Modified oligonucleotides with a 5'-5' interbase semi-rigid junction for alternate strand triplex formation

Tetrahedron Letters

Volumn 39, Issue 49, 1998, Pages 8991-8994

  Asseline, Ulysse ^a   Roig, Victoria ^a   Thuong, Nguyen T ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; OLIGONUCLEOTIDE; PHOSPHORAMIDIC ACID DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; MOLECULAR MODEL; NUCLEIC ACID STRUCTURE; TRIPLE HELIX;

EID: 0032481089     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02035-8     Document Type: Article

References (23)

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22. 3CN in 40 min. For compounds 7-9 three peaks were obtained (Rt = 10 min 15 sec, Rt = 17 min 43 sec and Rt = 35 min 51 sec). The first two were identified to dC and dT, respectively. The retention time of the last one was identical to that of the compound obtained after detritylation of 5. For the oligonucleotide 10 additional peaks were identified to 3′-amino-2′,3′-dideoxy-5-methyl-cytosine (Rt = 8 min 55 sec) and 3′-amino-2′,3′-dideoxythymidine (Rt = 11 min 16 sec).
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