Lipase-catalyzed enantioselective transesterification of cyanohydrins for the synthesis of (S)-α-cyano-3-phenoxybenzyl acetate

Annals of the New York Academy of Sciences

Volumn 864, Issue , 1998, Pages 646-648

  Zhu, Ying ^a   Yang, Li Rong ^a   Zhu, Zi Qiang ^a   Yao, Shanjing ^a   Cen, Peilin ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; ALPHA CYANO 3 PHENOXYBENZYLACETATE; CYANOHYDRIN; IMMOBILIZED ENZYME; NITRILE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

CATALYSIS; CONFERENCE PAPER; ENANTIOMER; ENZYME ACTIVITY; ESTERIFICATION; STEREOCHEMISTRY; SYNTHESIS;

EID: 0032447532     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10397.x     Document Type: Conference Paper

References (3)

1. 1. KLIBANOV, A. M. 1990. Asymmetric transformation catalyzed by enzymes in organic solvents. Acc. Chem. Res. 23: 114-120.
2. 2. VAN ALMSICK, A. et al. 1989. Enzymatic preparation of optically active cyanohydrin acetates. J. Chem. Soc. Chem. Commun., p. 1391-1393.
3. 3. WANG, Y. et al. 1989. Lipase-catalyzed irreversible transesterification using enol esters: resolution of cyanohydrins and syntheses of ethyl (R)-2-hydroxy-4-phenylbutyrate and (S)-propranolol. Tetrahedron Lett. 30: 1917-1920.