Methods for quantitative determination of drug localized in the skin

Journal of Controlled Release

Volumn 56, Issue 1-3, 1998, Pages 7-21

  Touitou, Elka ^a   Meidan, Victor M ^a   Horwitz, Ehud ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Drug distribution; Drug localization; Drug quantitation in skin; Methodologies; Quantitative autoradiography; Skin

Indexed keywords

ACETYLSALICYLIC ACID; BENZOIC ACID; CAFFEINE; CARBON 13; CARBOXYFLUORESCEIN; CIMETIDINE; CYCLOSPORIN A; DITHRANOL; ECONAZOLE; FLUOROURACIL; FLUTRIMAZOLE; GLYCINE; HYDROCORTISONE; IBUPROFEN; OLEIC ACID; PARATHION; PIROXICAM; RETINOID; TETRAHYDROCANNABINOL; TRIAMCINOLONE ACETONIDE;

AUTORADIOGRAPHY; CALIBRATION; CHROMATOGRAPHY; DRUG DETERMINATION; DRUG TISSUE LEVEL; EPIDERMIS; EXTRACTION; FLUORESCENCE; FOURIER TRANSFORMATION; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMAGE ANALYSIS; IN VITRO STUDY; NONHUMAN; OPTICAL DENSITY; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REFLECTOMETRY; REVIEW; SCINTILLATION; SKIN; SWINE; TECHNIQUE;

EID: 0032484044     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00060-1     Document Type: Article

References (51)

