Astrocytosis and amyloid deposition in scrapie-infected hamsters

Brain Research

Volumn 809, Issue 2, 1998, Pages 277-287

  Ye, Xuemin ^a   Scallet, Andrew C ^a   Kascsak, Richard J ^b   Carp, Richard I ^b  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Astrocyte; GFAP; Hamster; PrP; Scrapie

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; PRION PROTEIN;

ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; EPENDYMA CELL; HAMSTER; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOCYTOCHEMISTRY; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; SCRAPIE;

AMYLOIDOSIS; ANIMALS; ASTROCYTES; BRAIN; CRICETINAE; EPENDYMA; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; MESOCRICETUS; NERVE DEGENERATION; NEURITES; PRIONS; SCRAPIE;

EID: 0032476775     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00833-6     Document Type: Article

References (46)

1. Bendheim P.E., Potempska A., Kascsak R.J., Bolton D.C. Purification and partial characterization of the normal cellular homologue of the scrapie agent protein. J. Infect. Dis. 158:1988;1198-1208.
2. Bendheim P.E., Brown H.R., Rudelli R.D., Scala L.J., Goller N.L., Wen G.Y., Kascsak R.J., Cashman N.R., Bolton D.C. Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology. 42:1992;149-156.
3. Brown H.R., Goller N.L., Rudelli R.D., Merz G.S., Wolfe G.C., Wisniewski H.W., Robakis N.K. The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells. Acta Neuropathologica. 80:1990;1-6.
4. Bruce M.E., McBride P.A., Farquhar C.F. Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie. Neurosci. Lett. 102:1989;1-6.
5. Bruce M.E., McBride P.A., Jeffrey M., Scott J.R. PrP in pathology and pathogenesis in scrapie-infected mice. Molec. Neurobiol. 8(2-3):1994;105-112.
6. Carp R.I., Callahan S.M., Sersen E.A., Moretz R.C. Preclinical changes in weight of scrapie-infected mice as a function of scrapie agent-mouse strain combination. Intervirology. 21:1984;61-69.
7. Carp R.I., Kim Y.S., Callahan S.M. Pancreatic lesions and hypoglycemia-hyperinsulinemia in scrapie-injected hamsters. J. Infect. Dis. 161:1990;462-466.
8. R.I. Carp, R. Rubenstein, Diversity and significance of scrapie strains, in: A.T. Haase (Ed.), Seminars in Virology, Vol. 1, Academic Press, New York, 1991, pp. 203-213.
9. R.I. Carp, X. Ye, R.J. Kascsak, R. Rubenstein, The nature of the scrapie agent: biological characteristics of scrapie in different scrapie strain-host combinations, in: J. Bjornsson, R.I. Carp, A. Löve, H.W. Wisniewski (Eds.), Slow Infections of the Central Nervous System, Annals of New York Academy of Sciences, Vol. 724, New York, 1994, pp. 221-234.
10. Cashman N.R., Loertscher R., Nalbantoglu J., Shaw I., Kascsak R.J., Bolton D.C., Bendheim P.E. Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell. 61:1990;185-192.
11. DeArmond S.J., McKinley M.P., Barry R.A., Braunfeld M.B., McColloch J.R., Prusiner S.B. Identification of prion amyloid filaments in scrapie infected brain. Cell. 41:1985;221-235.
12. S.J. DeArmond, H.A. Kretzschmar, M.P. McKinley, S.B. Prusiner, Molecular pathology of prion disease, in: S.B. Prusiner, M.O. McKinley (Eds.), Prion, Novel Infectious Pathogens Causing Scrapie and Creutzfeldt-Jakob Disease, Academic Press, New York, 1987, pp. 387-414.
13. DeArmond S.J., Mobley W.C., DeMott D.L., Barry R.A., Beckstead J.H., Prusiner S.B. Changes in the localization of brain prion proteins during scrapie infection. Neurology. 37:1987;1271-1280.
14. Sc causes nerve cell death and stimulates astrocyte proliferation: a paradox, in: A.C.H. Yu, L. Hertz, M.D. Norenberg, E. Sykova, S.G. Waxman (Eds.), Progress in Brain Research, Vol. 94, Elsevier, Amsterdam, 1992, pp. 437-446.
15. A.G. Dickinson, M.E. Bruce, H. Fraser, R.H. Kimberlin, Scrapie strain differences; the implication of stability and mutation, in: J. Tateishi (Ed.), Proceedings of Workshop on Slow Transmissible Diseases, Japanese Ministry of health and Welfare, Tokyo, 1984, pp. 105-118.
16. Diedrich J.F., Minnigan H., Carp R.I., Whitaker J.N., Race R., Frey W., Haase A.T. Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J. Virol. 65:1991;4759-4768.
17. A.G. Dickinson, Scrapie in sheep and goats, in: R.H. Kimberlin (Ed.), Slow Virus Diseases in Animals and Man, North-Holland, Amsterdam, 1976, pp. 210-243.
18. Forloni G., Angeretti N., Chiesa R., Monzani E., Salmona M., Bugiani O., Tagliavini F. Neurotoxicity of a prion protein fragment. Nature. 362:1993;543-546.
19. Forloni G., Bo R.D., Angeretti N., Chiesa R., Smiroldo S., Doni R., Ghibaudi E., Salmona M., Porro M., Verga L., Giaccone G., Bugiani O., Tagliavini F. A neurotoxic prion protein fragment induces rat astroglial proliferation and hypertrophy. Eur. J. Neurosci. 6:1994;1415-1422.
