A change-in-hand mechanism for S100 signalling

Biochemistry and Cell Biology

Volumn 76, Issue 2-3, 1998, Pages 324-333

  Smith, Steven P ^a   Shaw, Gary S ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Calcium binding protein; Conformational change; EF hand; S100

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; PROTEIN S 100;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BINDING AFFINITY; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 21; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

EID: 0032462776     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o98-062     Document Type: Review

References (69)

1. Allore, R., O'Hanlon, D., Price, R., Neilson, K., Willard, H.F., Cox, D.R., Marks, A., and Dunn, R.J. 1988. Gene encoding the subunit of S-100 protein is on chromosome 21: implications for Down Syndrome. Science (Washington, D.C.), 239: 1311-1313.
2. 15N NMR assignments and solution secondary structure of rat Apo-S100β. J. Biomol. NMR, 6: 171-179.
3. 2+ stimulates disulfide cross-linking between the S100b β-subunit and the microtubule-associated τ(2) protein. J. Biol. Chem. 263: 5876-5883.
4. 2+-binding sequence in bovine brain S100b protein β-subunit. Biochem. J. 264: 79-85.
5. Baudier, J., and Gerard, D. 1986. Ions binding to s100 proteins. II. Conformational studies and calcium-induced conformational changes in s100αα protein: the effect of acidic pH and calcium incubation on subunit exchange in s100a (αβ) protein. J. Biol. Chem. 261: 8402-8212.
6. 2+ binding to S100b protein. J. Biol. Chem. 261: 8192-8203.
7. Baudier, J., Mochly-Rosen, D., Newton, A., Lee, S.-H., Koshland, D.E., and Cole, R.D. 1987. Comparison of S100b with calmodulin: interactions of melittin and microtubule-associated proteins and inhibition of phosphorylation of τ proteins by protein kinase C. Biochemistry, 26: 2886-2893.
8. Baudier, J., Delphin, C., Grunwald, D., Khochbin, S., and Lawrence, J.J. 1992. Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein. Proc. Natl. Acad. Sci. U.S.A. 89: 11 627-11 631.
9. 2+-dependent manner. J. Biol. Chem. 268: 12 669-12 674.
10. Dell'Angelica, E.C., Schleicher, C.H., and Santome, J.A. 1994. Primary structure and binding properties of calgranulin C, a novel S100-like calcium-binding protein from pig granulocytes. J. Biol. Chem. 269: 28 929-28 936.
11. Donaldson, C., Barber, K.A., Kay, C.M., and Shaw, G.S. 1995. Human S100b protein: Formation of a tetramer from synthetic calcium-binding peptides. Protein Sci. 4: 765-772.
12. Donato R. 1988. Calcium-independent, pH-regulated effects of S-100 proteins on assembly-disassembly of brain microtubule protein in vitro. J. Biol. Chem. 263: 106-110.
13. Donato, R. 1991. Perspectives in S-100 biology. Cell Calcium, 12: 713-726.
14. Donato, R., Giambanco, I., and Aisa, M.C. 1989. Molecular interaction of S-100 proteins with microtubule proteins in vitro. J. Neurochem. 53: 566-571.
15. Drohat, A.C., Amburgey, J.C., Abildgaard, F., Starich, M.R., Baldisseri, D., and Weber, D.J. 1996. Solution structure of rat apo-S100B(ββ) as determined by NMR spectroscopy. Biochemistry, 35: 11 577-11 588.
16. Drohat, A.C., Baldisseri, D.M., Rustandi, R.R., and Weber, D.J. 1998. Solution structure of calcium-bound rat S100B(ββ) as determined by NMR spectroscopy. Biochemistry, 37: 2729-2740.
17. Fanò, G., Biocca, S., Fulle, S., Mariggio, M., Belia, S., and Calissano, P. 1995. The S-100: a protein family in search of a function. Prog. Neurobiol. (Oxford), 46: 71-82.