1. Touitou E., Abed L. Effect of propylene glycol, Azone and n-decylmethylsulphoxide on skin permeation kinetics of 5-fluorouracil. Int. J. Pharm. 27:1985;89-98.
2. Touitou E., Levi-Schaffer F., Dayan N., Alhaique F., Riccieri F. Modulation of caffeine skin delivery by carrier design: liposomes versus permeation enhancers. Int. J. Pharm. 103:1994;131-136.
3. Lafforgue C., Carret L., Falson F., Reverdy M.E., Freney J. Percutaneous absorption of a chlorhexidine digluconate solution. Int. J. Pharm. 147:1997;243-246.
4. Panchagnula R., Ritschell W.A. Development and evaluation of an intracutaneous depot formulation of corticosteroids using transcutol as a cosolvent: In vitro, ex vivo and in vivo rat studies. J. Pharm. Pharmacol. 43:1991;609-614.
5. Lehman P.A., Slattery J.T., Franz T.J. Percutaneous absorption of retinoids: Influence of vehicle light exposure, and dose. J. Invest. Dermatol. 91:1988;56-61.
6. Lehman P.A., Malany A.M. Evidence for percutaneous absorption of isotretinoin from the photo-isomerization of topical tretinoin. J. Invest. Dermatol. 93:1989;595-599.
7. Schaefer H., Stuttgen G., Zesch A., Schalla W., Gazith J. Quantitative determination of percutaneous absorption of radiolabelled drugs in vitro and in vivo by human skin. Curr. Probl. Dermatol. 7:1978;80-94.
8. Rougier A., Lotte C., Maibach H.I. In vivo percutaneous penetration of some organic compounds related to anatomic site in humans: predictive assessment by the stripping method. J. Pharm. Sci. 76:1987;451-454.
9. Meyer W., Schwarz R., Neurand K. The skin of domestic mammals as a model for the human skin, with special reference to the domestic pig. Curr. Probl. Dermatol. 7:1978;39-52.
10. 3H- labelled flupamesone. Drug Res. 25:1975;1040-1042.
11. Reifenrath W.G., Hawkins G.S., Kurtz M.S. Percutaneous penetration and skin retention of topically applied compounds: an in vitro-in vivo study. J. Pharm. Sci. 80:1991;526-532.
12. Monteiro-Riviere N.A., Inman A.O., Riviere J.E., McNeil S.C., Francoeur M.L. Topical penetration of piroxicam is dependent on the distribution of the local cutaneous vasculature. Pharm. Res. 10:1993;1326-1331.
13. Giese U. Absorption and distribution of ibuprofen from a cream formulation after dermal administration to guinea-pigs. Drug Res. 40:1990;84-88.
14. Rougier A., Dupius D., Lotte C., Roguet R., Schaefer H. In vivo correlation between stratum corneum reservoir function and percutaneous absorption. J. Invest. Dermatol. 81:1983;275-278.
15. Dupuis D., Rougier A., Roguet R., Lotte C., Kalopissis G. In vivo relationship between horny layer reservoir effect and percutaneous absorption in human and rat. J. Invest. Dermatol. 82:1984;353-356.
16. Rougier A., Dupius D., Lotte C., Roguet R. The measurement of the stratum corneum reservoir - a predictive method for in vivo percutaneous absorption studies: influence of application time. J. Invest. Dermatol. 84:1985;66-68.
17. Egbaria K., Ramachandran C., Weiner N. Topical delivery of ciclosporin: evaluation of various formulations using in vitro diffusion studies in hairless mouse skin. Skin Pharmacol. 3:1990;21-28.
18. Kammerau B., Zesch A., Schaefer H. Absolute concentrations of dithranol and triacetyl-dithranol in the skin layers after local treatment: in vivo investigations with four different types of pharmaceutical vehicles. J. Invest. Dermatol. 64:1975;145-149.
19. Schaefer H., Stuttgen G. Absolute concentrations of an antimycotic agent, econazole, in the human skin after local application. Drug Res. 26:1976;432-435.
20. Pellet M.A., Roberts M.S., Hadgraft J. Supersaturated solutions evaluated with an in vitro stratum corneum tape stripping technique. Int. J. Pharm. 151:1997;91-98.
21. Marks R., Dawber R.P.R. Skin surface biopsy: An improved method for the examination of the horny layer. Br. J. Dermatol. 84:1972;117-123.
22. Finlay A., Marks R. Determination of corticosteroid concentration profiles in the stratum corneum using the skin surface biopsy technique. Br. J. Dermatol. 107(Suppl. 22):1982;33.
23. Montenegro L., Ademola J.I., Bonina F.P., Maibach H.I. Effect of application time of betamethasone-17-valerate 0.1% cream on skin blanching and stratum corneum drug concentration. Int. J. Pharm. 140:1996;51-60.
24. Holyo-Tomoka M.T., Kligman A.M. Does cellophane tape stripping remove the horny layer? Arch. Dermatol. 106:1972;767-768.
25. van der Molen R.G., Spies F., van't Noordende J.M., Boelsma E., Mommaas A.M., Koerten H.K. Tape stripping of human stratum corneum yields cell layers that originate from various depths because of furrows in the skin. Arch. Dermatol. Res. 289:1997;514-518.
