Reaction of dopa decarboxylase with α-methyldopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active site directed affinity label

Biochemistry

Volumn 37, Issue 18, 1998, Pages 6552-6561

  Bertoldi, Mariarita ^a   Dominici, Paola ^a   Moore, Patrick S ^a   Maras, Bruno ^b   Borri Voltattorni, Carla ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; METHYLDOPA;

ANTIHYPERTENSIVE ACTIVITY; ARTICLE; DECARBOXYLATION; DOPAMINE METABOLISM; DRUG MECHANISM; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INACTIVATION; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; TRANSAMINATION;

ACETONE; AFFINITY LABELS; BINDING SITES; CIRCULAR DICHROISM; DEAMINATION; DOPA DECARBOXYLASE; KINETICS; METHYLDOPA; OXIDATION-REDUCTION; PROTEIN CONFORMATION; PYRIDOXAL PHOSPHATE; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY, ATOMIC;

FELIS CATUS;

EID: 0032485922     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9718898     Document Type: Article

References (28)

1. Oates, J. A. (1966) in The Pharmacological Basis of Therapeutics (Hardman, J. G., Goodman Gilman, A., and Limbird, L. E., Eds.) 9th ed., pp 780-808, McGraw-Hill, London.
2. Weissbach, H., Lovenberg, W., and Udenfriend, S. (1966) Biochem. Biophys. Res. Commun. 3, 225-227.
3. Sourkes, T. L. (1971) Nature 229, 413-414.
4. Lovenberg, W., Barchas, J., Weissbach, H., and Udenfriend, S. (1963) Arch. Biochem. Biophys. 103, 9-14.
5. Smith, S. (1960) Br. J. Pharmacol. 15, 319-327.
6. Borri Voltattomi, C., Minelli, A., and Turano, C. (1971) FEBS Lett. 17, 231-235.
7. O'Leary, M., and Baughn, R. L. (1977) J. Biol. Chem. 252, 7168-7173.
8. Barboni, E., Borri Voltattomi, C., D'Erme, M., Fiori, A., Minelli, A., Rosei, M. A., and Turano, C. (1981) Biochem. Biophys. Res. Commun. 99, 576-583.
9. Bertoldi, M., Moore, P. S., Maras, B., Dominici, P., and Borri Voltattomi, C. (1996) J. Biol. Chem. 271, 23954-23959.
10. Slates, H. L., Taub, D., Kuo, C. H., and Wendler, N. L. (1964) J. Org. Chem. 29, 1424-1429.
11. Moore, P. S., Dominici, P., and Borri Voltattomi, C. (1996) Biochem. J. 315, 249-256.
12. Dominici, P., Moore, P. S., and Borri Voltattomi, C. (1993) Biochem. J. 295, 493-500.
13. Sherald, A. F., Sparrow, J. C., and Wright, T. R. F. (1973) Anal. Biochem. 56, 300-305.
14. Charteris, A., and John, R. A. (1975) Anal. Biochem. 66, 365-371.
15. Bossa, F., and Barra, D. (1968) Ital. J. Biochem. 17, 285-291.
16. Ueno, H., Likos, J. J., and Metzler, D. E. (1982) Biochemistry 21, 4387-4393.
17. Likos, J. J., Ueno, H., Feldhaus, R. W., and Metzler, D. E. (1982) Biochemistry 21, 4377-4386.
18. Ahmed, S. A., Ruvinov, S. B., Kayastha, A. M., and Miles, E. W. (1991) J. Biol. Chem. 266, 21548-21557.
19. Maras, B., Dominici, P., Barra, D., Bossa, F., and Borri Voltattomi, C. (1991) Eur. J. Biochem. 201, 385-391.
20. Au, W. Y. W., Dring, L. G., Grahame-Smith, D. G., Isaac, P., and Williams, R. T. (1972) Biochem. J. 129, 1-10.
21. Porter, C. C., and Titus, D. C. (1963) J. Pharmacol. Exp. Ther. 139, 77-87.
22. Minelli, A., Charteris, A. T., Borri Voltattomi, C., and John, R. A. (1979) Biochem. J. 183, 361-368.
23. Tancini, B., Dominici, P., Simmaco, M., Schininà, M. E., Barra, D., and Borri Voltattomi, C. (1988) Arch. Biochem. Biophys. 260, 569-576.
24. Badet, B., Roise, D., and Walsh, C. T. (1984) Biochemistry 23, 5188-5194.
25. Roise, D., Soda, K., Yagi, T., and Walsh, C. T. (1984) Biochemistry 23, 5195-5201.
26. Silverman, R. B., and George, C. (1988) Biochem. Biophys. Res. Commun. 150, 942-946.
27. Bhattacharjee, M. K., and Snell, E. E. (1990) J. Biol. Chem. 265, 6664-6668.
28. Schnackerz, K. D., Ehrlich, J. H., Giesemann, W., and Reed, T. A. (1979) Biochemistry 18, 3557-3563.