Changes in the metabolism of lipoproteins in rats fed coconut kernel protein

Journal of Clinical Biochemistry and Nutrition

Volumn 25, Issue 3, 1998, Pages 159-168

  Nair, K Gopinathan Padmakumaran ^a   Rajamohan, Thankappan ^a   Kurup, Parameswara Achutha ^a,b  

^a UNIVERSITY OF KERALA   (India)

^b Peninsula Polymers Ltd   (India)

Author keywords

Hepatocytes; Kernel protein; Lipoprotein lipase; Lipoproteins; Plasma LCAT; Rats

Indexed keywords

EID: 0032469773     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.25.159     Document Type: Article

References (25)

1. Rajamohan, T., and Kurup, P.A. (1996): Study on the effect of consumption of coconut kernel and coconut oil on the serum lipid profile, in Project Report, Coconut Development Board, Ministry of Agriculture, Government of India.
2. Stamler, J., and Pick, R., and Katz, J.N. (1958): Effect of dietary proteins, methionine and vitamins on plasma lipids and atherogenesis in cholesterol fed cockerels. Circ. Res., 6, 442-446.
3. Sugiyama, K., Ohkawa, S., and Muramatsu, K. (1986): Relationship between amino acid composition of diet and plasma cholesterol levels in growing rats fed a high cholesterol diet J. Nutr. Sci. Vitaminol., 32, 413-423.
4. Sugano, M., Ishiwaki, N., Nagata, Y., and Imaizumi, K. (1982): Effects of arginine and lysine addition to casein and soybean protein on serum lipids, apolipoproteins, insulin and glucagon in rats. Br. J. Nutr., 48, 211-221.
5. Sugano, M., Yamada, Y., Yoshida, K., Hashimoto, Y., Matsuo, T., and Kimoto, M. (1988): The hypocholesterolemic action of the undigested fraction of soybean protein in rats. Atherosclerosis, 72, 115-122.
6. Huff, M.W., Hamilton, R.M.G., and Carroll, K.K. (1977): Plasma cholesterol levels in rabbits fed low fat, cholesterol free, semipurified diets. Effects of dietary proteins, protein hydrolysates and amino acid mixture. Atherosclerosis, 28, 187-195.
7. Kritchevsky, D., Tepper, S.A., Czarnecki, S.K., Klurfeid, D.M., and Story, J.A. (1981): Experimental atherosclerosis in rabbits fed cholesterol free diet. Part 9. Beef protein and textured vegetable protein. Atherosclerosis, 39, 169-175.
8. Hamilton, R.M.G., and Carroll, K.K. (1976): Plasma cholesterol levels in rabbits fed low fat, low cholesterol diets. Effect on dietary protein, carbohydrates and fiber from different sources. Atherosclerosis, 24, 47-62.
9. Carroll, K.K., Giovannetti, P.M., Huff, M.W., Moase, O., Robert, D.C.K., and Wolfe, B.M. (1978): Hypocholesterolemic effect of substituting soybean protein for animal protein in the diet of healthy young women. J. Nutr. Sci. Vitaminol., 32, 413-423.
10. Saraswathi Devi, K., and Kurup, P.A. (1972): Hypolipidemic activity of Phaseolus mango (Blackgram) in rats fed a high-fat-high cholesterol diet. Indian J. Exp. Biol., 15, 223-230.
11. Leelamma, S., Menon, P.V.G., and Kurup, P.A. (1978): Nature and quality of dietary protein and metabolism of lipids in rats fed normal and atherogenic diet. Indian J. Exp. Biol., 16, 36-42.
12. Sreedhara, N. (1988): Studies on oil palm (Elaeis guineensis) kernel protein as affected by processing condition, Ph.D. thesis, University of Mysore, India.
13. Rajamohan, T., and Kurup, P.A. (1977): Lysine : arginine ratio of a protein influences cholesterol metabolism. Part 1. Studies on sesame protein having low lysine : arginine ratio. Indian J. Exp. Biol., 35, 1218-1223.
14. Abraham, A., and Kurup, P.A. (1988): Mechanism of hypercholesterolemia produced by biotin deficiency. J. Biosci., 13, 393-399.
15. Schurr, P.E., Schultz, J.R., and Parkinson, T.M. (1972): Triton - induced hyperlipidemia in rats as an animal model for screening hypolipidemic drugs. Lipids, 7, 68-74.
16. Seglen, P.O. (1976): Preparation of isolated liver cells, in Methods in Cell Biology, Vol. 13, ed. by Prescott, D.M., Academic Press, New York, pp. 30-78.
17. Sureshkumar, N., Rita, A., Sureshkumar, G., Sudhakaran, P.R., and Kurup, P.A. (1992): Effect of fatty acids on the synthesis and secretion of apolipoprotein B by rat hepatocytes. J. Biosci., 17, 92-95.
18. Hatch, F.T., and Lees, R.S. (1968): Practical methods for plasma lipoprotein analysis, in Advances in Lipid Research, Vol. 6, ed. by Rodolfo, P., and David, K., Academic Press, London, pp. 2-68.
19. Sudhakaran, P.R., Stamatoglou, S.C., and Hughes, R.C. (1986): Modulation of protein synthesis and secretion by substratum in primary cultures of rat hepatocytes. Exp. Cell. Res., 167, 505-516.
20. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. (1951): Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
21. Snedecor, W.R., and Cochran, W.G. (1967): Statistical Methods, 6th Ed., The Iowa State, University Press, Ames, IA.
22. Sureshkumar, N., Rita, A., Sureshkumar, G., Sudhakaran, P.R., and Kurup, P.A. (1994): Synthesis and secretion of lipoproteins by primary cultures of rat hepatocytes. Indian J. Biochem. Biophys., 31, 62-67.
23. Padmakumaran Nair, K.G. (1997): Biochemical studies on coconut protein, Ph.D thesis, University of Kerala, India.
24. Rajamohan, T., and Kurup, P.A. (1986): Lysine : arginine ratio of protein and. its effect on cholesterol metabolism. Indian J. Biochem. Biophys., 23, 294-296.
25. Soma, M., Izumi, Y., Watanabe, Y., and Kanmatsue, K. (1996): A nitric oxide synthesis inhibitor decreased prostaglandin production in rat mesenteric vasculature. Prostaglandins, 51, 225-232.