Simultaneous evaluations of contractility and energy metabolism of stunned myocardium using 31P magnetic resonance spectroscopy

Japanese Heart Journal

Volumn 39, Issue 6, 1998, Pages 791-807

  Geshi, Eiichi ^a   Sordahl, Louis A ^b   Ito, Seiji ^a   Umetsu, Kazuhiko ^a   Katagiri, Takashi ^a  

^a SHOWA UNIVERSITY   (Japan)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

31PMRS; Creatine; High energy phosphate; Kinase; Regional contractility; Stunned myocardium; Whole body dog heart

Indexed keywords

CREATINE KINASE; CREATINE PHOSPHATE; PHOSPHATE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ELECTROCARDIOGRAM; ENERGY METABOLISM; ENERGY TRANSFER; ENZYME ACTIVITY; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 0032457392     PISSN: 00214868     EISSN: None     Source Type: Journal    
DOI: 10.1536/ihj.39.791     Document Type: Article

References (41)

1. Braunwald E, Kloner RA. The stunned myocardium: Prolonged, postischemic ventricular dysfunction. Circulation 1982; 66: 1146-9.
2. Bolli. Mechanism of myocardial "stunning". Circulation 1990; 82: 723-38.
3. Zucchi R, Yu G, Ronca-Testoni S, Mariani M, Ronca G. Energy metabolism in myocardial stunning. J Mol Cell Cardiol 1992; 24: 1237-52.
4. Opie LH. Chronic stunning: the new switch in thought. Basic Res Cardiol 1995; 90: 303-4.
5. Tillsch J, Brunken R, Marshall R, et al. Reversibility of cardiac wall-motion abnormalities predicted by positron tomography. N Engl J Med 1986; 314: 884-8.
6. Wijns W, Vatner SF, Camici PG. Hibernating myocardium. N Engl J Med 1998; 339: 173-81.
7. Reimer KA, Hill ML, Jennings RB. Prolonged depletion of ATP and of the adenine nucleotide pool due to delayed resynthesis of adenine nucleotides following reversible myocardial ischemic injury in dogs. J Mol Cell Cardiol 1982; 13: 229-39.
8. Swain JL, Sabina RL, McHale PA, Greenfield JC Jr, Holmes EW. Prolonged myocardial nucleotide depletion after brief ischemia in the open-chest dog. Am J Physiol 1982; 242: H818-26.
9. Greenfield RA, Swain JL. Disruption of myofibrillar energy use: dual mechanisms that may contribute to postischemic dysfunction in stunned myocardium. Circ Res 1987; 60: 283-9.
10. Flameng W, Andres J, Ferdinande P, Mattheussen M, Van Belle H. Mitochondrial function in myocardial stunning. J Mol Cell Cardiol 1991; 23: 1-11.
11. Taegtmeyer H, Roberts AFC, Raine AEG. Energy metabolism in reperfused heart muscle: metabolic correlates to return of function. J Am Coll Cardiol 1985; 6: 864-70.
12. Asimakis GK, Zwischenberger JB, Inners-McBride K, Sordahl LA, Conti VR. Postischemic recovery of mitochondrial adenine nucleotides in the heart. Circulation 1992; 85: 2212-20.
13. Przyklenk K, Kloner RA. What factors predict recovery of contractile function in the canine model of the stunned myocardium? AmJ Cardiol 1989; 64: 18F-26F.
14. Saeed M, Wendland MF, Wagner S, Derugin N, Higgins CB. Preservation of high-energy phosphate reserves in a cat model of post-ischemic myocardial dysfunction. Invest Radiol 1992; 27: 145-52.
15. Guth BD, Martin JF, Heusch G, Ross J Jr. Regional myocardial blood flow, function and metabolism using phosphorous-31 nuclear magnetic resonance spectroscopy during ischemia and reperfusion in dogs. J Am Coll Cardiol 1987; 10: 673-81.
16. Camacho SA, Lanzer P, Toy BJ, et al. In vivo alterations of high-energy phosphates and intracellular pH during reversible ischemia in pigs: a 31P magnetic resonance spectroscopy study. Am Heart J 1988; 116: 701-8.
17. Neubauer S, Hamman BL, Perry SB, Bittl JA, Ingwall JS. Velocity of the creatine kinase reaction decreases in postischemic myocardium: a 31P-NMR magnetization transfer study of the isolated ferret heart. Circ Res 1988; 63: 1-15.
18. Schaefer S, Schwartz GG, Gober JR, et al. Relationship between myocardial metabolites and contractile abnormalities during graded regional ischemia. J Clin Invest 1990; 85: 706-13.
