Roles of acid/base nature and molecular weight in drug release from matrices of gelfoam and monoisopropyl ester of poly(vinyl methyl ether-maleic anhydride)

Journal of Controlled Release

Volumn 56, Issue 1-3, 1998, Pages 273-283

  Hämäläinen, Kaisa Mari ^a,b   Määttä, Elsi ^a   Piirainen, Hilkka ^a   Marianne Sarkola, ^a   Väisänen, Anne ^a   Ranta, Veli Pekka ^a   Urtti, Arto ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b ORION CORPORATION   (Finland)

Author keywords

Diffusion; Drug release; Gelfoam ; Ocular drug delivery; Ocular insert; Poly(vinyl methyl ether maleic anhydride); Polymer erosion

Indexed keywords

AGENTS ACTING ON THE EYE; CARBOXYFLUORESCEIN; DEXTRAN; FUROSEMIDE; GELFOAM; LEUCINE ENKEPHALINAMIDE; MACROGOL; MANNITOL; METENKEPHALINAMIDE; N (1 CARBOXY 3 PHENYLPROPYL)PHENYLALANYLISOSERINE; PYRAN COPOLYMER; SALICYLATE SODIUM; TIMOLOL; TIMOLOL MALEATE;

ARTICLE; DIFFUSION; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; IN VITRO STUDY; ISOTOPE LABELING; MOLECULAR WEIGHT; PRIORITY JOURNAL;

BUFFERS; CONJUNCTIVA; DELAYED-ACTION PREPARATIONS; DEXTRANS; ESTERS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCEINS; FUROSEMIDE; GELATIN SPONGE, ABSORBABLE; HYDROGEN-ION CONCENTRATION; MALEATES; MANNITOL; MOLECULAR WEIGHT; OPHTHALMIC SOLUTIONS; POLYETHYLENES; SCLERA; TIMOLOL;

EID: 0032484236     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00094-7     Document Type: Article

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