Role of galanin in the gastrointestinal sphincters

Annals of the New York Academy of Sciences

Volumn 863, Issue , 1998, Pages 143-155

  Rattan, Satish ^a   Tamura, Wataru ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALANIN;

ANUS SPHINCTER; AUTONOMIC NERVOUS SYSTEM; CONFERENCE PAPER; LOWER ESOPHAGUS SPHINCTER; MYENTERIC PLEXUS; NERVE FIBER; SMOOTH MUSCLE RELAXATION;

EID: 0032447198     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10691.x     Document Type: Conference Paper

References (82)

1. 1. TATEMOTO, K., A. ROKAEUS, H. JORNVALL, T.J. MCDONALD & V. MUTT. 1983. Galanin: A novel biologically active peptide from porcine intestine. FEBS Lett. 164: 124-128.
2. 2. ROKAEUS, A., T. MELANDER, T. HOKFELT, J.M. LUNDBERG, K. TATEMOTO, M. CARLQUIST & V. MUTT. 1984. A galanin-like peptide in the central nervous system and intestine of the rat. Neurosci. Lett. 47: 161-166.
3. 3. GOYAL, R.K. & I. HIRANO. 1996. The enteric nervous system. N. Engl. J. Med. 334: 1106-1115.
4. 4. ROKAEUS, A. 1987. Galanin-a newly isolated biologically active neuropeptide. Trends Neurosci. 10: 158-164.
5. 5. MELANDER, T., T. HOKFELT, A. ROKAEUS, J. FAHRENKRUG, K. TATEMOTO & V. MUTT. 1985. Distribution of galanin-like immunoreactivity in the gastro-intestinal tract of several mammalian species. Cell Tissue Res. 239: 253-270.
6. 6. RATTAN, S. 1991. Role of galanin in the gut. Gastroenterology 100: 1762-1768.
7. 7. EKBLAD, E., R. HAKANSON, F. SUNDLER & C. WAHLESTEDT. 1985. Galanin: Neuromodulatory and direct contractile effects on smooth muscle preparations. Br. J. Pharmacol. 86: 241-246.
8. 8. GOYAL, R.K., S. RATTAN & S.I. SAID. 1980. VIP as a possible neurotransmitter of non-cholinergic non-adrenergic inhibitory neurones. Nature 288: 378-380.
9. 9. BIANCANI, P., J.H. WALSH & J. BEHAR. 1984. Vasoactive intestinal polypeptide: A neurotransmitter for lower esophageal sphincter relaxation. J. Clin. Invest. 73: 963-967.
10. 10. TOTTRUP, A., D. SVANE & A. FORMAN. 1991. Nitric oxide mediating NANC inhibition in opossum lower esophageal sphincter. Am. J. Physiol. 260: G385-G389.
11. 11. RATTAN, S. & R.K. GOYAL. 1987. Effect of galanin on the opossum lower esophageal sphincter. Life Sci. 41: 2783-2790.
12. 12. HARLING, H., T. MESSELL, S.L. JENSEN, J.J. HOLST & S.S. POULSEN. 1989. Occurrence, distribution and motor effects of galanin in the porcine lower esophageal sphincter. Digestion 42: 151-157.
13. 13. LICHTENSTEIN, G.R., J.C. REYNOLDS, C.P. OGOREK & H.P. PARKMAN. 1994. Localization and inhibitory actions of galanin at the feline lower esophageal sphincter. Regul. Pept. 50: 213-222.
14. 14. CHAKDER, S. & S. RATTAN. 1991. Effects of galanin on the opossum internal anal sphincter: Structure-activity relationship. Gastroenterology 100: 711-718.
15. 15. KACZMAREK, J., S. RATTAN & R.K. GOYAL. 1987. Galanin selectively inhibits noncholinergic component of peristalsis in smooth muscle of opossum esophagus (abstr) Gastroenterology 92: 1802.
16. 16. YAMATO, S., I. HIRANO & R.K. GOYAL. 1996. Role of galanin in esophageal peristalsis in opossum in vivo (abstr) Gastroenterology 110: A785.
