Recombinant human growth hormone modulates Th1 and Th2 cytokine response in burned mice

Annals of Surgery

Volumn 228, Issue 1, 1998, Pages 106-111

  Takagi, Kazuya ^a   Suzuki, Fujiyo ^b   Barrow, Robert E ^a,b   Wolf, Steven E ^a,b   Herndon, David N ^a,b  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GROWTH HORMONE;

ANIMAL EXPERIMENT; ARTICLE; BURN; IMMUNE RESPONSE; IMMUNOREGULATION; INFECTION RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL;

ANIMALS; BURNS; CYTOKINES; GROWTH HORMONE; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0032470634     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000658-199807000-00016     Document Type: Article

References (39)

1. Kagan RJ, Naraqi S, Matsuda T, Jonasson OM. Herpes simplex virus and cytomegalovirus infection in burned patients. J Trauma 1985; 25:40-45.
2. Fader RC, Nunez D, Unbehagen J, Linares HA. Experimental candidiasis after thermal injury. Infect Immunol 1985; 49:780-784.
3. Pensler JM, Herndon DN, Ptak H, et al. Fungal sepsis: an increasing problem in major thermal injuries. J Burn Care Rehabil 1986; 7:488-491.
4. Hansbrough JF, Zapata-Sirvent BL, Peterson VM. Immunomodulation following bum injury. Surg Clin North Am 1987; 67:69-92.
5. Miller CL, Baker CC. Change in lymphocyte activity after thermal injury: the role of suppressor cells. J Clin Invest 1979; 63:202-210.
6. Suzuki F, Pollard RB. Alterations of interferon production in a mouse model of thermal injury. J Immunol 1982; 129:1806-1810.
7. Suzuki F, Pollard RB. Mechanism for the suppression of γ-interferon responsiveness in mice after thermal injury. J Immunol 1982; 129: 1811-1815.
8. Mosmann TR, Coffmann RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann Rev Immunol 1989; 7:145-173.
9. Salgame P, Abrams JS, Clayberger C, et al. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 1991; 254:279-282.
10. Sher A, Coffmann RL. Regulation of immunity to parasites by cells and T cell-derived cytokines. Ann Rev Immunol 1992; 10:385-409.
11. Scott P, Kaufmann SHE. The role of T-cell subsets and cytokines in the regulation of infection. Immunol Today 1991; 12:346-348.
12. Sher A, Gazzinelli RT, Oswald IP, et al. Role of T cell-derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev 1992; 127:183-204.
13. Mosmann TR. Cytokine patterns during the progression to AIDS. Science 1994; 265:193-194.
14. G. Interleukin-12 and its role in the generation of Th1 cells. Immunol Today 1993; 14:335-338.
15. Fitch FW, McKisic MD, Lancki DW, Gajewski TF. Differential regulation of murine lymphocyte subsets. Ann Rev Immunol 1993; 11: 29-43.
16. Kobayashi M, Herndon DN, Pollard RB, et al. CD4+ contrasuppressor T cells improve the resistance of thermally injured mice infected with HSV. J Leukoc Biol 1995; 58:159-167.
17. Gore DC, Honeycutt D, Jahoor F, et al. Effect of exogenous growth hormone on whole body and isolated limb protein kinetics in burned patients. Arch Surg 1991; 126:38-43.
18. Herndon DN, Hawkins HK, Nguyen TT, et al. Characterization of growth hormone-enhanced donor site healing in patients with large cutaneous burn. Ann Surg 1995; 221:649-659.
19. Edwards III CK, Ghiasuddin SM, Yunger LM, et al. In vivo administration of recombinant growth hormone or gamma interferon activates macrophages: enhanced resistance to experimental Salmonella typhimurium infection is correlated with generation of reactive oxygen intermediates. Infect Immunol 1992; 60:2514-2521.
20. Inoue T, Saito H, Fukushima R, et al. Growth hormone and insulin-like growth factor 1 enhance host defense in a murine sepsis model. Arch Surg 1995; 130:1115-1122.
21. Takagi K, Kaneko A, Barrow RE, et al. Recombinant human growth hormone protects thermally injured mice infected with herpes simplex virus. FASEB J 1996; 10:A1184.
22. Galdiero M, Donnarumma G, de l'Ero C, et al. Effect of growth hormone, prolactin and insulin on the release of IL-1, IFN-γ and IL-4 by staphylococcal enterotoxin A-stimulated splenocytes. Eur Cytokine Network 1995; 6:187-194.
23. Sommese L, Donnarumma G, de l'Ero C, et al. Growth hormone modulates IL-2 and IFN-γ release by murine splenocytes activated by LPS or porins of Salmonella typhimurium. J Med Microbiol 1996; 45:40-47.
24. Takagi K, Suzuki F, Barrow RE, et al. Growth hormone improves immune function and survival in burned mice infected with herpes simplex virus type 1. J Surg Res 1997; 69:166-170.
25. Baker FL, Galbraith PR. Mechanism of action of serum factors that regulate granulopoiesis in vitro: possible physiologic role of serum-inhibiting activity. Blood 1979; 53:304-312.
26. Morawetz RA, Doherty TM, Giese NA, et al. Resistance to murine acquired immunodeficiency syndrome (MAIDS). Science 1994; 265: 264-267.
27. Romagnani S, Prete GD, Manetti R, et al. Role of Th1/Th2 cytokines in HIV infection. Immunol Rev 1994; 140:73-92.
28. Matsuo R, Kobayashi M, Herndon DN, et al. Interleukin-12 protects thermally injured mice from herpes simplex virus type 1 infection. J Leukoc Biol 1996; 59:623-630.
29. O'Sullivan ST, Lederer JA, Horgan AF, et al. Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection. Ann Surg 1995; 222:482-492.
30. Noble A, Staynov DZ, Kemeny DM. Generation of rat Th2-like cells in vitro is interleukin-4 dependent and inhibited by interferon-γ. Immunology 1993; 79:562-567.
31. Sher A, Fiorentino DF, Casper P, et al. Production of IL-10 by CD4+ lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J Immunol 1991; 147:2713-2716.
32. Chatelain R, Varkila K, Coffmann RL. IL-4 induces a Th2 response in Leishmania major-infected mice. J Immunol 1992; 148:1182-1187.
33. 125I-human growth hormone to specific receptors in human cultured lymphocytes. J Biol Chem 1974; 249:1661-1667.
34. Gagnerault MC, Postel-Vinay MC, Dardenne M. Expression of growth hormone receptors in murine lymphoid cells analyzed by flow cytofluorometry. Endocrinology 1996; 137:1719-1726.
35. Hull KL, Thiagarajah A, Harvey S. Cellular localization of growth hormone receptors/binding proteins in immune tissues. Cell Tissue Res 1996; 286:69-80.
36. Yoshida A, Ishioka C, Kimata H, Mikawa H. Recombinant human growth hormone stimulates B cell immunoglobulin synthesis and proliferation in serum-free medium. Acta Endocrinol 1992; 126:524-529.
37. Schurmann A, Spencer GSG, Berry CJ. Growth hormone alters lymphocyte sub-populations and antibody production in dwarf rats in vivo. Experientia 1995; 51:780-785.
38. Leroith D, Yanowski J, Kaldjian EP, et al. The effects of growth hormone and insulin-like growth factor 1 on the immune system of aged female monkeys. Endocrinology 1996; 137: 1071-1079.
39. Rook G. Cell-mediated immune reactions. In: Roitt IM, Brostoff J, Male DK, eds. Immunology. London: Mosby; 1996:9.1-9.15.