Simulations on the selectivity of 5-aminolaevulinic acid-induced fluorescence in vivo

Journal of Photochemistry and Photobiology B: Biology

Volumn 47, Issue 2-3, 1998, Pages 121-128

  Ackermann, G ^a   Abels, C ^a   Baumler W ^a   Langer, S ^b   Landthaler, M ^a   Lang, E W ^a   Szeimies, R M ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Aminolaevulinic acid (ALA); Compartment model; Pharmacokinetics; Protoporphyrin IX; Topical

Indexed keywords

AMINOLEVULINIC ACID; DIMETHYL SULFOXIDE; FERROCHELATASE; PHOTOSENSITIZING AGENT; PORPHYRIN; PROTOPORPHYRIN; WATER OIL CREAM;

ADULT; AGED; AMELANOTIC MELANOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL CARCINOMA; CLINICAL ARTICLE; DRUG FORMULATION; FLUORESCENCE; GEL; HUMAN; HUMAN TISSUE; KINETICS; NONHUMAN; PH; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SIMULATION; SKINFOLD; STRATUM CORNEUM; SYRIAN HAMSTER;

AMINOLEVULINIC ACID; ANIMALS; CRICETINAE; FLUORESCENCE; HUMANS; MALE; MESOCRICETUS; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MODELS, BIOLOGICAL; PHOTOSENSITIZING AGENTS;

EID: 0032450209     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1011-1344(98)00210-3     Document Type: Article

References (28)

