Photobiological studies of new cyclopentene-psoralens

Farmaco

Volumn 53, Issue 10-11, 1998, Pages 638-644

  Dalla Via, Lisa ^a   Gia, Ornella ^a   Viola, Giampietro ^a   Bertoloni, Giulio ^a   Santana, Lourdes ^b   Uriarte, Eugenio ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Cyclopetene psoralens; Mutagenesis; Photobiological properties; Phototoxicity; Synthesis

Indexed keywords

CYCLOPENTANE DERIVATIVE; DNA; METHOXSALEN; PSORALEN;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA CROSS LINKING; DRUG ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; MUTAGENICITY; NONHUMAN; PHOTOTOXICITY; SKIN;

ADENOCARCINOMA; ANIMALS; CELL SURVIVAL; CYCLOPENTANES; DERMATITIS, PHOTOTOXIC; GUINEA PIGS; HELA CELLS; HUMANS; MUTAGENICITY TESTS; PHOTOBIOLOGY; PSORALENS; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032463077     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(98)00079-2     Document Type: Article

References (19)

1. J.A. Parrish, R.S. Stern, M.A. Pathak, T.B. Fitzpatrick, Photochemotherapy of skin diseases, in: J.D. Reagan, J.A. Parrish (Eds.), The Science of Photomedicine, Plenum, New York, 1982, pp. 595-624.
2. R. Edelson, C. Berger, F.P. Gasparro et al., Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. Preliminary results, N. Engl. J. Med. 316 (1987) 297-303.
3. C.R. Cantor, Photo-cross-linking studies of nucleic acid structure, Ann. N.Y. Acad. Sci. 346 (1980) 379-385.
4. F. Dall'Acqua, S. Caffieri, Recent and selected aspects of furocoumarin photochemistry and photobiology, Photomed. Photobiol. 10 (1988) 1-46.
5. D. Averbeck, Recent advances in psoralen phototoxicity mechanism, Photochem. Photobiol. 50 (1989) 859-882.
6. D. Averbeck, E. Moustacchi, Decreased photo-induced mutagenicity of mono-functional to bi-functional furocoumarins in yeast, Photochem. Photobiol. 31 (1980) 475-478.
7. M.A. Pathak, Mechanism in psoralen photosensitization reactions: photobiologic, toxicologic and pharmacologic aspects of psoralens, in: Monograph No. 66, M.A. Pathak, J.K. Dunnick, (Eds.), U.S. Department of Health and Human Services, Public Health Service, National Institute of Health, National Cancer Institute, Bethesda, 1984, pp. 41-46.
8. O. Gia, S. Mobilio, M. Palumbo, M.A. Pathak, Benzo- and tetrahydrobenzo-psoralen congeners: DNA binding and photobiological properties, Photochem. Photobiol. 57 (3) (1993) 497-503.
9. J. Blais, P. Vigny, J. Moron, E. Bisagni, Spectroscopic properties and photoreactivity with DNA of new monofunctional pyridopsoralens, Photochem. Photobiol. 39 (1984) 145-156.
10. M.J.S. Dewar, E.G. Zoebisch, E.F. Healy, J.J.P. Stewart, AMI: a new general purpose quantum mechanical molecular model, J. Am. Chem. Soc. 107 (1985) 3902-3909.
11. BIOSYM Technologies, 10065 Barnes Canyon Road, San Diego, CA 92121.
12. A. Wada, S. Kosawa, Instrument for the studies of differential flow dichroism of polymer solutions, J. Polym. Sci. 2 (1964) 853-864.
13. B. Norden, M. Kubista, T. Kurucsev, Linear dichroism spectroscopy of nucleic acids, Q. Rev. Biophys. 25 (1992) 51-170.
14. F. Carlassare, F. Baccichetti, A. Guiotto, P. Rodighiero, O. Gia, A. Capozzi, G. Pastorini, F. Bordin, Synthesis and photobiological properties of acetylpsoralen derivatives, J. Photochem. Photobiol. B: Biol. 5 (1990) 25-39.
15. D.M. Maron, B.N. Ames, Revised methods for the Salmonella mutagenicity test, Mutat. Res. 113 (1983) 173-215.
16. F. Tjerneld, B. Norden, B. Ljunggren, Interaction between DNA and 8-methoxypsoralen studied by linear dichroism, Photochem. Photobiol. 29 (1979) 1115-1118.
17. P. Vigny, J. Blais, V. Ibanez, Flow linear dichroism study of the orientation of 4′-5′-psoralen-DNA photoadducts, Photochem. Photobiol. 45 (1987) 601-607.
18. E. Sage, Molecular basis of UV and psoralen mutagenesis, J. Photochem. Photobiol. B: Biol. 20 (1993) 211-217.
19. M. Collet, J. Piette, Analysis of mutations induced by 4′-hydroxymethyl-4,5′,8-trimethylpsoralen and UVA in Escherichia coli lac Z gene and its regulatory region, J. Photochem. Photobiol. B: Biol. 20 (1993) 145-152.