Lipase mediated preparation of differently protected homochiral 2-aryl- 2-fluoro-1,3-propanediols

Tetrahedron Asymmetry

Volumn 9, Issue 11, 1998, Pages 1859-1862

  Guanti, Giuseppe ^a   Narisano, Enrica ^a   Riva, Renata ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARYL 2 FLUORO 1,3 PROPANEDIOL; 2 ARYL 2 FLUOROMALONIC ACID; MALONIC ACID DERIVATIVE; PROPANEDIOL DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CHEMICAL REACTION; CHIRALITY; ENANTIOMER; HYDROLYSIS; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0032486153     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(98)00181-5     Document Type: Article

References (20)

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12. 3H): 84.40 (s) for 1b, 78.53 (s) for 1c.
13. 9. (a) Lal, G. S. J. Org. Chem. 1993, 55, 2791-2796.
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15. 10. Guanti, G.; Banfi, L.; Riva, R. Tetrahedron: Asymmetry 1995, 6, 1345-1356.
16. 19F) as the internal standard.
17. 11 93.66-94.76 (m) for 3a, 96.70-97.76 (m) for 3b.
18. 11 84.09 (s) for 2a, 84.21 (s) for 2b, 78.31 (s) for 2c, 94.57-95.64 (m) for 4a, 93.80-94.94 (m) for 4b.
19. 14. Goj, O.; Burchardt, A.; Haufe, G. Tetrahedron: Asymmetry 1997, 8, 399-408.
20. 15. Every new compound was fully characterised and gave satisfactory analytical data.