The kinase activity of the antisigma factor SpoIIAB is required for activation as well as inhibition of transcription factor σ(F) during sporulation in Bacillus subtilis

Journal of Molecular Biology

Volumn 284, Issue 3, 1998, Pages 569-578

  Garsin, Danielle A ^a   Duncan, Leonard ^a,b   Paskowitz, Daniel M ^a,c   Losick, Richard ^a  

^a HARVARD UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antisigma factor; Bacillus subtilis; Phosphorylation; Protein protein interactions; Sporulation

Indexed keywords

ALANINE; PHOSPHOTRANSFERASE; SIGMA FACTOR; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BACILLUS SUBTILIS; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SPOROGENESIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS);

EID: 0032484027     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2202     Document Type: Article

References (27)

1. Alper, S., Duncan, L. & Losick, R. (1994). An adenosine nucleotide switch controlling the activity of a cell type- specific transcription factor in B. subtilis. Cell, 77, 195-205.
2. F during sporulation in Bacillus subtilis. Proc. Natl Acad. Sci. USA, 93, 3238-3242.
3. F is regulated by a binding protein (RsbW) that blocks its association with core RNA polymerase. Proc. Natl Acad. Sci. USA, 90, 2330-2334.
4. F of Bacillus subtilis. Genes Dev. 8, 2653-2663.
5. F from Bacillus subtilis. Proc. Natl Acad. Sci. USA, 90, 2325-2329.
6. Duncan, L., Alper, S., Arigoni, F., Losick, R. & Stragier, P. (1995). Activation of cell-specific transcription by a serine phosphatase at the site of asymmetric division. Science, 270, 641-644.
7. F from its anti-sigma factor SpoIIAB. J. Mol. Biol. 260, 147-164.
8. Feucht, A., Magnin, T., Yudkin, M. D. & Errington, J. (1996). Bifunctional protein required for asymmetric cell division and cell-specific transcription in Bacillus subtilis. Genes Dev. 10, 794-803.
9. F in Bacillus subtilis. J. Mol. Biol. 284, 557-568.
10. Harry, E. J., Pogliano, K. & Losick, R. (1995). Use of immunofluorescence to visualize cell-specific gene expression during sporulation in Bacillus subtilis. J. Bacteriol. 177, 3386-3393.
11. Harwood, C. R. & Cutting, S. M. (1990). Molecular Biological Methods for Bacillus, John Wiley & Sons, New York, NY.
12. Lewis, P. J., Partridge, S. R. & Errington, J. (1994). Sigma factors, asymmetry, and the determination of cell fate in Bacillus subtilis. Proc. Natl Acad. Sci. USA, 91, 3849-3853.
13. F of Bacillus subtilis. Gems Cell, 1, 881-894.
14. Magnin, T., Lord, M., Errington, J. & Yudkin, M. D. (1996). Establishing differential gene expression in sporulating Bacillus subtilis: phosphorylation of SpoIIAA (anti-anti-sigmaF) alters its conformation and prevents formation of a SpoIIAA/SpoIIAB/ ADP complex. Mol. Microbiol. 19, 901-907.
15. F activity in sporulating Bacillus sub-tilis. J. Bacteriol. 179, 3922-3927.
16. Margolis, P., Driks, A. & Losick, R. (1991). Establishment of cell type by compartmentalized activation of a transcription factor. Science, 254, 562-565.
17. F, the first compartment-specific transcription factor of B. subtilis, is regulated by an anti-sigma factor that is also a protein kinase. Cell, 74, 735-742.
18. F of Bacillus subtilis. J. Bacteriol. 177, 2912-2913.
19. Najafi, S. M., Harris, D. A. & Yudkin, M. D. (1997). Properties of the phosphorylation reaction catalyzed by SpoIIAB that help to regulate sporulation of Bacillus subtilis. J. Bacteriol. 179, 5628-5631.
20. Park, S. G. & Yudkin, M. D. (1997). Sequencing and phylogenetic analysis of the spoIIA operon from diverse Bacillus and Paenibacillus species. Gene, 194, 25-33.
21. F. Undergraduate thesis, Harvard University, Cambridge, MA.
22. Resnekov, O., Alper, S. & Losick, R. (1996). Subcellular localization of proteins governing the proteolytic activation of a developmental transcription factor in Bacillus subtilis. Genes Cells, 1, 529-542.
23. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. F by sporulation regulatory proteins SpoIIAA and SpoIIAB in Bacillus subtilis. Proc. Natl Acad. Sci. USA, 87, 9221-9225.
25. Stock, J. R., Surette, M. G., Levitt, M. & Park, P. (1995). Two-component signal transduction systems: structure-function relationships and mechanisms of catalysis. In Two-component Signal Transduction (Hoch, J. & Silhavy, T., eds), pp. 25-51, ASM Press, Washington, DC.
26. Stragier, P. & Losick, R. (1996). Molecular genetics of sporulation in Bacillus subtilis. Annu. Rev. Genet. 30, 297-241.
27. Yang, X., Kang, C. M., Brody, M. S. & Price, C. W. (1996). Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor. Genes Dev. 10, 2265-2275.