20. Gomi H., Yokoyama T., Fujimoto K., Ikeda T., Katoh A., Itoh T., Itohara S. Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions. Neuron. 14:1995;29-41.
21. Hecker R., Taraboulos A., Scott M., Pan K.M., Yang S.L., Torchia M., Jendroska K., DeArmond S.J., Prusiner S.B. Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters. Gene. Devel. 6:1992;1213-1228.
22. Kascsak R.J., Fersko R., Pulgiano D., Rubenstein R., Carp R.I. Immunodiagnosis of prion disease. Lab. Invest. 26:1997;259-268.
23. Kimberlin R.H., Walker C.A. Characteristic of a short incubation model of scrapie in the golden hamster. J. Gen. Virol. 34:1977;295-304.
24. Kimberlin R.H., Walker C.A. Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly. J. Gen. Virol. 67:1986;255-263.
25. Kimberlin R.H., Walker C.A., Fraser H. The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice. J. Gen. Virol. 70:1989;2017-2025.
26. Kretzschmar H.A., Prusiner S.B., Stowring L.E., DeArmond S.J. Scrapie prion proteins are synthesized in neurons. Am. J. Pathol. 122:1986;1-5.
27. Li G., Bolton D.C. A novel hamster prion protein mRNA contains an extra exon: increased expression in scrapie. Brain Res. 751:1997;265-274.
28. Liberski P.P., Asher D.M., Yanagihara R., Gibbs G.J. Jr., Gajdusek D.C. Serial ultrastructural studies of scrapie in hamsters. J. Comp. Pathol. 101:1989;429-442.
29. Oesch B., Teplow D.B., Stahl N., Serban D., Hood L.E., Prusiner S.B. Identification of cellular proteins binding to the scrapie prion protein. Biochemistry. 29:1990;5848-5855.
30. Piccardo P., Safar J., Ceroni M., Gajdusek D.C., Gibbs C.J. Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue. Neurology. 40:1990;518-522.
31. Prusiner S.B. Novel proteinaceous infectious particles cause scrapie. Science. 216:1982;136-144.
32. Prusiner S.B., Scott M., Foster D., Pan K.M., Groth D.F., Mirenda C.A., Torchia M., Yang S.L., Serban D., Carlson G.A., Hoppe P.C., Westaway D., DeArmond S.J. Transgenic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell. 63:1990;673-686.
33. Safar J., Ceroni M., Piccardo P., Gajdusek D.C., Gibbs C.J. Scrapie-associated precursor proteins: antigenic relationship between species and immunohistochemical localization in normal, scrapie, and Creutzfeldt-Jakob disease brains. Neurology. 40:1990;513-517.
34. Schätzl H.M., Weiner R.J., Laszlo L., Holtzman D.M., Mobley W.C., Prusiner S.B. Apoptosis, vacuolation and infectivity in a novel cell line producing scrapie prions. Soc. Neurosci. Abstr. 18:1992;p1257.
35. D.C. Sheehan, B.B. Hrapchak (Eds.), Theory and Practice of Histotechnology, Battelle Press, Columbus, OH, 1980.
36. Williams A.E., Lawson L.K., Perry V.H., Fraser H. Characterization of the microglial response in murine scrapie. Neuropathol. Appl. Neurobiol. 20:1994;47-55.
37. Williams A.E., van Dam A.M., Man-A-Hing W.K.H., Berkenbosch F., Eikelenboom P., Fraser H. Cytokines, prostaglandins and lipocortin-1 are present in the brains of scrapie-infected mice. Brain Res. 654:1994;200-206.
38. Wisniewski H.M., Vorborodt A.W., Wegiel J., Morys J., Losinsky A.S. Ultrastructure of the cells forming amyloid fibers in Alzheimer disease and scrapie. Am. J. Med. Gen. Suppl. 7:1990;287-297.
39. X. Ye, R.I. Carp, R. Kascsak, R. Kozielski, P. Kozlowski, Astrocytosis and amyloid deposition in scrapie-infected hamsters, in: S. Fedoroff, B.H.J. Juurlink, R. Doucette (Eds.), Biology and Pathology of Astrocyte-Neuron Interactions, Plenum, New York, 1993, p. 443.
40. Ye X., Carp R.I., Yu Y., Kozielski R., Kozlowski P. Hyperplasia and hypertrophy of B-Cells in the islets of Langerhans in hamsters infected with the 139H strain of scrapie. J. Comp. Pathol. 110:1994;169-183.
41. Ye X., Carp R.I., Yu Y., Kozielski R., Kozlowski P. Histopathological changes in the islets of Langerhans in 139H-infected hamsters. J. Comp. Pathol. 110:1994;153-167.
42. Ye X., Carp R.I., Yu Y., Kozielski R., Kozlowski P. Effect of infection with the 139H scrapie strain on the number, area and/or location of hypothalamic CRF- and VP-immunostained neurons. Acta Neuropathologica. 88:1994;44-54.
43. Ye X., Carp R.I. The pathological changes in peripheral organs of scrapie-infected animals. Histol. Histopathol. 10:1995;995-1021.
44. Ye X., Carp R.I. Pathological changes in the pituitaries of female hamsters infected with the 139H strain of scrapie. J. Comp. Pathol. 114:1996;291-304.
45. Ye X., Scallet A., Carp R.I. The 139H scrapie agent produces hypothalamic neurotoxicity and pancreatic islet histopathology: electron microscopic studies. Neurotoxicology. 18(2):1997;533-545.
46. X. Ye, A. Scallet, R.J. Kascsak, R.I. Carp, Astrocytosis and proliferating cell nuclear antigen (PCNA) expression in brains of scrapie-infected hamsters, 1997, in preparation.