Synthesis of 1-deoxynojirimycin-trehalamine fused compound and its related compounds

Tetrahedron Letters

Volumn 39, Issue 14, 1998, Pages 1925-1928

  Shiozaki, Masao ^b   Ubukata, Osamu ^b   Haruyama, Hideyuki ^b   Yoshiike, Reiko ^a  

^a DAIICHI SANKYO CO   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYNOJIRIMYCIN DERIVATIVE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR;

ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; DRUG CONFORMATION; DRUG EFFECT; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0032473811     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00049-5     Document Type: Article

References (8)

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3. 3. O. Ando, M. Nakajima, K. Hamano, K. Itoi, S. Takahashi, Y. Takamatsu, A. Sato, R. Enokita, T. Okazaki, H. Haruyama, and T. Kinoshita, J. Antibiot., 46, 1116 (1993).
4. 4. Y. Kobayashi, H. Miyasaki, and M. Shiozaki, J. Org. Chem., 59, 813 (1994).
5. 1NMR analysis after the acetylation of the secondary alcohol of 2 by acetic anhydride-pyridine.
6. 6. H. S. Overkleeft, J. van Wiltenburg, and U. K. Pandit, Tetrahedron, 50, 4215 (1994).
7. 6a′H).
8. 2), 3.67 (1H, d, J=2.4 Hz), 3.73-3.77 (2H, m), 3.99 (1H, dd, J=2.4, 4.4 Hz), 4.16 (1H, d, J=8.3 Hz), 4.75 (1H, dd, J=1.0, 8.8 Hz).