Fragment condensation on solid-phase in the synthesis of an amphiphilic glycopeptide from the homophilic recognition domain of epithelial cadherin 1

Tetrahedron Letters

Volumn 39, Issue 27, 1998, Pages 4797-4800

  Habermann, Jörg ^a   Kunz, Horst ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOPHILE; CADHERIN; GLYCOPEPTIDE;

ARTICLE; DRUG SYNTHESIS; POLYMERIZATION; REACTION ANALYSIS;

EID: 0032474706     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00923-X     Document Type: Article

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22. 12 Amino acid analyses were carried out by the Orpegen Pharma GmbH, Heidelberg (Germany) who supported this work with generous donations of amino acid derivatives.
23. T: 26.87 min (Eurospher 100-C8, 250×4, 1 ml/min, 1% MeCN (t = 0 min) - 100% MeCN (t = 42 min), 0.1% TFA).
24. 14 The yield is based on the amount of resin-linked starting amino acid.
25. 2 (see lit. 11b).
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29. T: 39.27 min (Vydac Protein C4, 250×4, 1 ml/min), 1% MeCN (t = 0 min) - 100% MeCN (t = 42 min), 0.1% TFA).
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32. T: 38.97 min (Vydac Protein C4, 250×4, 1 ml/min), 1% MeCN (t = 0 min) - 100% MeCN (t = 42 min), 0.1% TFA).