Treatment of acute gynecologic infections with trovafloxacin

American Journal of Surgery

Volumn 176, Issue 6 A, 1998, Pages 67S-73S

  Roy, Subir ^a   Koltun, William ^b   Chatwani, Ashwin ^c   Martens, Mark G ^d   Dittrich, Richard ^e   Luke, David R ^f  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b S Diego Ctr for Women Clin Res   (United States)

^c TEMPLE UNIVERSITY HOSPITAL   (United States)

^d HENNEPIN COUNTY MEDICAL CENTER   (United States)

^e HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^f PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALATROFLOXACIN; AMOXICILLIN PLUS CLAVULANIC ACID; CEFOXITIN; TROVAFLOXACIN;

ADULT; ANTIBIOTIC THERAPY; ANTIMICROBIAL ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; FEMALE; GYNECOLOGIC INFECTION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT FAILURE;

EID: 0032457927     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9610(98)00223-2     Document Type: Article

References (33)

1. Thadepalli H, Mathai D, Scotti R, et al. Ciprofloxacin monotherapy for acute pelvic infections: a comparison with clindamycin plus gentamicin. Obstet Gynecol 1991;78:696-702.
2. Crombleholme WR, Ohm-Smith M, Robbie MO, et al. Ampicillin/sulbactam versus metronidazole-gentamicin in the treatment of soft tissue pelvic infections. Am J Obstet Gynecol 1987;156:507-512.
3. Larsen JW, Gabel-Hughes K, Kreter B. Efficacy and tolerability of imipenem-cilastatin versus clindamycin + gentamicin for serious pelvic infections. Clin Ther. 1992;14:90-96.
4. Sweet RL, Roy S, Faro S, et al. Piperacillin and tazobactam versus clindamycin and gentamicin in the treatment of hospitalized women with pelvic infection. Obstet Gynecol. 1994;83:280-286.
5. Gall S. Therapeutic dilemmas in the treatment of pelvic infections. J Reprod Med. 1990;35(suppl 11):1091-1094.
6. Faro S. Ticarcillin/clavulanate: an alternative to combination antibiotic therapy for treating soft tissue pelvic infections in women. J Reprod Med. 1990;35(suppl 3):353-358.
7. Stein GE. Patient costs for prophylaxis and treatment of obstetric and gynecologic surgical infections. Am J Obstet Gynecol. 1991; 164:1377-1380.
8. Sweet RL. Role of cephamycins in obstetrics and gynecology. J Reprod Med. 1990;35(suppl 11):1064-1069.
9. Neu HC, Chin N-X. In vitro activity of the new fluoroquinolone CP-99,219. Antimicrob Agents Chemother. 1994;38:2615-2622.
10. Eliopoulos GM, Klimm K, Eliopoulos CT, et al. In vitro activity of CP-99,219, a new fluoroquinolone, against clinical isolates of gram-positive bacteria. Antimicrob Agents Chemother. 1993;37:366-370.
11. Cormican MG, Jones RN. In-vitro activity of trovafloxacin (CP99,219) tested by two methods against 150 vancomycin-resistant enterococcal isolates. J Antimicrob Chemother. 1996;37:847-849.
12. Wexler HM, Molitoris E, Molitoris D, Finegold SM. In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria. Antimicrob Agents Chemother. 1996;40:2232-2235.
13. Vincent J, Venitz J, Teng R, et al. Pharmacokinetics and safety of trovafloxacin in healthy male volunteers following administration of single intravenous doses of the prodrug, alatrofloxacin. J Antimicrob Chemother. 1997;39(suppl B):75-80.
14. Kerr JR, Barr JG, Smyth ETM, O'Hare J. Technique for calculation of the true costs of antibiotic therapy. Eur J Clin Microbiol Infect Dis. 1992;11:823-827.
15. Moran RM, Brett JL, Wulf PH. Evaluating the cost impact of intravenous antibiotic dosing frequencies. DICP Ann Pharmacother. 1991;25:546-552.
16. Hemsell DL, Solomkin JS, Tally F, Bartlett JG. Evaluation of new anti-infective drugs for the treatment of acute pelvic infections in hospitalized women. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992;15(suppl 1):S43-S52.
17. Martens MG, Faro S, Hammill HA, et al. Transcervical uterine cultures with a new endometrial suction curette: a comparison of three sampling methods in postpartum endometritis. Obstet Gynecol 1989;74:273-276.
18. Williams DJ, Hopkins S. Safety and tolerability of intravenous to oral treatment and single dose intravenous or oral prophylaxis with trovafloxacin. Am J Surg. 1998;176(Suppl 6A):74S-79S.
19. Hager WD, McDaniel PS. Treatment of serious obstetric and gynecologic infections with cefoxitin. J Reprod Med. 1983;28:337-340.
20. Hemsell DL, Wendel GD, Gall SA, et al. Multicenter comparison of cefotetan and cefoxitin in the treatment of acute obstetric and gynecologic infections. Am J Obstet Gynecol. 1988;158:722-727.
21. Lucas MJ, Cox SM, Roark ML, Cunningham FG. Ticarcillin/ clavulanate in the treatment of pelvic infections. J Reprod Med. 1990;35(suppl 3):343-347.
22. Zambrano D. Recent advances in antibiotic regimens for the treatment of obstetric-gynecologic infections. Clin Ther. 1996;18: 214-227.
23. Faro S. Antibiotic usage in pelvic infections: an overview. J Reprod Med. 1988;33(suppl 6):566-570.
24. Hemsell DL, Hemsell PG, Heard MC, Nobles BJ. Piperacillin and a combination of clindamycin and gentamicin for the treatment of hospital and community acquired acute pelvic infections including pelvic abscess. Surg Gynecol Obstet. 1987;165:223-229.
25. Gall SA, Kohan AP, Ayers OM, et al. Intravenous metronidazole or clindamycin with tobramycin for therapy of pelvic infections. Obstet Gynecol. 1981;57:51-58.
26. Knuppel RA, O'Bryan D, Lake M. Cefotetan: comparative and noncomparative studies in obstetric and gynecologic infections. South Med J. 1988;81:185-188.
27. Gunning JE. A comparison of piperacillin and clindamycin plus gentamicin in women with pelvic infections. Surg Gynecol Obstet. 1986;163:156-162.
28. Donahue PE, Smith DL, Yellin AE, et al. Trovafloxacin in the treatment of intra-abdominal infections: results of a double-blind, multicenter comparison with imipenem/cilastatin. Am J Surg. 1998; 176(Suppl 6A):53S-61S.
29. Sweet R, Gibbs R. Intraamniotic infection (intrauterine infection in late pregnancy). In: Infectious Diseases of the Female Genital Tract, 2nd ed. Baltimore: Williams & Wilkins; 1990:334-347.
30. Just PM. Overview of the fluoroquinolone antibiotics. Pharmacotherapy. 1993;13(2 pt 2):4S-17S.
31. Teng R, Dogolo LC, Willavize SA, et al. Effect of Maalox and omeprazole on the bioavailability of trovafloxacin. J Antimicrob Chemother. 1997;39(suppl B):93-97.
32. Vincent J, Teng R, Dogolo LC, et al. Effect of trovafloxacin, a new fluoroquinolone antibiotic, on the steady-state pharmacokinetics of theophylline in healthy volunteers. J Antimicrob Chemother. 1997;39(suppl B):81-86.
33. Braveman P, Schaaf VM, Egerter S, et al. Insurance-related differences in the risk of ruptured appendix. N Engl J Med. 1994; 331:444-449.