A simulation program for adaptive two stage designs

Computational Statistics and Data Analysis

Volumn 26, Issue 3, 1998, Pages 351-371

  Bauer, M ^a   Bauer, P ^a   Budde, M ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Adaptive designs; Dose finding; Fisher's combination test; Interim analysis; Power; Simulation program

Indexed keywords

COMPUTER SOFTWARE; DATA REDUCTION; PROBLEM SOLVING; STATISTICAL METHODS;

DOSE FINDING; FISCHER'S COMBINATION TEST; INTERIM ANALYSIS;

COMPUTER SIMULATION;

EID: 0032472153     PISSN: 01679473     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-9473(97)00034-0     Document Type: Article

References (20)

1. Agresti, A., 1990. Categorial Data Analysis. Wiley, New York, 1990, p. 241.
2. Armitage, P., 1955. Tests for linear trends in proportions and frequencies. Biometrics 11, 375-386.
3. Armitage, P.C., McPherson, B.C., Rowe, B.C., 1969. Repeated significance tests on accumulating data. J. Roy. Statist. Soc. Ser. A 132, 235-244.
4. Banik, N., Köhne, K., Bauer, P., 1996. On the power of Fisher's combination test for two stage sampling in the presence of nuisance parameters, Biomet. J. 38, 25-37.
5. Bauer, M., 1997. Simulation of adaptive two stage designs, Doctoral Thesis, Technical University of Vienna.
6. Bauer, P., 1989a. Multistage testing with adaptive designs. Biometrie Informatik Biologie Medizin 20 (4) 130-148.
7. Bauer, P., 1989b. Sequential tests of hypotheses in consecutive trials. Biomet. J. 31 (6) 663-676.
8. Bauer, P., Köhne, K., 1994. Evaluation of experiments with adaptive interim analyses. Biometrics 50, 1029-1041. Correction in Biometrics 52, 380.
9. Bauer, P., Köhne, K., 1994. Evaluation of experiments with adaptive interim analyses. Biometrics 50, 1029-1041. Correction in Biometrics 52, 380.
10. Bauer, P., Röhmel, J., 1995. An adaptive method of establishing a dose response relationship. Statist. Med. 14, 1595-1607.
11. Box, G.E.P., Muller, M.E., 1958. A note on generation of normal deviates. AMS 28, 610-611.
12. 2-test. Biometrics 10, 417-451.
13. Fisher, R.A., 1932. Statistical Methods for Research Workers, 4th ed. Oliver and Boyd, Edinburgh, pp. 99-101.
14. Hartung, J., 1982. Statistik. Lehr- und Handbuch der angewandten Statistik. R. Oldenbourg Verlag, München, Wien.
15. Hochberg, Y., Tamhane, A.J., 1987. Multiple Comparison Procedures. Wiley, New York, pp. 2-12.
16. Marcus, R., Peritz, E., Gabriel, K.R., 1976. On closed testing procedures with special reference to ordered analysis of variance. Biometrika 63, 655-660.
17. Pocock, S.J., 1977. Group sequential methods in the design and analysis of clinical trials. Biometrika 64, pp. 191-199.
18. SAS Institute Inc., 1990. SAS Language Reference Version 6-SAS Functions, pp. 521-616.
19. SAS Institute Inc., 1992. SAS Technical Report P-229, MULTTEST Procedure, pp. 37-404.
20. Stein, C., 1945. A two-sample test for a linear hypothesis whose power is independent of the Variance. Ann. Math. Statist. 16, 243-258.