Superiority of combined CK-MB and troponin I measurements for the early risk stratification of unselected patients presenting with acute chest pain

Cardiology

Volumn 90, Issue 4, 1998, Pages 286-294

  Meyer, Thomas ^a   Binder, Lutz ^a   Graeber, Tobias ^a   Luthe, Hilmar ^a   Kreuzer, Heinrich ^a   Oellerich, Michael ^a   Buchwald, Arnd B ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Angina pectoris; Chest pain; Risk stratification; Troponin I

Indexed keywords

CREATINE KINASE MB; TROPONIN I;

ACUTE HEART INFARCTION; ADULT; AGED; ANALYZER; ARTICLE; CLINICAL TRIAL; DIAGNOSTIC VALUE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; RECURRENT DISEASE; RISK ASSESSMENT; THORAX PAIN; UNSTABLE ANGINA PECTORIS;

AGED; CHEST PAIN; COHORT STUDIES; CORONARY DISEASE; CREATINE KINASE; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; SURVIVAL RATE; TROPONIN I;

EID: 0032452305     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000006860     Document Type: Article

References (17)

1. Giri S, Waters DD: Pathophysiology and initial management of the acute coronary syndromes. Curr Opin Cardiol 1996;11:351-360.
2. Adams JE, Schechtman KB, Landt Y, Ladenson JH, Jaffe AS: Comparable detection of acute myocardial infarction by creatine kinase MB isoenzyme and cardiac troponin I. Clin Chem 1994;40:1291-1295.
3. Bertinchant J-P, Larue C, Pernel I, Ledermann B, Fabbro-Peray P, Beck L, Calzolari C, Trinquier S, Nigond J, Pau B: Release kinetics of serum cardiac troponin I in ischemic myocardial injury. Clin Biochem 1996;29:587-594.
4. Cummins B, Auckland ML, Cummins P: Cardiac-specific troponin-I radioimmunoassay in the diagnosis of acute myocardial infarction. Am Heart J 1987;113:1333-1344.
5. Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T: Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 1997;337:1648-1653.
6. Jaffe AS, Landt Y, Parvin CA, Abendschein DR, Geltman EM, Ladenson JH: Comparative sensitivity of cardiac troponin I and lactate dehydrogenase isoenzymes for diagnosing acute myocardial infarction. Clin Chem 1996; 42:1770-1776.
7. Kuhr LP, Baum H, Schweigert R, Hafner G, Prellwitz W, Neumeier D: Evaluation of a rapid, quantitative cardiac troponin I immunoassay. Eur J Clin Chem Clin Biochem 1997;35: 399-404.
8. Lüscher MS, Thygesen K, Ravkilde J, Heickendorff L: Applicability of cardiac troponin T and I for early risk stratification in unstable coronary artery disease. Circulation 1997;96:2578-2585.
9. Cummins P, Young A, Auckland ML, Michie CA, Stone PCW, Shepstone BJ: Comparison of serum cardiac specific troponin-I with creatine kinase, creatine kinase-MB isoenzyme, tropomyosin, myoglobin and C-reactive protein release in marathon runners: Cardiac or skeletal muscle trauma? Eur J Clin Invest 1987;17: 317-324.
10. Davies E, Gawad Y, Takahashi M, Shi Q, Lam P, Styba G, Lau A, Heeschen C, Usategui M, Jackowski G: Analytical performance and clinical utility of a sensitive immunoassay for determination of human cardiac troponin I. Clin Biochem 1997;30:479-490.
11. Katrukha AG, Bereznikova AV, Esakova TV, Pettersson K, Lövgren T, Severina ME, Pulkki K, Vuopio-Pulkki LM, Gusev NB: Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 1997;43:1379-1385.
12. Antman EM, Tanasijevic MJ, Thompson B, Schactman M, McCabe CH, Cannon CP, Fischer GA, Fung AY, Thompson C, Wybenga D, Braunwald E: Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996;335:1342-1349.
13. Ossendorf M, Eberle B, Ehrenthal W, Rupprecht H-J, Mayer E, Kumpmann K, Hafner G, Prellwitz W: Analytical and clinical evaluation of the access troponin I immunoassay. Clin Lab 1997;43:627-636.
14. Panteghini M, Bonora R, Pagani F: Rapid and specific immunoassay for cardiac troponin I in the diagnosis of myocardial damage. Int J Clin Lab Res 1997;27:60-64.
15. Galvani M, Ottani F, Ferrini D, Ladenson JH, Destro A, Baccos D, Rusticali F, Jaffe AS: Prognostic influence of elevated values of cardiac troponin I in patients with unstable angina. Circulation 1997;95:2053-2059.
16. Wu AHB, Feng YJ, Contois JH, Azar R, Waters D : Prognostic value of cardiac troponin I in patients with chest pain. Clin Chem 1996;42: 651-652.
17. Kollef MH, Ladenson JH, Eisenberg PR: Clinically recognized cardiac dysfunction. An independent determinant of mortality among critically ill patients. Is there a role for serial measurement of cardiac troponin I? Chest 1997; 111:1340-1347.