17. 17. PARKMAN, H.P., J.C. REYNOLDS, C.P. OGOREK & M.S. KREIDER. 1993. Thyrotropin releasing hormone: An inhibitory regulatory peptide of the feline lower esophageal sphincter. Am. J. Physiol. Gastrointest. Liver Physiol. 264: G522-G527.
18. 18. REYNOLDS, J.C., M. DUKEHART, A. OUYANG & S. COHEN. 1986. Interactions of bombesin and substance P at the lower esophageal sphincter. J. Clin. Invest. 77: 436-440.
19. 19. REYNOLDS, J.C., A. OUYANG & S. COHEN. 1984. A lower esophageal sphincter reflex involving substance P. Am. J. Physiol. Gastrointest. Liver Physiol. 256: G345-G354.
20. 20. HE, X.D. & R.K. GOYAL. 1995. Inhibitory junction potential in the mouse pyloric sphincter: Roles of ATP, VIP and NO. Gastroenterology 108: A975.
21. 21. ALLESCHER, H.-D. & E.E. DANIEL. 1994. Role of NO in pyloric, antral, and duodenal motility and its interaction with other inhibitory mediators. Dig. Dis. Sci. 39 (Suppl): 73S-75S.
22. 22. GONDA, T., E.E. DANIEL, T.J. MCDONALD, J.E.T. Fox, B.D. BROOKS & M. OKI. 1989. Distribution and function of enteric GAL-IR nerves in dogs: Comparison with VIP. Am. J. Physiol. 256: G884-G896.
23. 23. DENT, J. & B. CHIR. 1976. A new technique for continuous sphincter pressure measurement. Gastroenterology 71: 263-267.
24. 24. ALUMETS, J., O. SCHAFFALITZKY DE MUCKADELL, J. FAHRENKRUG, F. SUNDLER, R. HAKANSON & R. UDDMAN. 1979. A rich VIP nerve supply is characteristic of sphincters. Nature 280: 155-156.
25. 25. TANGE, A. 1983. Distribution of peptide-containing endocrine cells and neurons in the gastrointestinal tract of the dog: Immunocytochemical studies using antisera to somatostatin, substance P, vasoactive intestinal polypeptide, metenkephalin and neurotensin. Biomed. Res. 4: 9-14.
26. 26. ALLESCHER, H.D., J. DENT, E.E. DANIEL, J.E.T. FOX & F. KOSTALANSKA. 1989. Extrinsic and intrinsic neural control of pyloric sphincter in the dog. J. Physiol. (Lond.) 401: 17-38.
27. 27. ALLESCHER, H.D., E.E. DANIEL, J. DENT & J.E.T. FOX. 1989. Inhibitory function of VIP-PHI and galanin in canine pylorus. Am. J. Physiol. 256: G789-G797.
28. 28. VANDERWINDEN, J.-M., P. MAILLEUX, S.N. SCHIFFMANN, J.-J. VANDERHAEGHEN & M.-H. DE LAET. 1992. Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis. N. Engl. J. Med. 327: 511-515.
29. 29. TOOULI, J. & R.A. BAKER. 1991. Innervation of the sphincter of Oddi: Physiology and considerations of pharmacological intervention in biliary dyskinesia. Pharmacol. Ther. 49: 269-281.
30. 30. MELANDER, T., E. MILLBOURN & M. GOLDSTEIN. 1991. Distribution of opioidergic, sympathetic and neuropeptide Y-positive nerves in the sphincter of Oddi and biliary tree of the monkey. Macaca fascicularis. Cell Tissue Res. 266: 597-604.
31. 31. GOEHLER, L.E., C. STERNINI & N.C. BRECHA. 1988. Calcitonin gene-related peptide immunoreactivity in the biliary pathway and liver of the guinea-pig: Distribution and colocalization with substance P. Cell Tissue Res. 253: 145-150.
32. 32. KEAST, J.R., J.B. FURNESS & M. COSTA. 1985. Distribution of certain peptide containing nerve fibers and endocrine cells in the gastrointestinal mucosa in five mammalian species. J. Comp. Neurol. 236: 403-422.
33. 33. LUNDGREN, O., J. SVANVIK & L. JIVEGARD. 1989. Enteric nervous system. II. Physiology and pathophysiology of the gallbladder. Dig. Dis. Sci. 34: 284-288.
