-
1
-
-
13344259999
-
-
C. Dib et al., Nature 300, 152 (1996); J. C. Murray et al., Science 265, 2049 (1994).
-
(1996)
Nature
, vol.300
, pp. 152
-
-
Dib, C.1
-
2
-
-
0027942568
-
-
C. Dib et al., Nature 300, 152 (1996); J. C. Murray et al., Science 265, 2049 (1994).
-
(1994)
Science
, vol.265
, pp. 2049
-
-
Murray, J.C.1
-
3
-
-
0029653653
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
(1995)
Nature
, vol.377
, pp. 175
-
-
Chumakov, I.M.1
-
4
-
-
0029416826
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
(1995)
Science
, vol.270
, pp. 1945
-
-
Hudson, T.J.1
-
5
-
-
0026738541
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
(1992)
Nature
, vol.359
, pp. 380
-
-
Chumakov, M.1
-
6
-
-
0029653651
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
(1995)
Nature
, vol.377
, pp. 367
-
-
Collins, F.S.1
-
7
-
-
0029653653
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
Nature
, pp. 335
-
-
Doggett, N.A.1
-
8
-
-
0029653653
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
Nature
, pp. 321
-
-
Krauter, K.S.1
-
9
-
-
0029653653
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
Nature
, pp. 299
-
-
Gemmill, R.M.1
-
10
-
-
0030819029
-
-
For whole-genome physical maps, see I. M. Chumakov et al., Nature 377, 175 (1995); T. J. Hudson et al., Science 270, 1945 (1995). Detailed physical maps of some individual chromosomes (21, 22, 16, 12, 3, and 7) appear in the following: M. Chumakov et al., Nature 359, 380 (1992); F. S. Collins et al., ibid. 377, 367 (1995); N. A. Doggett et al., ibid., p. 335; K. S. Krauter et al., ibid., p. 321; R. M. Gemmill et al., ibid., p. 299; G. G. Bouffard et al., Genome Res. 7, 673 (1997).
-
(1997)
Genome Res.
, vol.7
, pp. 673
-
-
Bouffard, G.G.1
-
11
-
-
3543122432
-
-
in press (Oct. 23)
-
A transcript map of the human genome is available at http://ncbi.nlm.nih.gov/genemap. P. Deloukas et al., Science, in press (Oct. 23, 1998).
-
(1998)
Science
-
-
Deloukas, P.1
-
12
-
-
3543089842
-
-
A list of inherited disease genes identified by positional cloning is available at http://www.nhgri.nih.gov/ DIR/GTB/CLONE/.
-
-
-
-
14
-
-
0029653518
-
-
The genome sequence of H. influenzae was determined by whole-genome random sequencing and assembly [R. D. Fleischmann et al., Science 269, 496 (1995)].
-
(1995)
Science
, vol.269
, pp. 496
-
-
Fleischmann, R.D.1
-
15
-
-
0002641935
-
-
A. Goffeau et al., Nature 387 (suppl.), 1 (1997).
-
(1997)
Nature
, vol.387
, Issue.SUPPL.
, pp. 1
-
-
Goffeau, A.1
-
16
-
-
0029118499
-
-
A database cross-referencing human genes and related genes in model organisms is available at http://www.ncbi.nlm.nih.gov/XREFdb and also in D. Bassett et al., Trends Genet. 11, 372 (1996).
-
(1996)
Trends Genet.
, vol.11
, pp. 372
-
-
Bassett, D.1
-
17
-
-
0000465745
-
-
B. Birren, E. D. Green, S. Klapholz, R. M. Myers, J. Roskams, Eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
-
For methods, see E. Mardis and R. Wilson, in Genome Analysis, A Laboratory Manual, Vol. 1: Analyzing DNA, B. Birren, E. D. Green, S. Klapholz, R. M. Myers, J. Roskams, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1997), pp. 397-453; R. Wilson et al., Nature 368, 32 (1994).
-
(1997)
Genome Analysis, A Laboratory Manual, Vol. 1: Analyzing DNA
, vol.1
, pp. 397-453
-
-
Mardis, E.1
Wilson, R.2
-
18
-
-
0028295681
-
-
For methods, see E. Mardis and R. Wilson, in Genome Analysis, A Laboratory Manual, Vol. 1: Analyzing DNA, B. Birren, E. D. Green, S. Klapholz, R. M. Myers, J. Roskams, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1997), pp. 397-453; R. Wilson et al., Nature 368, 32 (1994).
-
(1994)
Nature
, vol.368
, pp. 32
-
-
Wilson, R.1
-
19
-
-
3543146073
-
-
These data are from the National Center for Biotechnology Information and Genome Monitoring Table at the European BioInformatic Institute. Currently, the largest sequence contig is over 2 Mb, and the largest mapped contig is 12.9 Mb (chromosome 22, available at http://webace.sanger.ac.uk/HGP/Chr22).
-
-
-
-
20
-
-
3543061752
-
-
Current and planned efforts of the international genome sequencing consortium are listed in the human genome sequence index (http://ncbi.nlm.nih.gov/HUGO). Graphic displays of the information can be viewed at http://webace.sanger.ac.uk or at http://www.ncbi.nlm.nih.gov/Entrez/Genome/org.html. D. Bentley et al., Trends Genet., in press.
-
-
-
-
21
-
-
3543072332
-
-
http://www.ncbi.nlm.nih.gov/Entrez/Genome/org.html. in press
-
Current and planned efforts of the international genome sequencing consortium are listed in the human genome sequence index (http://ncbi.nlm.nih.gov/HUGO). Graphic displays of the information can be viewed at http://webace.sanger.ac.uk or at http://www.ncbi.nlm.nih.gov/Entrez/Genome/org.html. D. Bentley et al., Trends Genet., in press.
-
Trends Genet.
-
-
Bentley, D.1
-
22
-
-
3543142491
-
-
note
-
Participants at the first international strategy meeting on human genome sequencing unanimously endorsed the "Bermuda statement" that "all human genomic information produced at large-scale sequncing centres should be freely available and in the public domain, in order to encourage research and development and to maximise its benefit to society." For details of access, see (8).
-
-
-
-
25
-
-
0032486191
-
-
J. C. Venter et al., Science 280, 1540 (1998).
-
(1998)
Science
, vol.280
, pp. 1540
-
-
Venter, J.C.1
-
29
-
-
3543055851
-
-
http://genetics.wustl.edu
-
Over 400 Mb of mapped clones for sequencing have been produced in our centers (see http://www.sanger.ac.uk or http://genetics.wustl.edu).
-
-
-
-
31
-
-
3543138956
-
-
note
-
We are grateful for discussions with F. Collins, M. Morgan, E. Lander, D. Cox, R. Gibbs, and M. Olson, who have expressed support. We also to thank the staff of the Sanger Centre and the Genome Sequencing Center for assistance in preparing the manuscript.
-
-
-
|