Mutagenicity and dark toxicity of the second-generation photosensitizer bacteriochlorin a

Journal of Photochemistry and Photobiology B: Biology

Volumn 47, Issue 2-3, 1998, Pages 211-215

  Schuitmaker, J J ^a   Vogel, E W ^a   Nagelkerke, J F ^b   Bos, R P ^c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Bacteriochlorin; Mutagenicity; Photodynamic therapy; Sensitizers; Toxicity

Indexed keywords

BACTERIOCHLORIN; LACTATE DEHYDROGENASE; MELANIN; PHOTOSENSITIZING AGENT;

ABSORPTION; ANIMAL CELL; ARTICLE; BIOASSAY; CELL DEATH; CONTROLLED STUDY; CYTOSOL; DROSOPHILA MELANOGASTER; EUKARYOTIC CELL; GENOTOXICITY; HETEROZYGOSITY LOSS; ILLUMINATION; IN VITRO STUDY; IN VIVO STUDY; LARVA; LIVER CELL; MITOSIS; MOSAICISM; MUTAGENICITY; NONHUMAN; PHOTOSENSITIVITY; PRIORITY JOURNAL; PROKARYOSIS; RAT; RECOMBINANT DNA TECHNOLOGY; REVERTANT; SALMONELLA TYPHIMURIUM; SKIN; SOMATIC CELL; SOMATIC MUTATION; TISSUE; TOXICITY; TUMOR MODEL;

ANIMALS; CELLS, CULTURED; DARKNESS; DROSOPHILA MELANOGASTER; LIVER; PHOTOSENSITIZING AGENTS; PORPHYRINS; RATS; SALMONELLA TYPHIMURIUM;

EID: 0032459045     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1011-1344(99)00005-6     Document Type: Article

References (19)

1. [1] E.M. Beems, T.M.A.R. Dubbelman, J. Lugtenburg, J.A. van Best, M.F.M.A. Smeets, J.P.J. Boegheim, Photosensitizing properties of bacteriochlorophylliti a and bacteriochlorin a, two derivatives of bacteriochlorophyll a, Photochem. Photobiol. 46 (5) (1987) 639-643.
2. [2] J.J. Schuitmaker, J.A. van Best, J.L. van Delft, T.M.A.R. Dubbelman, J.A. Oosterhuis, D. de Wolff-Rouendaal, Bacteriochlorin a, a new photosensitizer in photodynamic therapy. In vivo results, Invest. Ophthalmol. Vis. Sci. 31 (1990) 1444-1450.
3. [3] H.L. Van Leengoed, J.J. Schuitmaker, N. van der Veen, T.M.A.R. Dubbelman, W.M. Star, Fluorescence and photodynamic effects of bucteriochlorin a observed in vivo in 'sandwich' observation chambers, Br. J. Cancer 67 (1993) 898-903.
4. [4] I.P. Van Geel, H. Oppelaar, Y.G. Oussoren, J.J. Schuitmaker, F.A. Stewart, Mechanisms for optimizing photodynamic therapy: second-generation photosensitizes in combination with mitomycin C, Br. J. Cancer 72 (1995) 344-350.
5. [5] M. Hoebeke, H.J. Schuitmaker, L.E. Jannink, T.M.A.R. Dubbelman, A. Jacobs, A. van de Vorst, Electron spin resonance evidence of the generation of superoxide anion hydroxyl radical and singlet oxygen during the photohemolysis of human ery throcytes with bacteriochlorin a, Photochem. Photobiol. 66 (4) (1997) 502-508.
6. [6] B. Epe, Genotoxicity of singlet oxygen. Review article, Chem. Biol. Interactions 80 (1991) 239-260.
7. [7] L. C Penning, J.W.M. Lagerberg, J.H. Van Dierendonck, C.J. Cornelisse, T.M.A.R. Dubbelman, J. van Stevenmck, The role of DNA damage and inhibition of poly(ADP-ribosyl) ation in loss of clonogenicity of murine L929 fibroblasts, caused by photodynamically induced oxidative stress, Cancer Res. 54 (21) (1994) 5561-5567.
8. [8] D.M. Maron, B.N. Ames, Revised methods for the Salmonella mutagenicity test, Mutation Res. 113 (1983) 173-215.
9. 99mTc-pertechnetate in hamster Greene melanoma, Int. J. Radiat. Biol. 64 (4) (1993) 451-158.
10. [10] E.W. Vogel, Test for recombinagens in somatic cells of Drosophila, Mutation Res. 284 (1992) 159-175.
11. [11] D. Lasko, W. Cavenee, Loss of constitutional heterozygosity in human cancer, Annu. Rev. Genet. 25 (1991) 281-314.
12. [12] G. Oster, B. Broyde, J.S. Bellin, Spectral properties of chlorophyllin a, J. Am. Chem. Soc. 5 (1964) 1309-1313.
13. [13] P.P. Seglen, Preparation of isolated rat liver cells, Methods Cell Biol. 13 (1976) 29-83.
14. [14] E.W. Vogel, M.J.M. Nivard, Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination, Mutagenesis 8 (1993) 57-81.
15. [15] H. Frei, F.E. Würgler, Statistical methods to decide whether mutagenicity test data from Drosophila indicate a positive, negative or inconclusive result, Mutation Res. 203 (1988) 297-308.
16. [16] D. Averbeck, K. Polasa, J. Buisson, R. Bensasson, M. Rougée, J. Cadet, J. Ravanat, F. Perin, P. Vigny, P. Demerseman, Photobiological activities of 1,6-dioxapyrene in pro-and eukaryotic cells, Mutation Res. 287 (1993) 165-179.
17. [17] L. Romert, M. Curvall, D. Jenssen, Chlorophyllin is both a positive and negative modifier of mutagenicity, Mutagenesis 7 (1992) 349-355.
18. [18] J.J. Schuitmaker, G.F.J.M. Vrensen, J.L. van Delft, D. de Wolff-Rouendaal, T.M.A.R. Dubbelman, A. de Wolf, Morphologic effects of bacteriochlorin a and light in vivo on intraocular melanoma, Invest. Ophthalmol. Vis. Sci. 32 (10) (1991) 2683-2688.
19. [19] J.J. Schuitmaker, J.E. Jannink, J.F. Nagelkerke, G.F.J.M. Vrensen, Intracellular localization and light-induced rel realization of bacteriochlorin a in vitro studied by confocal laser scanning and electron microscopy, Proc. 6th Biennial Meet. Int. Photodynamic Association, Melbourne, Australia, 1996, A 130.