Amino acid substitutions in the C-terminal regulatory domain disrupt allosteric effector binding to biosynthetic threonine deaminase from Escherichia coli

Journal of Biological Chemistry

Volumn 273, Issue 36, 1998, Pages 23219-23224

  Chinchilla, Diana ^a   Schwarz, Frederick P ^b   Eisensteinen, Edward ^a,b,c  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^c UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERISM; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; EFFECTOR CELL; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; SIGMOID;

ALLOSTERIC REGULATION; AMINOBUTYRIC ACIDS; CALORIMETRY; CATALYSIS; ESCHERICHIA COLI; FEEDBACK; ISOLEUCINE; LIGANDS; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; THREONINE DEHYDRATASE; VALINE;

ANIMALIA; ESCHERICHIA COLI; SIGMOIDEA;

EID: 0032483527     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.36.23219     Document Type: Article

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