Synthesis of optically active α-amino-phosphinic acids by catalytic asymmetric hydrogenation in organic solvents and aqueous micellar media

Angewandte Chemie - International Edition

Volumn 37, Issue 20, 1998, Pages 2851-2853

  Dwars, Torsten ^b   Schmidt, Ute ^b   Fischer, Christine ^b   Grassert, Ingrid ^b   Kempe, Rhett ^b   Fröhlich, Roland ^c   Drauz, Karlheinz ^a   Oehme, Günther ^b  

^a EVONIK INDUSTRIES AG   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Aminophosphinic acids; Asymmetric catalysis; Hydrogenations; Rhodium

Indexed keywords

1 N CARBOBENZOXY AMINO 2 PHENYLETHYLPHOSPHONOUS ACID; ALPHA AMINOCARBOXYLIC ACID; ALPHA AMINOPHOSPHINIC ACID; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ARTICLE; CHIRALITY; HYDROGENATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 0032476780     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19981102)37:20<2851::AID-ANIE2851>3.0.CO;2-F     Document Type: Article

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11. c value after subtraction.
12. 2
13. 2 (all data) = 0.096, 239 parameters, Flack parameter 0.01(3). Crystallographic data (excluding structure factors) for the structure reported in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC-101627. Copies of the data can be obtained free of charge on application to CCDC, 12 Union Road, Cambridge CB21EZ, UK (fax: (+44)1223-336033; e-mail: deposit@ccdc.cam. ac.uk).
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