PMA alters folate receptor distribution in the plasma membrane and increases the rate of 5-methyltetrahydrofolate delivery in mature MA104 cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1401, Issue 2, 1998, Pages 157-169

  Lewis, Cheryl M ^a,b   Smith, Angela K ^b   Nguyen, Charles ^b   Kamen, Barton A ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Folate; Folate receptor; Phorbol 12 myristate 13 acetate; Potocytosis

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CELL SURFACE RECEPTOR; FOLIC ACID;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CELLULAR DISTRIBUTION; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; INTERNALIZATION; KIDNEY CELL; MONKEY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; SIGNAL TRANSDUCTION;

ANIMALS; CARCINOGENS; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; CYTOPLASM; ENDOCYTOSIS; FOLIC ACID; KINETICS; PROTEIN BINDING; PROTEIN KINASE C; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TETRADECANOYLPHORBOL ACETATE; TETRAHYDROFOLATES; TIME FACTORS; TRITIUM;

ANIMALIA;

EID: 0032481377     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(97)00126-2     Document Type: Article

References (46)

1. Quinn C.T., Kamen B.A. A biochemical perspective of methotrexate neurotoxicity with insight on nonfolate rescue modalities. J. Invest. Med. 44:1996;522-530.
2. Blount B.C., Mack M.M., Wehr C.M., MacGregor J.T., Hiatt R.A., Wang G., Wickramasinghe S.N., Everson R.B., Ames B.N. Folate deficiency causes misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage. Proc. Natl. Acad. Sci. U.S.A. 94:1997;3290-3295.
3. Fort D.W., Lark R.H., Smith A.K., Kamen B.A. Accumulation of 5-methyltetrahydrofolic acid and folylpolyglutamate synthetase expression by mitogen stimulated human lymphocytes. Brit. J. Haematol. 84:1993;595-601.
4. Dixon K.H., Lanpher B.C., Chiu J., Kelley K., Cowan K.H. A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. J. Biol. Chem. 269:1994;17-20.
5. Williams F.M.R., Murray R.C., Underhill T.M., Flintoff W.F. Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake. J. Biol. Chem. 269:1994;5810-5816.
6. Prasad P.D., Ramamoorthy S., Leibach F.H., Ganapathy V. Molecular cloning of the human placental folate transporter. Biochem. Biophys. Res. Commun. 206:1995;681-687.
7. Wong S.C., Proefke S.A., Bhushan A., Matherly L.H. Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese Hamster Ovary cells. J. Biol. Chem. 270:1995;17468-17475.
8. Moscow J.A., Gong M., He R., Sgagias M.K., Dixon K.H., Anzick S.L., Meltzer P.S., Cowan K.H. Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells. Cancer Res. 55:1995;3790-3794.
9. Wong S.C., McQuade R., Proefke S.A., Bhushan A., Matherly L.H. Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity. Biochem. Pharmacol. 53:1997;199-206.
10. S. Weitman, R.G.W. Anderson, B.A. Kamen, Folate binding proteins, in: K. Dakshinamurti (Ed.), Vitamin Receptors: Vitamins as Ligands in Cell Communites, Cambridge University Press, UK, 1994, pp. 106-136.
11. Anderson R.G.W., Kamen B.A., Rothberg K.G., Lacey S.W. Potocytosis: sequestration and transport of small molecules by caveolae. Science. 255:1992;410-411.
12. Smart E.J., Estes K., Anderson R.G.W. Inhibitors that block both the internalization of caveolae and the return of plasmalemmal vesicles. Cold Spring Harbor Symp. Quant. Biol. 60:1995;243-248.
13. Kamen B.A., Caston J.D. Properties of a folate binding protein (FBP) isolated from porcine kidney. Biochem. Pharmacol. 35:1986;2323-2329.
14. Kamen B.A., Wang M-T., Streckfuss A.J., Peryea X., Anderson R.G.W. Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J. Biol. Chem. 27:1988;13602-13609.
15. Kamen B.A., Smith A.K., Anderson R.G.W. The folate receptor works in tandem with a probenecid-sensitive carrier in MA104 cells in vitro. J. Clin. Invest. 87:1991;1442-1449.
16. Prasad P.D., Mahesh V.B., Leibach F.H., Ganapathy V. Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells. Biochem. Biophys. Acta. 1222:1994;309-314.
17. Kamen B.A., Capdevila A. Receptor-mediated folate accumulation is regulated by the cellular folate content. Proc. Natl. Acad. Sci. U.S.A. 83:1986;5983-5987.
18. Kamen B.A., Johnson C.A., Wang M-T., Anderson R.G.W. Regulation of the cytoplasmic accumulation of 5-methyltetrahydrofolate in MA104 cells is independent of folate receptor regulation. J. Clin. Invest. 84:1989;1379-1386.
19. Weitman S.D., Weinberg A.G., Coney L.R., Zurawski V.R., Jennings D.S., Kamen B.A. Cellular localization of the folate receptor: potential role in drug toxicity and folate homeostasis. Cancer Res. 52:1992;6708-6711.