34. 34. RYAN, J.P. 1987. Motility of the gallbladder and biliary tree. In Physiology of the Gastrointestinal Tract. L.R. Johnson, Ed.:695. Raven Press. New York.
35. 35. BAUER, A.J., V.L.W. GO, T.R. KOCH & J.H. SZURSZEWSKI. 1987. Non-adrenergic, non-cholinergic (NANC) inhibitory innervation of the canine and opossum sphincter of Oddi (SO) (abstr). Gastroenterology 92: 1311A.
36. 36. DAHLSTRAND, C., A. DAHSTROM & H. AHLMAN. 1989. Adrenergic and VTP-ergic relaxatory mechanisms of the feline extrahepatic biliary tree. J. Auton. Nerv. Syst. 26: 97-106.
37. 37. SAND, J., P. ARVOLA, V. JANTTI, S. OJA, C. SINGARAM, G. BAER, P.J. PASRICHA & I. NORDBACK. 1997. The inhibitory role of nitric oxide in the control of porcine and human sphincter of Oddi activity. Gut 41: 375-380.
38. 38. ALLESCHER, H.D., S. LU, E.E. DANIEL & M. CLASSEN. 1993. Nitric oxide as putative nonadrenergic noncholinergic inhibitory transmitter in the opossum sphincter of Oddi. Can. J. Physiol. Pharmacol. 71: 525-530.
39. 39. SLIVKA, A., R. CHUTTANI, D.L. CARR-LOCKE, L. KOBZIK, D.S. BREDT, J. LOSCALZO & J.S. STAMLER. 1994. Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. J. Clin. Invest. 94: 1792-1798.
40. 40. THUNE, A., D.S. DELPRO, B. NILSSON, S. FRIMAN & J. SVANVIK. 1995. Role of nitric oxide in motility and secretion of the feline hepatobiliary tract. Scand. J. Gastroenterol. 30: 715-720.
41. 41. CULLEN, J.J., B.M. HERRMANN, R.M. THOMAS, S.Y. FANG, J.A. MURRAY, A. LEDLOW, J. CHRISTENSEN & J.L. CONKLIN. 1997. The role of antioxidant enzymes in the control of opossum sphincter of Oddi motility. Am. J. Physiol. Gastrointest. Liver Physiol. 272: G1050-G1056.
42. 42. WILEY, J.W., T.M. O'DORISIO & C. OWYANG. 1988. Vasoactive intestinal polypeptide mediates cholecystokinin-induced relaxation of the sphincter of Oddi. J. Clin. Invest. 81: 1920-1924.
43. 43. BAKER, R.A., G.T.P. SACCONE, S.J.H. BROOKES & J. TOOULI. 1993. Nitric oxide mediates nonadrenergic, noncholinergic neural relaxation in the Australian possum. Gastroenterology 105: 1746-1753.
44. 44. BAKER, R.A., T.G. WILSON, R.T.A. PADBURY, J. TOOULI & G.T.P. SACCONE. 1996. Galanin modulates sphincter of Oddi function in the Australian brush-tailed possum. Peptides 17: 933-941.
45. 45. PARODI, J.E., S.A. WYORAL, R.E. GLEASON, R. DIGEORGIO, C. STERNINI & J.M. BECKER. 1992. Immunohistochemical mapping and functional effects of galanin on the opossum sphincter of Oddi (abstr). Gastroenterology 102: A328.
46. 46. GREGERSEN, H., F.H. DALL, C.S. JORGENSEN, S.L. JENSNE & B. AHRÉN. 1992. Effects of noradrenaline and galanin on duodenal motility in the isolated perfused porcine pancreatico-duodenal block. Regul. Pept. 39: 157-167.
47. 47. CHEN, C.K., T.J. MCDONALD & E.E. DANIEL. 1994. Galanin receptor in plasma membrane of canine small intestinal circular muscle. Am. J. Physiol. 266: G113-G117.
48. 48. BOTELLA, A., M. DELVAUX, J. FIORAMONTI, J. FREXINOS & L. BUENO. 1995. Galanin contracts and relaxes guinea pig and canine intestinal smooth muscle cells through distinct receptors. Gastroenterology 108: 3-11.
