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Volumn 63, Issue 19, 1998, Pages PL267-PL274

Anticonvulsant phenytoinergic pharmacophores and anti-HIV activity - Preliminary evidence for the dual requirement of the 4-aminophthalimide platform and the N-(1-adamantyl) substitution for antiviral properties

(6) Vamecq, Joseph a Van Derpoorten, Kim b Poupaert, Jacques H b Balzarini, Jan c De Clercq, Erik c Stables, James P d

a INSERM (France)

b UNIVERSITÉ CATHOLIQUE DE LOUVAIN (Belgium)

c REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE (United States)

Author keywords

4 amino N (1 adamantyl)phthalimide; Adamantine; AIDS; Anti HIV drugs; Anticonvulsant drugs; Benzamide; Phenytoin; Phthalimide

Indexed keywords

4 AMINOBENZAMIDE; AMANTADINE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTICONVULSIVE AGENT; DRUG CARRIER; PHENYTOIN; PHTHALIMIDE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOSTASIS; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; ELECTRIC SHOCK; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; MOLECULAR MODEL; MOUSE; NONHUMAN; SEIZURE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 0032476159 PISSN: 00243205 EISSN: None Source Type: Journal
DOI: 10.1016/S0024-3205(98)00445-7 Document Type: Article

Times cited : (13)

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