1. [1] J.C. Kennedy, R.H. Pettier, Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy, J. Photochem. Photobiol. B: Biol. 14 (1992) 275-292.
2. [2] Q. Peng, T. Warloe, J. Moan, H. Heyerdahl, H.B. Steen, J.M. Nesland, K.E. Giercksky, Distribution of 5-aminolevulinic acid-induced porphyrins in noduloulcerative basal cell carcinoma, Photochem. Photobiol. 62 (1995) 906-913.
3. [3] A. Martin, W.D. Tope, J.M. Grevelink, J.C. Starr, J.L. Fewkes, T.J. Flotte, T.F. Deutsch, R.R. Anderson, Lack of selectivity of protoporphyrin IX fluorescence for basal cell carcinoma after topical application of 5-aminolevulinic acid: implications for photodynamic therapy, Arch. Dermatol. Res. 287 (1995) 665-674.
4. [4] C. Fritsch, C. Abels, A.E. Goetz, W. Stahl, K. Bolsen, T. Ruzicka, G. Goerz, H. Sies, Porphyrins preferentially accumulate in a melanoma following intravenous injection of 5-aminolevulinic acid, Biol. Chem. 378 (1997) 51-57.
5. [5] W. Grant, C. Hopper, A.J. MacRoberts, P.M. Speight, S.G. Bown, Photodynamic therapy of oral cancer: photosensitization with systemic aminolaevulinic acid, Lancet 342 (1993) 147-148.
6. [6] R.-M. Szeimies, T. Sassy, M. Landthaler, Penetration potency of topical applied 5-aminolevulinic acid for photodynamic therapy of basal cell carcinoma, Photochem. Photobiol. 59 (1994) 73-76.
7. [7] C. Abels, P. Heil, M. Dellian, G.E.H. Kuhnle, R. Baumgartner, A.E. Goetz, In vivo kinetics and spectra of 5-aminolaevulinic acid-induced fluorescence in an amelanotic melanoma of the hamster, Br. J. Cancer 70 (1994) 826-833.
8. [8] H. Heyerdahl, I. Wang, D.L. Liu, R. Berg, S. Anderson-Engels, Q. Peng, J. Moan, S. Svanberg, K. Svanberg, Pharmacokinetic studies on 5-aminolevulinic acid-induced protoporphyrin IX accumulation in tumour and normal tissue, Cancer Lett. 112 (2) (1997) 225-231.
9. [9] H. Fukuda, A.M.C. Batlle, P.A. Riley, Kinetics of porphyrin accumulation in cultured epithelial cells exposed to ALA, Int. J. Biochem. 25 (1993) 1407-1410.
10. [10] B. Ortel, P.G. Calzavara-Pinton, R.-M. Szeimies, T. Hasan, Perspectives in cutaneous photodynamic sensitization, J. Photochem. Photobiol. B: Biol. 36 (1996) 213-219.
11. [11] M. Bermudez-Moretti, S. Correa-Garcia, C. Stella, E. Ramos, A.M.C. Batlle, Delta-aminolevulinic acid transport in Saccharomyces cerevisiae, Int. J. Biochem. 25 (1993) 1917-1924.
12. [12] M. Navone, C. Polo, A.L. Frisardi, N.E. Andrade, A.M.C. Batlle, Heme biosynthesis in human breast adenocarcinoma - mimetric in vitro studies and some heme enzymic activity levels, Int. J. Biochem. 22 (1990) 1407-1411.
13. [13] N. Rebeiz, C.C. Rebeiz, S. Arkins, K.W. Kelley, C.A. Rebeiz, Photodestruction of tumor cells by induction of endogenous accumulation of protoporphyrin IX: enhancement by 1,10-phenanthroline, Photochem. Photobiol. 55 (3) (1992) 431-435.
14. [14] K. Rittenhouse-Diakun, H. van-Leengoed, J. Morgan, E. Hryhorenko, G. Paszkiewicz, J.E. Whitaker, A.R. Oseroff, The role of transferrin receptor (CD71) in photodynamic therapy of activated and malignant lymphocytes using the heme precursor delta-aminolevulinic acid (ALA), Photochem. Photobiol. 61 (5) (1995) 523-528.
15. [15] H.A. Dailey, A. Smith, Differential interaction of porphyrins used in photoradiation therapy with ferrochelatase, Biochem. J. 223 (1984) 441-445.
16. [16] C. Abels, C. Fritsch, K. Bolsen, R.-M. Szeimies, T. Ruzicka, G. Goerz, A.E. Goetz, Photodynamic therapy with 5-aminolaevulinic acid-induced porphyrins of an amelanotic melanoma in vivo, J. Photochem. Photobiol. B: Biol. 40 (1) (1997) 76-83.
17. [17] B. Endrich, K. Asaishi, A.E. Goetz, K. Meßmer, Technical report: a new chamber technique for microvascular studies in unanaesthetized hamsters, Res. Exp. Med. 177 (1980) 125-134.
18. [18] K. Asaishi, B. Endrich, A.E. Goetz, K. Meßmer, Quantitative analysis of microvascular structure and function in the amelanotic melanoma A-Mel-3, Cancer Res. 41 (1981) 1898-1904.
19. [19] M. Leunig, C. Richert, F. Gamarra, W. Lumpert, E. Vogel, D. Jocham, A.E. Goetz, Tumour localisation kinetics of photofrin and three synthetic porphyrinoids in an amelanotic melanoma of the hamster, Br. J. Cancer 68 (1993) 225-234.
20. [20] N. van der Veen, H.S. de Bruijn, R.J. Berg, W.M. Star, Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice, Br. J. Cancer 73 (1996) 925-930.
21. [21] J. Bedwell, A.J. MacRoberts, D. Phillips, S.G. Brown, Fluorescence distribution and photodynamic effect of ALA-induced PPIX in the DMH rat colonic tumour model, Br. J. Cancer 65 (1992) 818-824.
22. [22] A.C. Allenby, N.H. Creasey, J.A.G. Edington, C. Schock, Mechanism of action of accelerants on skin penetration, Br. J. Dermatol. 81 (1965) (Suppl. 4) 47-55.
23. [23] H.J. Bidmon, J.D. Pitts, H.F. Solomon, J.V. Bondi, W.E. Stumpf, Estradiol distribution and penetration in rat skin after topical application, studied by high resolution autoradiography, Histochemistry 5 (1990) 43-54.
24. [24] D. Dupuis, A. Rougier, R. Rouget, C. Lotte, The measurement of stratum corneum reservoir: a simple method to predict the influence of vehicles on in vivo percutaneous absorption, Br. J. Dermatol. 115 (1986) 233-238.
25. [25] Z. Malik, M. Djaldetti, 5-Aminolevulinic acid stimulation of porphyrin and hemoglobin synthesis by uninduced Friend erythroleukemic cells, Cell-Differ. 8 (1979) 223-233.
26. [26] L.H. Conder, S.I. Woodard, H.A. Dailey, Multiple mechanims for the regulation of haem synthesis during erythroid cell differentiation. Possible role for coproporphyrinogen oxidase, Biochem. J. 275 (1991) 321-326.
27. [27] G.H. Elder, The porphyrias, in: J.B. Holton (Ed.), The Inherited Metabolic Disorders, 2nd ed., Churchill Livingstone, London, 1994.
28. [28] G. Ackermann, Quantitative Bildauswertung und Modellsimulationen zur in vivo-Kinetik der 5-ALA-induzierten Fluoreszenz in Tumoren der Haut, Diploma Thesis, Institute for Biophysics, University of Regensburg, Germany, 1997.