49. 49. HARLING, H., T. MESSELL, S.L. JENSEN & S.S. POULSEN. 1991. Distribution and effect of galanin on gallbladder and sphincter of Oddi motility in the pig. HPB Surgery 3: 279-288.
50. 50. CULVER, P.J. & S. RATTAN. 1986. Genesis of anal canal pressures in the opossum. Am. J. Physiol. Gastrointest. Liver Physiol. 251: G765-G771.
51. 51. NURKO, S. & S. RATTAN. 1988. Role of vasoactive intestinal polypeptide in the internal anal sphincter relaxation of the opossum. J. Clin. Invest. 81: 1146-1153.
52. 52. RATTAN, S. & S. CHAKDER. 1992. Role of nitric oxide as a mediator of internal anal sphincter relaxation. Am. J. Physiol. Gastrointest. Liver Physiol. 262: G107-G112.
53. 53. CHAKDER, S. & S. RATTAN. 1996. Evidence for VTP-induced increase in NO production in myenteric neurons of opossum internal anal sphincter. Am. J. Physiol. Gastrointest. Liver Physiol. 270: G492-G497.
54. 54. LANGER, J.C. & E. BIRNBAUM. 1997. Preliminary experience with intrasphincteric botulinum toxin for persistent constipation after pull-through for Hirschsprung's disease. J. Pediatr. Surg. 32: 1059-1062.
55. 55. MARIA, G., E. CASSETTA, D. GUI, G. BRISINDA, A.R. BENTIVOGLIO & A. ALBANESE. 1998. A comparison of botulinum toxin and saline for the treatment of chronic anal fissure. N. Engl. J. Med. 338: 217-220.
56. 56. KUWAHARA, A., T. OZAKI & N. YANAIHARA. 1990. Structural requirements for galanin action in the guinea-pig ileum. Regul. Pept. 29: 23-29.
57. 57. SPEAKMAN, C.T.M., C.H.V. HOYLE, M.A. KAMM, M.M. HENRY, R.J. NICHOLLS & G. BURNSTOCK. 1993. Neuropeptides in the internal anal sphincter in neurogenic faecal incontinence. Int. J. Colorect. Dis. 8: 201-205.
58. 58. GRIDER, J.R., K.S. MURTHY, J.-G. JIN & G.M. MAKHLOUE. 1992. Stimulation of nitric oxide from muscle cells by VIP: Prejunctional enhancement of VIP release. Am. J. Physiol. Gastrointest. Liver Physiol. 262: G774-G778.
59. 59. FOX-THRELKELD, J.-A.E.T., T.J. MCDONALD, S. CIPRIS, Z. WOSKOWSKA & E.E. DANIEL. 1991. Galanin inhibition of vasoactive intestinal polypeptide release and circular muscle motility in the isolated perfused canine ileum. Gastroenterology 101: 1471-1476.
60. 60. SINGARAM, C., A. SENGUPTA, D.J. SUGARBAKER & R.K. GOYAL. 1991. Peptidergic innervation of the human esophageal smooth muscle. Gastroenterology 101: 1256-1263.
61. 61. SENGUPTA, A. & R.K. GOYAL. 1988. Localization of galanin immunoreactivity in the opossum esophagus. J. Auton. Nerv. Syst. 22: 49-56.
62. 62. KURAMOTO, H. & Y. ENDO. 1995. Galanin-immunoreactive nerve terminals innervating the striated muscle fibers of the rat esophagus. Neurosci. Lett. 188: 171-174.
63. 63. KURAMOTO, H., Y. KATO, H. SAKAMOTO & Y. ENDO. 1996. Galanin-containing nerve terminals that are involved in a dual innervation of the striated muscles of the rat esophagus. Brain Res. 734: 186-192.
64. 64. NEUHUBER, W.L., J. WÖRL, H.-R. BERTHOUD & B. CONTE. 1994. NADPH-diaphorase-positive nerve fibers associated with motor endplates in the rat esophagus: A new evidence for coinnervation of striated muscle by enteric neurons. Cell Tissue Res. 276: 23-30.
65. 65. SAND, J., H. TAINIO & I. NORDBACK. 1993. Neuropeptides in pig sphincter of Oddi, bile duct, gallbladder, and duodenum. Dig. Dis. Sci. 38: 694-700.