26. Marttin E., Neelissen-Subnel M.T.A., De Haan F.H.N., Bodde H.E. A critical comparison of methods to quantify stratum corneum removed by tape stripping. Skin Pharmacol. 9:1996;69-77.
27. Tsai J.C., Weiner N., Flynn G.L., Ferry J.J. Drug and vehicle deposition from topical applications: localization of minoxidil within skin strata of the hairless mouse. Skin Pharmacol. 7:1994;262-269.
28. U. Kiistala, The suction blister method for the in vivo separation of epidermis from dermis in human skin, Ph.D. Thesis, Helsinki, 1976.
29. Kligman A.M., Christophers E. Preparation of isolated sheets of human skin. Arch. Dermatol. 88:1963;702-705.
30. 14C]flutrimazole in mini-pigs. Drug Res. 42:1992;847-853.
31. W. Schalla, H. Schaefer, Localization of compounds in skin layers, in: Bronaugh R.L., Maibach H.I. (Editors), Percutaneous Absorption - Mechanism, Methodology - Drug Delivery, New York and Basel, 1985.
32. Lauer A.C., Flynn G.L., Weiner N.D. Transfollicular drug delivery. Pharm. Res. 12:1995;179-186.
33. Illel B., Saunal H., Muller D., Schaefer H. Skin surface biopsy methodology applied to penetration enhancing techniques: evaluation of skin penetration pathways. Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 21:1994;433-434.
34. Lieb L.M., Flynn G., Weiner N. Follicular (pilosebaceous unit) deposition and pharmacological behaviour of Cimetidine as a function of formulation. Pharm. Res. 11:1994;1419-1423.
35. Illel B., Schaefer H. Transfollicular percutaneous absorption: skin model for quantitative studies. Acta Derm. Venerol. 68:1988;427-430.
36. Heuber F., Wepierre J., Schaefer H. Role of transepidermal and transfollicular routes in percutaneous absorption of hydrocortisone and testosterone: in vivo study in the hairless rat. Skin Pharmacol. 5:1992;99-107.
37. Fabin B., Touitou E. Localization of lipophilic molecules penetrating rat skin in vivo by quantitative autoradiography. Int. J. Pharm. 74:1991;59-65.
38. B. Fabin, Skin Permeation of Tetrahydrocannabinol, Ph.D. Thesis (supervisor E. Touitou), Hebrew University, 1994.
39. E. Touitou, B. Fabin, A New Method for determination of Drugs in the Skin Region and Appendages, Image Computerized Quantitative Autoradiography, 6th Int. Conf. Pharm. Tech., 1992, pp. 296-302.
40. Touitou E., Alkabes M., Fabin B., Katz E., Horwitz E., Touitou D. Quantitative skin autoradiography: An efficient tool in measuring drug localized in skin layers, hair follicles and glands. Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 21:1994;431-432.
41. Klimich H.M., Chandra G. Use of Fourier transform infrared spectroscopy with alternate total reflectance for in vivo quantification of polydimethylsiloxanes on human skin. J. Soc. Cosmet. Chem. 37:1986;73-87.
42. Naik A., Pechtold L.A.R.M., Potts R.O., Guy R.H. Mechanism of oleic acid-induced skin penetration enhancement in vivo in humans. J. Contr. Rel. 37:1995;299-306.
43. Potts R.O., Guzek D.B., Harris P.R., McKie J.E. A non-invasive, in vivo technique to quantitatively measure water concentration in the stratum corneum using attenuated total reflectance infrared spectroscopy. Arch. Dermatol. Res. 277:1985;489-495.
44. Mak V.H.W., Potts R.O., Guy R.H. Percutaneous penetration enhancement in vivo measured by attenuated total reflectance infrared spectroscopy. Pharm. Res. 7:1990;835-841.
45. Pirot F., Kalia Y.N., Stinchcomb A.L., Keating G., Bunge A., Guy R.H. Characterization of the permeability barrier of human skin in vivo. Proc. Natl. Acad. Sci. 94:1997;1562-1567.
46. Feather J.W., Haijizadeh-Saffar M., Leslie G., Dawson J.B. A portable scanning reflectance spectrophotometer using visible wavelengths for the rapid measurement of skin pigmentation. Phys. Med. Biol. 34:1989;807-820.
47. Sennhenn B., Giese K., Plamann K., Harendt N., Kolmel K. In vivo evaluation of the penetration of topically applied drugs into human skin by spectroscopic methods. Skin Pharmacol. 6:1993;152-160.
48. Lieb L.M., Ramachandran C., Egbaria K., Weiner N. Topical delivery enhancement with multilamellar liposomes into pilosebaceous units: 1. In vitro evaluation using fluorescent techniques with the hamster ear model. J. Invest. Dermatol. 99:1992;108-113.
49. Jansen L.H., Hojyo-Tomodo M.T., Kligman A.M. Improved fluorescence staining for estimating turnover of the human stratum corneum. Br. J. Dermatol. 90:1974;9-12.
50. Kolmel K., Sennhen B., Giese K. Evaluation of drug penetration into the skin by photoacoustic measurement. J. Soc. Cosmet. 37:1986;375-385.
51. I. Simon, A.G. Emslie, C.M. Apt, I.M. Blank, R.R. Anderson, Determination of in vivo water concentration profile in human stratum corneum by a photoacoustic method, in: R. Marks, P.A. Payne (Editors), Bioengineering and the Skin, MTP Press, Lancaster, 1981, pp. 187-195.