Poly(vinyl alcohol) nanoparticles prepared by freezing-thawing process for protein/peptide drug delivery

Journal of Controlled Release

Volumn 56, Issue 1-3, 1998, Pages 117-126

  Li, Jia Kui ^a   Wang, Nuo ^a   Wu, Xue Shen ^a,b  

^a LONG ISLAND UNIVERSITY   (United States)

^b POLYTECHNIC UNIVERSITY   (United States)

Author keywords

Freezing thawing process; Hydrogel; Nanoparticles; Poly(vinyl alcohol); Protein peptide drug delivery

Indexed keywords

BOVINE SERUM ALBUMIN; NANOPARTICLE; POLYVINYL ALCOHOL;

ARTICLE; DRUG RELEASE; DRUG STABILITY; EMULSION; FREEZING; HYDROGEL; MICROSCOPY; PARTICLE SIZE; PERCEPTION; PRIORITY JOURNAL; TECHNIQUE; TEMPERATURE; THAWING;

CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; DRUG CARRIERS; DRUG STABILITY; EMULSIONS; FREEZING; HYDROGELS; PARTICLE SIZE; POLYVINYL ALCOHOL; PROTEINS; SERUM ALBUMIN, BOVINE;

EID: 0032484158     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00089-3     Document Type: Article

References (21)

1. Sad W. Protein drugs: a revolution in therapy? Pharm. Res. 3:1986;3-6.
2. Lee V.H. Peptide and protein drug delivery: opportunities and challenges. Pharm. Inter. 7:1986;208-212.
3. Hyon S.H., Cha W.I., Ikada Y., Kita M., Ogura Y., Honda Y. Poly(vinyl alcohol) hydrogels as soft contact lens material. J. Biomater. Sci. Polym. Ed. 5:1994;397-406.
4. Juang J.H., Bonner W.S., Ogawa Y.J., Vacanti P., Weir G.C. Outcome of subcutaneous islet transplantation improved by polymer device. Transplantation. 61:1996;1557-1561.
5. Chen D.H., Leu J.C., Huang T.C. Transport and hydrolysis of urea in a reactor-separator combining an anion-exchange membrane and immobilized urease. J. Chem. Technol. Biotechnol. 61:1994;351-357.
6. Korsmeyer R.W., Peppas N.A. Effect of the morphology of hydrophilic polymeric matrices on its diffusion and release of water soluble drugs. J. Membr. Sci. 9:1981;211-227.
7. Basmadjian D.M., Sefton V. Relationship between release rate and surface concentration for heparinised materials. J. Biomed. Mater. Res. 17:1983;509-518.
8. Colombo P., Caramella C., Conte U., Gazzaniga A., La Manna A. Surface crosslinking of compressed polymeric mini-matrices for drug release control. J. Controlled Rel. 1:1985;283-289.
9. Thanoo B.C., Sunny M.C., Jayakrishnan A. Controlled release of oral drugs from cross-linked polyvinyl alcohol microspheres. J. Pharm. Pharmacol. 45:1993;16-20.
10. Carstensen J.T., Marty J.P., Puisieux F., Fessi H. Bonding mechanisms and hysteresis areas in compression cycle plots. J. Pharm. Sci. 70:1981;222-223.
11. Peppas N.A. Turbidimetric studies of aqueous poly(vinyl alcohol) solutions. Makromol. Chem. 176:1975;3433-3440.
12. Yokoyama F., Masada I., Shimamura K., Ikawa T., Monobe K. Morphology and structure of highly elastic poly(vinyl alcohol) hydrogel prepared by repeated freezing-and-melting. Coll. Polym. Sci. 264:1986;559-561.
13. Ficek B.J., Peppas N.A. Novel preparation of poly(vinyl alcohol) microparticles without crosslinking agent for controlled drug delivery of proteins. J. Controlled Rel. 27:1993;259-264.
14. Wang N., Wu X.S. Preparation and characterization of agarose hydrogel nanoparticles for protein and peptide drug delivery. Pharm. Dev. Tech. 2:1997;135-142.
15. Li J.K., Wang N., Wu X.S. Gelatin nanoencapsulation of protein and peptide drug by using an emulsifier free emulsion method. J. Microencapsulation. 15:1998;1-10.
16. Arshady R. Albumin microspheres and microcapsules: methodology of manufacturing techniques. J. Controlled Rel. 14:1990;111-131.
17. Tabata Y., Gutta S., Langer R. Controlled delivery systems for proteins using polyanhydride microspheres. Pharm. Res. 10:1993;487-496.
18. Soriano I., Llabres M., Evora C. Release control of albumin from polylactic acid microspheres. Int. J. Pharm. 125:1995;223-230.
19. Peppas N.A., Stauffer S.R. Reinforced uncrosslinked poly(vinyl alcohol) gels produced by cyclic freezing-thawing processes: a short review. J. Controlled Rel. 16:1991;305-310.
20. Urushizaki F., Yamaguchi H., Nakamura K., Numajiri S., Sugibayashi K., Morimoto Y. Swelling and mechanical properties of poly(vinyl alcohol) hydrogels. Int. J. Pharm. 58:1990;135-142.
21. Lee P.I. Kinetics of drug release from hydrogel matrices. J. Controlled Rel. 2:1985;277-288.