66. 66. SANO, J., H. TAINIO & I. NORDBACK. 1994. Peptidergic innervation of human sphincter of Oddi. Dig. Dis. Sci. 39: 293-300.
67. 67. CHRISTIANSEN, J., M. LORENTZEN & J. HOLST. 1990. Influence of peptides on anorectal function. Ann. Med. 22: 413-418.
68. 68. LARSSON, L.T., G. MALMFORS & F. SUNDLER. 1988. Neuropeptide Y, calcitonin gene-related peptide, and galanin in Hirschsprung's disease: An immunoctytochemical study. J. Pediatr. Surg. 23: 342-345.
69. 69. LYNN, R.B., S.L. SANKEY, S. CHAKDER & S. RATTAN. 1995. Colocalization of NADPH-diaphorase staining and VIP immunoreactivity in neurons in opossum internal anal sphincter. Dig. Dis. Sci. 40: 781-791.
70. 70. GUO, R., O. NADA, S. SUTTA, T. TAGUCHI & K. MASUMOTO. 1997. The distribution and co-localization of nitric oxide synthase and vasoactive intestinal polypeptide in nerves of the colons with Hirschsprung's disease. Virchows Arch. Int. J. Pathol. 430: 53-61.
71. 71. PALMER, J.M., M. SCHEMANN, K. TAMURA & J.D. WOOD. 1986. Galanin mimics slow synaptic inhibition in myenteric neurons. Eur. J. Pharmacol. 124: 379-380.
72. 72. TAMURA, K., J.M. PALMER & J.D. WOOD. 1987. Galanin suppresses nicotinic synaptic transmission in the myenteric plexus of guinea-pig small intestine. Eur. J. Pharmacol. 136: 445-446.
73. 73. FOX, J.E.T., T.J. MCDONALD, F. KOSTOLANSKA & K. TATEMOTO. 1986. Galanin: An inhibitory neural peptide of the canine small intestine. Life Sci. 39: 103-110.
74. 74. BAUER, F.E., A. ZINTEL, M.J. KENNY, D. CALDER, M.A. GHATEI & S.R. BLOOM. 1989. Inhibitory effects of galanin on postprandial gastrointestinal motility and gut hormone release in humans. Gastroenterology 97: 260-264.
75. 75. KATSOULIS, S., W.E. SCHMIDT, H. SCHWORER & W. CREUTZFELDT. 1990. Effects of galanin, its analogues and fragments on rat isolated fundus strips. Br. J. Pharmacol. 101: 297-300.
76. 76. HARLING, H. 1993. Galanin: A candidate neurotransmitter in the porcine gastrointestinal tract. Danish Med. Bull. 40:511-518.
77. 77. MAGGI, C.A., R. PATACCHINI, P. SANTICIOLI, S. GIULIANI, D. TURINI, G. BARBANTI, P. BENEFORTI, D. MISCRI & A. MELL. 1989. Human isolated small intestine: Motor responses of the longitudinal muscle to field stimulation and exogenous neuropeptides. Naunyn Schmiedeberg's Arch. Pharmacol. 339: 415-423.
78. 78. BROWN, D.R., K.R. HILDEBRAND, A.M. PARSONS & G. SOLDANI. 1990. Effects of galanin on smooth muscle and mucosa of porcine jejunum. Peptides 11: 497-500.
79. 79. HARLING, H. & A. TOTTRUP. 1991. Motility regulating effects of galanin on smooth muscle of porcine ileum. Regul. Pept. 34: 251-260.
80. 80. GRIDER, J.R. & G.M. MAKHLOUE. 1988. The modulatory action of galanin: Potentiation of VIP-induced relaxation in isolated smooth muscle cells (Abstr). Gastroenterology 94: A157.
81. 81. KUWAHARA, A., T. OZAKI & N. YANAIHARA. 1989. Galanin suppresses neurally evoked contractions of circular muscle in the guinea-pig ileum. Eur. J. Pharmacol. 164: 175-178.
82. 82. YAU, W.M., J.A. DORSETT & M.L. YOUTHER. 1986. Evidence for galanin as an inhibitory neuropeptide on myenteric cholinergic neurons in the guinea pig small intestine. Neurosci. Lett. 72: 305-308.