Interaction between peroxynitrite and L-cysteine: Effects on rat aorta

European Journal of Pharmacology

Volumn 344, Issue 2-3, 1998, Pages 183-190

  Dowell, Fiona J ^a   Martin, William ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Aorta, rat; L Cysteine; Nitric oxide (NO); Peroxynitrite; S Nitrosothiol; Vasodilatation

Indexed keywords

CYSTEINE; NITRIC OXIDE; NITROSO DERIVATIVE; PEROXYNITRITE; THIOL DERIVATIVE;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; AORTA; ARTICLE; DRUG HALF LIFE; DRUG POTENCY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 0032485403     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01598-7     Document Type: Article

References (19)

1. Beckman, J.S., Beckman, T.W., Chen, J., Marshall, P.A., Freeman, B.A., 1990. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87, 1620-1624.
2. Beckman, J.S., Ze, Y.Z., Anderson, P.G., Chen, J., Accavitti, M.A., Tarpey, M.M., White, C.R., 1994. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol. Chem. 375, 81-88.
3. Davidson, C.A., Kaminski, P.M., Wu, M., Wolin, M.S., 1996. Nitrogen dioxide causes pulmonary arterial relaxation via thiol nitrosation and NO formation. Am. J. Physiol. 270, H1038-H1043.
4. Dowell, F.J., Martin, W., 1997. The effects of peroxynitrite on rat aorta: Interaction with glucose and related substances. Eur. J. Pharmacol. 338, 43-53.
5. Feelisch, M., 1991. The biochemical pathways of nitric oxide formation from nitrovasodilators: Appropriate choice of NO donors and aspects of preparation and handling of aqueous NO solutions. J. Cardiovasc. Pharmacol. 17, S25-S33.
6. Furchgott, R.F., Jothianandan, D., 1996. The influence of glucose in the bathing solution on the response of rings of rabbit aorta to peroxyni trite. In: Moncada, S., Stamler, J., Gross, S., Higgs, A.E. (Eds.), Biology of Nitric Oxide, Part 5. Portland Press, London, p. 12.
7. Kaur, H., Halliwell, B., 1994. Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. FEBS Lett. 350, 9-12.
8. Liu, S., Beckman, J.S., Ku, D.D., 1994. Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs. J. Pharmacol. Exp. Ther. 268, 1114-1121.
9. Martin, W., Furchgott, R.F., Villani, G.M., Jothianandan, D., 1986. Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor (EDRF). J. Pharmacol. Exp. Ther. 237, 529-538.
10. Mayer, B., Schrammel, A., Klatt, P., Koesling, D., Schmidt, K., 1995. Peroxynitrite-induced accumulation of cyclic GMP in endothelial cells and stimulation of purified soluble guanylyl cyclase. Dependence on glutathione and possible role of S-nitrosation. J. Biol. Chem. 270, 17355-17360.
11. Moncada, S., Rees, D.D., Schulz, R., Palmer, R.M.J., 1991. Development and mechanism of a specific supersensitivity to nitrovasodilators following inhibition of vascular nitric oxide synthesis in vivo. Proc. Natl. Acad. Sci. USA 88, 2166-2170.
12. Moro, M.A., DarleyUsmar, V.M., Goodwin, D.A., Read, N.G., Zamorapino, R., Feelisch, M., Radomski, M.W., Moncada, S., 1994. Paradoxical fate and biological action of peroxynitrite on human platelets. Proc. Natl. Acad. Sci. USA 91, 6702-6706.
13. Moro, M.A., DarleyUsmar, V.M., Lizasoain, I., Su, Y., Knowles, R.G., Radomski, M.W., Moncada, S., 1995. The formation of nitric oxide donors from peroxynitrite. Br. J. Pharmacol. 116, 1999-2004.
14. Radi, R., Beckman, J.S., Bush, K.M., Freeman, B.A., 1991. Peroxynitrite oxidation of sulfhydryls: The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266, 4244-4250.
15. Soszynski, M., Bartosz, G., 1996. Effect of peroxynitrite on erythrocytes. Biochim. Biophys. Acta 1291, 107-114.
16. Van der Vliet, A., Smith, D., O'Neill, C.A., Kaur, H., DarleyUsmar, V., Cross, C.E., Halliwell, B., 1994. Interactions of peroxynitrite with human plasma and its constituents: Oxidative damage and antioxidant depletion. Biochem. J. 303, 295-301.
17. Villa, L.M., Salas, E., DarleyUsmar, V.M., Radomski, M.W., Moncada, S., 1994. Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc. Natl. Acad. Sci. USA 91, 12383-12387.
18. Wang, P., Zweier, J.L., 1996. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart: Evidence for peroxynitritemediated reperfusion injury. J. Biol. Chem. 271, 29223-29230.
19. Wu, M., Pritchard Jr., K.A., Kaminski, P.M., Fayngersh, R.P., Hintze, T.H., Wolin, M.S., 1994. Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite. Am. J. Physiol. 266, H2108-H2113.