Postmortem instability of dopamine and its metabolites in rat striatum and limbic forebrain

Polish Journal of Pharmacology

Volumn 50, Issue 6, 1998, Pages 425-429

  Karolewicz, Beata ^a   Romańska, Irena ^a   Antkiewicz Michaluk, Lucyna ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

3,4 Dihydroxyphenylacetic acid (DOPAC); 3 Methoxytyramine (3 MT); Dopamine metabolism; High performance liquid chromatography (HPLC); Homovanillic acid (HVA); Postmortem studies

Indexed keywords

3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; DOPAMINE; HOMOVANILLIC ACID; NEUROTRANSMITTER;

ACCURACY; AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CADAVER; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE METABOLISM; DYNAMICS; ELECTROCHEMICAL DETECTION; FOREBRAIN; FROZEN SECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMBIC CORTEX; MALE; MEASUREMENT; NONHUMAN; NUCLEUS ACCUMBENS; OLFACTORY NUCLEUS; RAT; TEMPERATURE;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; AUTOPSY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYOPRESERVATION; DOPAMINE; DRUG STABILITY; HOMOVANILLIC ACID; LIMBIC SYSTEM; MALE; RATS; RATS, WISTAR; TIME FACTORS; VISUAL CORTEX;

EID: 0032458030     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Agid Y., Javoy F., Youdim M. B. H.: Monoamine oxidase and aldehyde dehydrogenase activity in the striatum of rats after 6-hydroxydopamine lesion of the nigrostriatal pathway. Brit. J. Pharmacol.,1973, 48, 175-178.
2. Carlsson A., Lindqvist M., Kehr W.: Postmortal accumulation of 3-methoxytyramine in brain. Naunyn-Schmied. Arch. Pharmacol.,1974, 284, 365-372.
3. Fahn S., Davis J. N., Rowland L. P.: Cerebral hypoxia and its consequences. In: Advances in Neurology, Raven Press, New York, 1979, 26, 454.
4. Ganrot P. O., Rosengren E., Gottfries C. G.: Effect of iproniazid on monoamines and monoamine oxidase in human brain. Experientia, 1962, 18, 260-261.
5. Heal D. J., Frankland A. T. J., Buckett W. R.: A new and highly sensitive method for measuring 3-methoxytyramine using HPLC with electrochemical detection. Studies with drugs which alter dopamine metabolism in the brain. Neuropharmacology, 1990, 29, 1141-1150.
6. Kaplan G. P., Hartman B. K., Creveling C. R.: Immunohistochemical demonstration of catechol-O-methyltransferase in mammalian brain. Brain Res.,1979, 167, 241-250.
7. Kehr W.: 3-Methoxytyramine as an indicator of impulse-induced dopamine release in rat brain in vivo. Naunyn-Schmied. Arch. Pharmacol.,1976, 293, 209-215.
8. Kehr W.: 3-Methoxytyramine and normetanephrine as indicator of dopamine and noradrenaline release in mouse brain in vivo. J. Neural Transm.,1981, 50, 165-178.
9. Lehninger A. L.: The molecular basis of cell structure and function. In: Biochemistry, Worth Publishers, New York, 1970, 509-542.
10. Ljunggren B., Schutz H., Siesjo B. K.: Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia. Brain Res.,1974, 73, 277-289.
11. Moleman P., Bruinvels J., Westerink B. H. C.: Rapid postmortem changes in 3,4-dihydroxyphenylacetic acid (DOPAC), a dopamine metabolite, in rat striatum. J. Neurochem.,1977, 29, 175-177.
12. Phebus L. A., Perry K. W., Clemens J. A., Fuller R. W.: Brain anoxia releases striatal dopamine in rat brain. Life Sci.,1986, 38, 2447-2454.
13. Siesjo B. K., Nordstrom C. H.: Brain metabolism in relation to oxygen supply. In: Oxygen and Physiological Function. Ed. Jobsis F. F., Dallas, 1977, 459-479.
14. Utresky N. J., Iversen L. L.: Effects of 6-hydroxydopamine on catecholamine-containing neurones in the rat brain. J. Neurochem.,1970, 17, 269-278.
15. Vogel W. H., Orfel V., Century B.: Activites of enzymes involved in the formation and destruction of biogenic amines in various areas of human brain. J. Pharmacol. Exp. Ther.,1969, 165, 169-203.
16. Vulto A. B., Sharp T., Ungerstedt U., Versteeg D. H. G.: Rapid postmortem increase in extracellular dopamine in the rat brain as assessed by brain microdialysis. J. Neurochem.,1988, 51, 764-749.
17. Vulto A. G., Westenberg H. G. M., Meijer L. B. A., Versteeg D. H. G.: The dopamine metabolite 3-methoxytyramine is not a suitable indicator of dopamine release in the rat brain. J. Neurochem.,1986, 47, 1387-1393.
18. Wiesel F.A., Sedvall G.: Post-mortal changes of dopamine and homovanillic acid levels in rat striatum as measured by mass fragmentography. Brain Res.,1974, 65, 547-550.