Convenient synthesis of 1-alkyl-2,5-bis(thiophenylmethylene)pyrroles using the mannich reaction

Tetrahedron Letters

Volumn 39, Issue 10, 1998, Pages 1087-1090

  Kim, In Tae ^a   Elsenbaumer, Ronald L ^a  

^a UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 ALKYL 2,5 BIS(THIOPHENYLMETHYLENE)PYRROLE DERIVATIVE; POLYMER; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; METHYLATION; REACTION ANALYSIS;

EID: 0032485438     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10786-9     Document Type: Article

References (12)

1. 1. Kim, I. T.; Elsenbaumer, R. L., Synth. Met. 1997, 85, 1345-1346.
2. 2. Diaz, A. F.; Kanazawa, K. K., J. Chem. Soc. Chem. Commun. 1979, 635-636.
3. 3. Kovacic, P.; Khoury, P.; Elsenbaumer, R. L., Synth. Met. 1983, 6, 31-38.
4. 4. Clauson-Kaas, N.; TyIe, Z., Acta Chem. Scand. 1952, 6, 962-963.
5. 5. Kreutzberger, A.; Kalter, A., J. Org. Chem 1960, 25, 554-556.
6. 6. Treibs, A.; Hitzler, O., Chem. Ber. 1957, 90, 787-788.
7. 7. Fegley, M. F.; Bortnick, N. M.; McKeever, C. H., J. Amer. Chem. Soc. 1957, 79, 4140-4144.
8. 8. Murahashi, S. I.; Shimamura, T.; Moritani, I., J. Chem. Soc. Chem. Comm. 1974, 93-932.
9. 9. Bachman, G. B.; Heisey, L. V., J. Amer. Chem. Soc. 1946, 68, 2496-2499.
10. 10. Heaney, H.; Papageorgiou, G.; Wilkins, R. F., J. Chem. Soc. Chem. Commun. 1988, 1161-1163.
11. 11. Lumma, W. C.; Baldwin, J.J. Jr.; Bicking, B.; Bolhofer, W. A.; Hoffman, J. M.; Phillips, B. T.; Robb, C. M.; Torchiana, M. L.; Schlegel, H.B.; Smith, G. M.; Hirshfield, J. M., J. Med. Chem. 1984, 27, 1047-1052.
12. 2 : C, 63.83; H, 5.35; N, 3.91; S, 17.90. Found: C, 63.70; H, 5.35; N, 3.81; S, 18.00.