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Volumn 8, Issue 5, 1998, Pages 405-408

Solid phase synthesis of a biased mini tetrapeptoid-library for the discovery of monodentate itam mimics as ZAP-70 inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; PHOSPHOTYROSINE; UNCLASSIFIED DRUG; ZAP 70 ANTAGONIST;

EID: 0032478162     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00043-2     Document Type: Article
Times cited : (17)

References (12)
  • 8
    • 0010547470 scopus 로고    scopus 로고
    • note
    • -4 M. Seven seconds into the dissociation phase, monitored for 2 min in free buffer flow, report points were taken to generate dose-response curves for estimating IC50 values; ie., the inhibitor concentrations causing a signal decrease of 50 percent. The sensorchip surfaces were very stable and could after sample injection be regenerated using 0.05 % (w/v) SDS.
  • 12
    • 0010581366 scopus 로고    scopus 로고
    • note
    • 3CN/TFA 50/50/0.05 within 15 min. at 60°C, 1 ml/min.) Under these conditions, 8 had a retention time of 9.2 min.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.