Insulin bound to chiral polymer with N-acetyl-D-glucosaminyl units. Lack of mitogenic activity on rat aorta smooth muscle cell proliferation

Journal of Controlled Release

Volumn 50, Issue 1-3, 1998, Pages 197-203

  Chytry, Vladimir ^a   Letourneur, Didier ^b   Vrana, Antonin ^c   Jacqueline Jozefonvicz, ^a  

^a INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^b UNIVERSITÉ PARIS 13   (France)

^c INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Hypoglycemic activity; Insulin; N (2 hydroxypropyl)methacrylamide copolymers; N acetyl D glucosaminyl group; Smooth muscle cell proliferation

Indexed keywords

COPOLYMER; INSULIN DERIVATIVE; INSULIN RECEPTOR; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CELL PROLIFERATION; DRUG ACTIVITY; DRUG CONJUGATION; HYPOGLYCEMIA; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOISOMERISM;

ANIMALS; AORTA; CELL DIVISION; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MITOGENS; MUSCLE, SMOOTH, VASCULAR; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

EID: 0032472390     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00134-X     Document Type: Article

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