Determination of the pH gradient across the stratum corneum

Journal of Investigative Dermatology Symposium Proceedings

Volumn 3, Issue 2, 1998, Pages 110-113

  Turner, Norris G ^a,c   Cullander, Christopher ^a   Guy, Richard H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Campus Universitaire   (France)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Barrier function; Confocal microscopy; Skin pH; Stratum corneum

Indexed keywords

CARBOXY SEMINAPHTHORHODAFLUOR 1; FLUORESCENT DYE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; LASER MICROSCOPY; MOUSE; NONHUMAN; NUDE MOUSE; PH; PKA; STRATUM CORNEUM;

EID: 0032450677     PISSN: 10870024     EISSN: None     Source Type: Journal    
DOI: 10.1038/jidsymp.1998.23     Document Type: Article

References (6)

1. Bassnett S, Reinisch L, Beebe DC: Intracellular pH measurement using single excitation-dual emission fluorescence ratios. Am J Physiol 258:C171-C178, 1990
2. Buckler K, Vaughan-Jones R: Application of a new pH-sensitive fluoroprobe (carboxy SNARF-1) for intracellular pH measurement in small, isolated cells. Pflugers Arch 417:234-239, 1990
3. Green PG, Hinz RS, Cullander C, Yamane G, Guy RH: Iontophoretic delivery of amino acids and amino acid derivatives across the skin in vitro. Pharm Res 8:1113-1119, 1991
4. Haugland R: pH Indicators. In: Molecular Probes Catalogue. 1992-94. pp. 129-139
5. Öhman H, Vahlquist A: In vivo studies concerning a pH gradient in human stratum corneum and upper epidermis. Acta Derm Venereol 74:375-379, 1994
6. Sage BH, Hoke RA, McFarland AC, Kowalczyk K: The importance of skin pH in the iontophoresis of peptides. In: Prediction of Percutaneous Penetration, 1993, pp. 410-418