18. Gagné, S.M., Tsuda, S., Li, M.X., Chandra, M., Smillie, L.B., and Sykes, B.D. 1994. Quantification of the calcium-induced secondary structural changes in the regulatory domain of troponin-C. Protein Sci. 3: 1961-1974.
19. Gagné, S.M., Tsuda, S., Li, M.X., Smillie, L.B., and Sykes, B.D. 1995. Structures of the troponin C regulatory domains in the apo and calcium-saturated states. Nat. Struct. Biol. 2: 784-789.
20. Griffin, W.S.T., Stanley, L.C., Ling, C., White, L., MacLeod, V., Perrot, L.J., White, C.L., and Araoz, C. 1989. Brain interleukin 1 and S100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 86: 7611-7615.
21. 1H nuclear magnetic resonance studies. Protein Sci. 6: 323-330.
22. Groves, P., Finn, B.E., Kuznicki, J., and Forsén, S. 1998. A model for target protein binding to calcium-activated S100 dimers. FEBS Lett. 421: 175-179.
23. 2+/S100 regulation of giant protein kinases. Nature (London), 380: 636-639.
24. Ikura, M. 1996. Calcium binding and conformational response in EF-hand proteins. Trends Biochem. Sci. 21: 14-17.
25. 15N spectra of larger proteins. Heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin. Biochemistry, 29: 4659-4667.
26. Ikura, M., Clore, G.M., Gronenborn, A.M., Zhu, G., Klee, C.B., and Bax, A. 1992. Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science (Washington, D.C.), 256: 632-638.
27. Ivanenkov, V.V., Jamieson, G.A., Gruenstein, E., and Dimlich, R.V.W. 1995. Characterization of S-100b binding epitopes: identification of a novel target, the actin capping protein CapZ. J. Biol. Chem. 270: 14 651-14 658.
28. Kilby, P.M., Van Eldik, L.J., and Roberts, G.C.K. 1995. Nuclear magnetic resonance assignments and secondary structure of bovine S100β protein. FEBS Lett. 363: 90-96.
29. Kilby, P.M., Van Eldik, L.J., and Roberts, G.C.K. 1996. The solution structure of the bovine S100B protein dimer in the calcium-free state. Structure (London), 4: 1041-1052.
30. Kilby, P.M., Van Eldik, L.J., and Roberts, G.C.K. 1997. Identification of the binding site on S100B protein for the actin capping protein CapZ. Protein Sci. 6: 2494-2503.
31. Kligman, D., and Hilt, D.C. 1988. The S100 protein family. Trends Biochem. Sci. 13: 437-443.
32. 9k. J. Mol. Biol. 231: 711-734.
33. Kraulis, P.J. 1991. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24: 946-950.
34. Kretsinger, R.H., Rudnick, S.E., Snedan, D.A., and Schatz, V.B. 1980. Calmodulin, S100, and crayfish sarcoplasmic calcium-binding protein crystals suitable for x-ray diffraction studies. J. Biol. Chem. 255: 8154-8156.
35. Krudy, G.A., Brito, R.M.M., Putkey, J.A., and Rosevear, P.R. 1992. Conformational changes in the metal-binding sites of cardiac troponin C induced by calcium binding. Biochemistry, 31: 1595-1602.
36. 2+ binding sites and interactions with troponin I and troponin T. J. Biol. Chem. 253: 5452-5459.
37. 9k. Biochemistry, 26: 6723-6735.
38. 9k: stability, calcium binding and NMR studies. Protein Sci. 2: 985-1000.
39. Mani, R.S., Shelling, J.G., Sykes, B.D., and Kay, C.M. 1983. Spectral studies on the calcium binding properties of bovine brain s-100b protein. Biochemistry, 22: 1734-1740.
40. Manning, M.C. 1989. Underlying assumptions in the estimation of secondary structure content in proteins by circular dichroism spectroscopy: a critical review. J. Pharm. Biomed. Anal. 7: 1103-1119.
41. Marsden, B.J., Shaw, G.S., and Sykes, B.D. 1989. Calcium binding proteins. Elucidating the contributions to calcium affinity from analysis of species variants and peptide fragments. Biochem. Cell Biol. 68: 587-601.
42. Marshak, D.R., Pesce, S.A., Stanley, L.C., and Griffin, W.S.T. 1991. Increased S100b neurotrophic activity in Alzheimer's disease temporal lobe. Neurobiol. Aging, 13: 1-7.
