Modulation of baroreflex sensitivity by the state of protein tyrosine phosphorylation in the brainstem of the rat

Brain Research

Volumn 792, Issue 1, 1998, Pages 141-148

  Man, Heng Ye ^a   Erclik, Ted ^a   Becker, L E ^a   Wang, Yu Tian ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Anaesthetized rat; Baroreceptor; Blood pressure; Brainstem; Cardiovascular control; Tyrosine phosphorylation

Indexed keywords

GENISTEIN; INSULIN; PERVANADATE; PHENYLEPHRINE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BRAIN SLICE; BRAIN STEM; CARDIOVASCULAR AUTOREGULATION; CONTROLLED STUDY; HEART RATE; IMMUNOBLOTTING; MALE; MEDULLA OBLONGATA; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR SENSITIVITY; SIGNAL TRANSDUCTION;

ANIMALS; ATROPINE; BAROREFLEX; BRAIN STEM; ENZYME INHIBITORS; GENISTEIN; HEMODYNAMIC PROCESSES; MALE; MUSCARINIC ANTAGONISTS; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RATS, SPRAGUE-DAWLEY; VANADATES;

EID: 0032482128     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00199-1     Document Type: Article

References (20)

1. M.C. Andresen, D.L. Kunze, Nucleus tractus solitarius - gateway to neural circulatory control, Annu. Rev. Physiol. 56 (1994) 93-116.
2. S. Catarsi, P. Drapeau, Tyrosine kinase-dependent selection of trans-mitter responses induced by neuronal contact, Nature 363 (1993) 353-355.
3. C. Chen, J.P. Leonard, Protein tyrosine kinase-mediated potentiation of currents from cloned NMDA receptors, J. Neurosurg. 67 (1996) 194-200.
4. T. Erpel, S.A. Courtneidge, Src family protein tyrosine kinases and cellular signal transduction pathways, Curr. Opin. Cell Biol. 7 (1995) 176-182.
5. T.C. Holmes, D.A. Fadool, I.B. Levitan, Tyrosine phosphorylation of the Kv1.3 potassium channel, J. Neurosci. 16 (1996) 1581-1590.
6. T. Hunter, Protein modification: phosphorylation on tyrosine residues, Curr. Opin. Cell Biol. 1 (1989) 1168-1181.
7. J.B. Levy, P.D. Canoll, O. Silvennoinen, G. Barnea, B. Morse, A.M. Honegger, J.-T. Huang, L.A. Cannizzaro, S.-H. Park, T. Druck, K. Huebner, J. Sap, M. Ehrlich, J.M. Musacchio, J. Schlessinger, The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system, J. Biol. Chem. 268 (1993) 10573-10581.
8. O. Lindvall, Z. Kokaia, J. Bengzon, E. Elmer, M. Kokaia, Neurotrophins and brain insults, Trends Neurosci. 17 (1994) 490-496.
9. S.W. Mifflin, R.B. Felder, Synaptic mechanisms regulating cardiovascular afferent inputs to solitary tract nucleus, Am. J. Physiol. 259 (1990) H653-H661.
10. A receptors by tyrosine phosphorylation, Nature 377 (1995) 344-348.
11. T.J. O'Dell, E.R. Kandel, S.G. Grant, Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors, Nature 353 (1991) 558-560.
12. M.M. Sugrue, J.S. Brugge, D.R. Marshak, P. Greengard, E.L. Gustafson, Immunocytochemical localization of the neuron-specific form of the c-src gene product, pp60c-src(+), in rat brain, J. Neurosci. 10 (1990) 2513-2527.
13. A receptors, Mol. Brain Res. 31 (1995) 165-172.
14. K. Varga, N.S. Gantenberg, G. Kunos, Endogenous gamma-aminobutyric acid (GABA) mediates ethanol inhibition of vagally mediated reflex bradycardia elicited from aortic baroreceptors, J. Pharmacol. Exp. Ther. 268 (1994) 1057-1062.
15. K.R. Wagner, L. Mei, R.L. Huganir, Protein tyrosine kinases and phosphatases in the nervous system, Curr. Opin. Neurobiol. 1 (1991) 65-73.
16. A receptor function by tyrosine phosphorylation of β subunits, J. Neurosci. 17 (1997) 5062-5069.
17. A receptors to postsynaptic domains by insulin, Nature 388 (1997) 686-690.
18. Y.T. Wang, R.S. Neuman, D. Bieger, Nicotinic cholinoceptor-mediated excitation in ambigual motoneurones of the rat, Neurosci. 40 (1991) 759-767.
19. Y.T. Wang, M.W. Salter, Regulation of NMDA receptors by protein-tyrosine kinases and phosphatases, Nature 369 (1994) 233-235.
20. M. Wozniak, B. Rydzewski, S.P. Baker, M.K. Raizada, The cellular and physiological actions of insulin in the central nervous system, Neurochem. Int. 22 (1993) 1-10.