Sensitivity enhancement in transverse relaxation optimized NMR spectroscopy

Angewandte Chemie - International Edition

Volumn 37, Issue 20, 1998, Pages 2859-2861

  Zhu, Guang ^a   Kong, Xiangming ^a   Yan, Xianzhong ^a   Sze, Konghong ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

NMR spectroscopy; Proteins

Indexed keywords

ARTICLE; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0032476781     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19981102)37:20<2859::AID-ANIE2859>3.0.CO;2-4     Document Type: Article

References (20)

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20. 1H pulse needs to be considered. For optimal sensitivity, the phase of this pulse should be - y for Varian and +y for Bruker. If this phase is inverted then the "steady-state" enhancement, described by Pervushin et al. (J. Am. Chem. Soc. 1998, 720, 6394-6400) after this manuscript was submitted, will be lost. The sensitivity enhancement presented in this work is independent of the phase of this pulse and a √2 enhancement is gained over the corresponding TROSY experiment that has the same phase for this pulse.