43. 2+ on the secondary and tertiary structure of bovine testis calmodulin. Biochem. J. 238: 485-490.
44. Matsumura, H., Shiba, T., Inoue, T., Harada, S., and Kai, Y. 1998. A novel mode of target recognition suggested by the 2.0 Å structure of holo S100B from bovine brain. Structure (London), 6: 233-241.
45. Moore, B.W. 1965. A soluble protein characteristic of the nervous system. Biochem. Biophys. Res. Commun. 19: 739-744.
46. Moore, B.W. 1988. The S100 protein. In Neuronal and glial proteins: structure, function and clinical application. Academic Press, New York. pp. 137-167.
47. 39K N.M.R. Int. J. Biol. Macromol. 14: 279-286.
48. 2+-binding proteins. Nat. Struct. Biol. 2: 790-796.
49. 9k and S100β Protein Sci. 5: 1-13.
50. 2+-dependent interaction of S100B (ββ) with a peptide derived from p53. Biochemistry, 37: 1951-1960.
51. 2+-signal transduction by S100 proteins. Structure (London), 6: 223-231.
52. Satyshur, K.A., Rao, S.T., Pyzalska, D., Drendel, W., Greaser, M., and Sundaralingam, M. 1988. Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-Å resolution. J. Biol. Chem. 263: 1628-1647.
53. Schäfer, B.W., and Heizmann, C.W. 1996. The S100 family of EF-hand calcium-binding proteins: functions and pathology. Trends Biochem. Sci. 21: 134-140.
54. Schäfer, B.W., Wicki, R., Englekamp, D., Mattei, M.G., and Heizmann, C.W. 1995. Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. Genomics, 25: 638-643.
55. 9k. Biochemistry, 29: 5752-5761.
56. 9k by NMR spectroscopy. J. Mol. Biol. 249: 441-462.
57. Slupsky, C.M., Kay, C.M., Reinach, F.C., Smillie, L.B., and Sykes, B.D. 1995a. Calcium-induced dimerization of troponin C: mode of interaction and use of trifluoroethanol as a denaturant of quaternary structure. Biochemistry, 34: 7365-7375.
58. Slupsky, C.M., Reinach, F.C., Smillie, L.B., and Sykes, B.D. 1995b. Solution secondary structure of calcium-saturated troponin C monomer determined by multidimensional heteronuclear NMR spectroscopy. Protein Sci. 4: 1279-1290.
59. Smith, S.P., and Shaw, G.S. 1997. Assignment and secondary structure of calcium-bound human S100B. J. Biomol. NMR, 10: 77-88.
60. Smith, S.P., and Shaw, G.S. 1998. A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form. Structure (London), 6: 211-222.
61. Smith, S.P., Barber, K.R., Dunn, S.D., and Shaw, G.S. 1996. Structural influence of cation binding to recombinant human brain S100b: evidence for calcium-induced exposure of a hydrophobic surface. Biochemistry, 35: 8805-8814.
62. Smith, S.P., Barber, K.R., and Shaw, G.S. 1997. Identification and structural influence of a differentially modified N-terminal methionine in human S100b. Protein Sci. 6: 1110-1113.
63. Strynadka, N.C.J., and James, M.N.G. 1989. Crystal structures of the helix-loop-helix calcium-binding proteins. Annu. Rev. Biochem. 58: 951-998.
64. Szebenyi, D.M.E., and Moffat, K.J. 1986. The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. J. Biol. Chem. 261: 8761-8777.
65. 2+/phopholipid binding proteins, annexin family. J. Biol. Chem. 267: 8919-8924.
66. Van Eldik, L.J., and Griffin, W.S.T. 1994. S100b expression in Alzheimer's disease: relation to neuropathology in brain regions. Biochim. Biophys. Acta, 1223: 398-403.
67. 13C chemical-shift data. J. Biomol. NMR, 4: 171-180.
68. Wishart, D.S., Sykes, B.D., and Richards, F.M. 1992. The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy. Biochemistry, 31: 1647-1651.
69. Zimmer, D.B., Cornwall, E.H., Landar, A., and Song, W. 1995. The S100 protein family: history, function, and expression. Brain Res. Bull. 37: 417-429.