashii T., Mizushima Y., Lima C.E.Q., Noto H., Sato H., Saito H., Kusajima M., Yamamoto K., Kobayashi M. Studies on clinicopathological features of lung cancer patients with K-ras/p53 gene alterations: comparison between younger and older groups. Oncology. 52:1995;219-225.
18. Lee J.S., Yoon A., Kalapurakal S.K., Ro J.Y., Lee J.J., Tu N., Hittelman W.N., Hong W.K. Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor. J. Clin. Oncol. 13:1995;1893-1903.
19. Kawajiri K., Nakachi K., Imai K., Watanabe J., Hayashi S. Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer. Carcinogenesis. 14:1993;1085-1089.
20. Jim X., Wu X., Roh J.A., Amos C.I., King T.M., Branch C., Honn S.E., Spitz M.R. Higher lung cancer risk for younger African-Americans with the Pro/Pro p53 genotype. Carcinogenesis. 16:1995;2205-2208.
21. Murata M., Tagawa M., Kimura M., Kimura H., Watanabe S., Saisho H. Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history. Carcinogenesis. 17:1996;261-264.
22. World Health Organization The World Health Organization. Histological typing of lung tumors. Am. J. Clin. Pathol. 77:1982;123-136.
23. Mountain C.F. A new international staging system for lung cancer. Chest. 89:1986;225S-233S.
24. Murakami Y., Hayashi K., Sekiya T. Detection of aberrations of the p53 alleles and the gene transcript in human tumor cell lines by single-strand conformation polymorphism analysis. Cancer Res. 51:1991;3356-3361.
25. Levine A.J., Perry M.E., Chang A., Silver A., Dittmer D., Wu M., Welsh D. The 1993 Walter Hubert lecture: the role of tumor-suppressor gene in tumorigenesis. Br. J. Cancer. 69:1994;409-416.
26. Bodner S.M., Minna J.D., Jensen S.M., D'Amico D., Carbone D., Mitsudomi T., Fedorko J., Buchhagen D.L., Nau M.M., Gazdar A.F., Linnoila R.I. Expression of p53 proteins in lung cancer correlates with the class of p53 gene mutation. Oncogene. 7:1992;743-749.
27. Jacks T., Weinberg R.A. Cell-cycle control and its watchman. Nature. 381:1996;643-644.