20. Ross J.F., Chaudhuri P.K., Ratnam M. Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Cancer. 73:1994;2432-2443.
21. Willis S.A., Lacey S.W., Weitman S.D., Kamen B.A., Nisen P.D. Folate receptor gene expression is tissue-specific and temporally regulated. Cancer Therapy and Control. 2:1992;223-230.
22. Birn H., Nielsen S., Christensen E.I. Internalization and apical-to-basolateral transport of folate in rat kidney proximal tubule. Am. J. Physiol. 272:1997;F70-78.
23. Morshed K.M., McMartin K.E. Reabsorptive and secretory 5-methyltetrahydrofolate transport pathways in cultured human proximal tubule cells. Am. J. Physiol. 272:1997;F380-388.
24. Lark R.H., Smith A.K., Kamen B.A. Folate receptor expression, unlike folylpolyglutamate synthetase activity, is inversely related to MA104 cell proliferation in vitro. Cancer. Res. Ther. Control. 5:1996;1-10.
25. Smart E.J., Foster D.C., Ying Y-S., Kamen B.A., Anderson R.G.W. Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae. J. Cell Biol. 124:1994;307-313.
26. Zwiener R.J., Johnson C.A., Anderson R.G.W., Kamen B.A. Purified folate receptor 5-methyltetrahydrofolic acid interaction at neutral and acid pH. Cancer Res. Ther. Control. 3:1992;37-42.
27. B. Shane, Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism, in: Vitamins and Hormones, vol. 45, Academic Press, New York, 1989, pp. 263-335.
28. Henderson G.B., Zevely E.M. Inhibitory effects of probenecid on the individual transport routes which mediate the influx and efflux of methotrexate in L1210 cells. Biochem. Pharmacol. 34:1985;1725-1729.
29. Kazanietz M.G., Lewin N.E., Bruns J.D., Blumberg P.M. Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. J. Biol. Chem. 270:1995;10777-10783.
30. Gordge P.C., Ryves W.J. inhibitors of protein kinase C. Cellular Signalling. 6:1994;871-882.
31. Weitman S.D., Lark R.H., Coney L.R., Fort D.W., Frasca V., Zurawski V.R., Kamen B.A. Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues. Cancer Res. 52:1992;3396-3401.
32. Ahmed S., Kozma R., Monfries C., Hall C., Lim H.H.H., Smith P., Lim L. Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor. Biochem. J. 272:1990;767-773.
33. Maruyma I.N., Brenner S. A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 88:1991;5729-5733.
34. Omura S., Sasaki Y., Iwai Y., Takeshima H. Staurosporine, a potentially important gift from a microorganism. J. Antibiotics. 48:1995;535-548.
35. Davis P.D., Hill C.H., Keech E., Lawton G., Nixon J.S., Sedgwick A.D., Wadsworth J., Westmacott D., Wilkinson S.E. Potent selective inhibitors of protein kinase C. FEBS Lett. 259:1989;61-63.
36. Orr R.B., Kamen B.A. UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor. Cancer Res. 54:1994;3905-3911.
37. Orr R.B., Kreisler A.R., Kamen B.A. Similarity of folate receptor expression in UMSCC38 cells to squamous cell carcinoma differentiation markers. J. Natl. Cancer Inst. 87:1995;299-303.
38. Orr R.B., Kamen B.A. Identification of a point mutation in the folate receptor gene that confers a dominant negative phenotype. Cancer Res. 55:1995;847-852.
39. Pinard M.F., Jolivet J., Ratnam M., Kathman I., Molthoff C., Westerhof R., Schornagel J.H., Jansen G. Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate. Cancer Chemother. Pharmocol. 38:1996;281-288.
40. Brigle K.E., Spinella M.J., Westin E.H., Goldman I.D. Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells. Biochem. Pharmacol. 47:1994;337-345.
41. Parton R.G., Jogerst B., Simons K. Regulated internalization of caveolae. J. Cell Biol. 127:1994;1199-1215.
42. Sevinsky J.R., Vijay L., Rao M., Wolfram R. Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway. J. Cell Biol. 133:1996;293-304.
43. van den Bosch R.A., du Maine A.P.M., Geuze H.J., van der Ende A., Strous G.J. Recycling of 5′-nucleotidase in a rat hepatoma cell line. EMBO J. 7:1988;3345-3351.
44. S.-L. Shyng, M.T. Huber, D.A. Harris, A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells, J. Biol. Chem. (1993) 15922-15928.
45. Parolini I., Sargiacomo M., Lisanti M.P., Peschle C. Signal Transduction and glycophosphatidyl-linked proteins (LYN, LCK, CD4, CD45, G proteins, and CD) selectively localize in triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes. Blood. 87:1996;3783-3794.
46. Said H.M., Ma T.Y., Ortiz A., Tapia A., Valerio C.K. Intracellular regulation of intestinal folate uptake: studies with cultured IEC-6 epithelial cells. Am. J. Physiol. 272:1997;C729-C736.