19. Schwartz GG, Shaefer S, Meyerhoff DJ, et al. Dynamic relation between myocardial contractility and energy metabolism during and following a brief coronary occlusion in the pig. Circ Res 1990; 67: 490-500.
20. Miller DD, Salinas F, Walsh RA. Simultaneous cardiac mechanics and phosphorus-31 NMR spectroscopy during global myocardial ischemia and reperfusion in the intact dog. Mag Reson Med 1991; 17: 41-52.
21. Yoshiyama M, Ishikawa M, Miura I, Takeuchi K, Takeda T. Time course of the recovery of adenosine triphosphate content with adenosine in post-ischemic heart: a 31P magnetic resonance spectroscopy study. Jpn Circ J 1994: 58: 662-70.
22. Zhang J, Wilke N, Wang Y, et al. Functional and bioenergetic consequences of postinfarction left ventricular remodeling in a new porcine model MRI and 31P-MRS study. Circulation 1996; 94: 1089-100.
23. Hartley CJ, Hanley HG, Lewis RM, Cole JS. Synchronized pulsed Doppler blood Row and ultrasonic dimension measurement in conscious dogs. Ultrasound Med Biol 1987; 4: 99-110.
24. Fralix TA, Balaban RS. NMR spectroscopy of the heart: Part II. Concept Mag Reson 1989; 1: 93-108.
25. Vandegaer KM, Jacobus WE. Evidence against direct transfer of adenine nucleotides by the heart mitochondrial creatine kinase-adenine nucleotide translocase process. Biochem Biophys Res Comm 1982; 109: 442-8.
26. Bolli R, Zhu W, Thomby JI, ONeill PG, Roberts R. Time course and determinants of recovery of function after reversible ischemia in conscious dogs. AmJ Physiol 1988; 254: H102-4.
27. Zhang J, Wilke N, Wang Y, et al. Functional and bioenergetic consequences of postinfarction left ventricular remodeling in a new porcine model: MRI and 31P-MRS study. Circulation 1996; 94: 1089-100.
28. Lewandowski ED, Devous MD Sr, Nunnally RL. High-energy phosphates and function in isolated, working rabbit hearts. AmJ Physiol 1987; 253: H1215-23.
29. Zimmer SD, Ugurbil K, Michurski SP, et al. Alterations in oxidative function and respiratory regulation in the post-ischemia myocardium. J Biol Chem 1989; 264: 12402-11.
30. Heineman FW, Balaban RS. Phosphorous-31 nuclear magnetic resonance analysis of transient changes of canine myocardial metabolism in vivo. J Clin Invest 1990; 85: 843-52.
31. Bittl JA, Balschi JA, Ingwall JS. Contractile failure and high-energy phosphate turnover during hypoxia: 31P-NMR surface coil studies in living rat. Circ Res 1987; 60: 871-8.
32. Greenfield RA, Swain JL. Disruption of myofibrillar energy use: Dual mechanism that may contribute to postischemic dysfunction in stunned myocardium. Circ Res 1987; 60: 283-9.
33. Geshi E, Konno N, Yanagishita T, Katagiri T. Impairment of mitochondrial respiratory activity in the early ischemic myocardium. Jpn Circ J 1988; 52: 535-42.
34. Flameng W, Andres J, Ferdinande P, Mattheussen M, Von Belle H. Mitochondrial function in myocardial stunning. J Mol Cell Cardiol 1991; 23: 1-11.
35. Pantely GA, Malone SA, Rhen WS, et al. Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia. Circ Res 1990; 67: 1481-93.
36. Bolli R. Myocardial "stunning" in man. Circulation 1992; 86: 1671-91.
37. Johnson LL, Verdesca SA, Aude WY, et al. Post ischemic stunning can affect left ventricular ejection fraction and regional wall motion on post-stress gated sestamibi tomograms. J Am Coll Cardiol 1997; 30: 1641-8.
38. Tsubokawa A, Lee J, Shimizu H, et al. Recovery of perfusion, glucose utilization and fatty acid utilization in stunned myocardium. J Nucl Med 1997; 38: 1835-7.
39. 13N] ammonia positron emission tomography. Jpn Circ J 1997; 61: 665-72.
40. Banerjee A, Grosso MA, Brown JM, Rogers KB, Whitman GJR. Oxygen metabolite effects on creatine kinase and cardiac energetics after reperfusion. Am J Physiol 1991; 261: H590-7.
41. Mekhfi H, Veksler V, Mateo P, Maupoli V, Rochette L, Ventura Clapier R. Creatine kinase is the major target of reactive oxygen species in cardiac myofibrils. Circ Res 1996; 78: 1016-27.