Appearance and maturation of T-Cell subsets during rat thymus ontogeny

Developmental Immunology

Volumn 5, Issue 4, 1998, Pages 319-331

  Vicente, A ^a   Varas, A ^a   Acedon R S ^a   Jimenez E ^a   Munoz J J ^a   Zapata, A G ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Ontogeny; Rat thymus; T cell development

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR; LEUKOSIALIN; T LYMPHOCYTE RECEPTOR; THY 1 ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; DENDRITIC CELL; DEVELOPMENT; EPITHELIUM CELL; FETUS; MACROPHAGE; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROLYMPHOCYTE; RAT; T LYMPHOCYTE SUBPOPULATION; THYMUS;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0032458143     PISSN: 10446672     EISSN: None     Source Type: Journal    
DOI: 10.1155/1998/24239     Document Type: Article

References (44)

1. Adkins B. (1991). Developmental regulation of the intrathymic T cell precursor population. J. Immunol. 146, 1387-1393.
2. Adkins B., and Hamilton K. (1994). Developmental ages of the thymic epithelium and of the T cell precursors together determine the proportions of peripheral CD4+ cells. J. Immunol. 153, 5359-5365.
3. lo thymocytes: Expression of CD44, CD25 and early expression of TcRα mRNA. Eur. J. Immunol. 23, 2109-2115.
4. Brocke S., Takacs L., Gerdes J., Osawa H., and Diamantstein T. (1987). The ontogeny of the IL-2R expression and of the IL-2 responsiveness in the rat thymus. Immunobiol. 174, 266-273.
5. Ceredig R. (1990). Intrathymic proliferation of perinatal mouse αβ and γδ T cell receptor-expressing mature T cells. Int. Immunol. 2, 869-867.
6. Ceredig R., Lowenthal J.W., Nabholz M., and MacDonald H.R. (1985). Expression of interleukin 2 receptors as a differentiation marker on intrathymic stem cells. Nature 314, 98-100.
7. + cells from (C57BL/6 × DBA/2)FI mice. Int. Immunol. 2, 869-877.
8. Crook K., and Hunt S.V. (1996). Enrichment of early fetal-liver hemopoietic stem cells of the rat using monoclonal antibodies against the transferrin receptor, Thy-1 and MRC-OX82. Dev. Immunol. 4, 235-246.
9. + cells in vitro. J. Immunol. 147, 4060-4068.
10. Fedecka-Brunner B., Penninger J., Vaigot P., Lehman A., Martinez A. C., and Kroemer F. (1991). Development expression of IL-2R light chain (CD25) in the chicken embryo. Dev. Immunol. 1, 237-242.
11. Fowlkes B.J., Kruisbeek A., Ton-That H., Weston M.A., Coligan J.E., Schwartz R.H., and Pardoll D.M. (1987). A novel population of T-cell receptor αβ-bearing which predominantly expresses a single Vβ gene family. Nature 329, 251-253.
12. Godfrey D.I., Kennedy J., Suda T., and Zlotnik A. (1993). A development pathway involving four phenotypically and functional distinct subsets of CD3-4-8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150, 4244-4252.
13. Goff L.K., Larsson L., and Fisher A.G. (1990). Expression of high molecular weight isoforms of CD45 by mouse thymic progenitor cells. Eur. J. Immunol. 20, 665-671.
14. Gotlieb W.H., Bristol L.A., Weissman A.M., Durum S.K., Tackacs L. (1993). Up-regulation of T cell receptor γ-chain transcription by interleukin-2. Cell. Immunol. 151, 345-350.
15. Groettnrup M., Undewiss K., Azogni R., Owen M.J., Harday A.C., and von Boehmer H. (1993). A novel disulfide-linked heterodimer on pro-T cells consist of the T-cell receptor β chain and a 33KD glycoprotien. Cell 75, 283-294.
16. Habu S., Okumura K., Diamantein T., and Shevach E.M. (1985). Expression of IL-2R on murine fetal thymocytes. Eur. J. Immunol. 15, 456-460.
17. Haynes B.F., and Heinly C.S. (1995). Early human T cell development: Analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment. J. Exp. Med. 181, 1445-1458.
18. He W., and Kabelitz D. (1993). Differential effects of interleukin-7 and interleukin-2 on T-cell receptor γδ-expressing cells within CD4-CD8- postnatal human thymocytes. Int. Arch. Allergy Immunol. 102, 321-326.
19. Hosseinzadeh H., and Goldschneider Y. (1993). Recent thymic emigrants in the rat express a unique antigenic phenotype and undergo post-thymic maturation in peripheral lymphoid tissues J. Immunol. 150, 1670-1679.
20. Hünig T., Tiefenthaler G., Schlipköter E., and Lawetzky A. (1989a). The T-cell antigen receptor and CD2 in rat T-cell activation and ontogeny. In Progress in Immunology, Melchers F., Ed. (Berlín: Springer-Verlag), pp. 139-146.
21. Hünig T., Wallny H.-J., Hartley J.K., Lawetzky A., and Tiefenthaler G. (1989b). A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. J. Exp. Med. 169, 73-86.
22. Jotereau F., Henze F., Salomon-Vie V., and Gascan H. (1987). Cell kinetics in the fetal mouse thymus: Precursor cell input, proliferation and emigration. J. Immunol. 138, 1026-1030.
23. Kampinga J., and Aspinall R. (1990). Thymocyte differentiation and thymic microenvironment development in the fetal rat thymus: An immunohistological approach. In Thymus Uptade, Kendall, M. D., and Ritter, M., Eds. (London: Harwood Academic Publishers), pp. 149-186.
24. Kondo M., Takeshita T., Ishii N., Nakamura M., Watanabe S., Arai K., and Sagamura K. (1993). Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science 262, 1874-1877.
25. Law D.A., Spruyt L.L., Paterson D.J., and Williams A.F. (1989). Subsets of thymopoietic rat thymocytes defined by expression of the CD2 antigen and MRC OX22 determinant of the leukocytecommon antigen CD45. Eur. J. Immunol. 19, 2289-2295.
26. Lawetzky A., Kubbies M., and Hünig T. (1991). Rat first-wave mature thymocytes: Cycling lymphoblast that are sensible to activation-induced cell death but rescued by IL-2. Eur. J. Immunol. 21, 2599-2604.
27. Levelt C.N., and Eichmann K. (1995). Receptors and signals in early thymic selection. Immunity 3, 667-672.
28. Mertsching E., and Ceredig R. (1996). T cell receptor-γδ-expressing fetal mouse thymocytes are generated without T cell receptor Vβ selection. Eur. J. Immunol. 26, 804-810.
29. Modigliani Y., Coutinho G., Burlen-Defranoux O., Coutinho A., and Bandeira A. (1994). Differential contribution of thymic outputs and peripheral expansion in the development of peripheral T cell pool. Eur. J. Immunol. 24, 1223-1227.
30. Park I.-H., and Hünig T. (1995). Regulation of RAG-1, TcR, and IL-2RmRNA expression in a cohort of synchronously differentiating rat CD4+CD8+ thymocytes. The 9th International Congress of Immunology, Abstract A-2945. San Francisco, July 23-25, 1995. San Francisco: American Association of Immunologists p. 497.
31. Paterson D.J., and Williams A.F. (1987). An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen. J. Exp. Med. 166, 1603-1608.
32. Penit C., and Vasseur F. (1989). Cell proliferation and differentiation in the fetal and early postnatal mouse thymus. J. Immunol. 142, 3369-3377.
33. Ritter M.A., Gordon L.K., and Goldschneider I. (1978). Distribution and identification of Thy 1 bearing cells ontogeny in rat hemopoietic and lymphoid tissues. J. Immunol. 121, 2463-2471.
34. Shortman K., and Wu L. (1996). Early T lymphocyte progenitors. Annu. Rev. Immunol. 14, 29-47.
35. Takacs L., Ruscetti F.W., Kovacs E.J., Rocha B., Brocke S., Diamantstein T., and Mathieson B.J. (1988). Immature double negative (CD4-CD8-) rat thymocytes do not express IL-2 receptors. J. Immunol. 141, 3810-3818.
36. Toribio M.L., Gutierrez J.C., Pezzi L., Marcos M.A., and Martinez A.C. (1989). Interleukin-2-dependent autocrine proliferation in T-cell development. Nature 342, 82-85.
37. Varas A., Vicente A., Jiménez E., Alonso L., Moreno J., Muñóz J.J., Zapata A.G. (1997a). Interleukin-7 treatment promotes the differentiation pathway of T-cell-receptor-αβ cells selectively to the CD8+ cell lineage. Immunology 92, 457-464.
38. Varas A., Vicente A., Romo T., and Zapata A.G. (1997b). Role of IL-2 in rat fetal thymocyte development. Int. Immunol. 9, 1589-1599.
39. Vicente A., Varas A., Alonso L., Gómez del Moral M., and Zapata A.G. (1994). Ontogeny of rat thymic dendritic cells. Immunology 82, 75-81.
40. Vicente A., Varas A., Moreno J., Sacedón R., Jiménez E., and Zapata A.G. (1995). Ontogeny of rat thymic macrophages: Phenotypic characterization and possible relationships between different cell subsets. Immunology 85, 99-105.
41. Vicente A., Varas A., Sacedón R., and Zapata A.C. (1996). Histogenesis of the epithelial component of rat thymus: An ultrastructural and immunohistological analysis. The Anatom. Rec. 244, 506-519.
42. Weissman I.L. (1967). Thymus cell migration. J. Exp. Med. 126, 291-294.
43. Wilson A., and MacDonald H.R. (1995). Expression of genes encoding the pre-TcR and CD3 complex during thymus development. Int. Immunol. 7, 1659-1664.
44. Zuñiga-Pflücker J.C., and Lenardo M.J. (1996). Regulation of thymocyte development from immature progenitors. Curr. Opin. Immunol. 8, 215-224.